摘要:

Dermatoglyphic traits were studied in a sample of 834 subjects selected from a cohort of some 8,000 living Japanese men, under a long-term study of heart disease in Hawaii. All of them were born between 1900 and 1919. Among them, 100 subjects had had positive diagnosis of myocardial infarction (MI). The present study included comparisons between the MI patients and the remaining group of all digital dermal pattern types and ridge counts by digit, by hand, and by individual. The MI patients had significantly higher frequency of true whorls, double loops and less ulnar loops and tented arches. Total and absolute ridge counts were significantly higher (<0.05) in all digits in favor of the MI patients. Similar trends were observed in analyses by digit and by hand. These observations suggest an antenatal origin of certain types of coronary disease.

ISSN:0001-5652    

DOI:10.1159/000152924

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

The mean inbreeding coefficients found for Minami-cho (366 couples) and Shinsei-cho (511 couples) were 0.00307 and 0.00191, respectively. The mean inbreeding coefficient decreased and the mean marital distance increased as the year of marriage becomes more recent. The mean distances and their standard deviations between birthplaces of mates, father-offspring, mother-offspring, and sibs are 69.05 ± 229.64, 73.09 ± 246.66,49.81 ± 158.43, and 39.53 ± 159.51 km, respectively, at Minami-cho. These values are 188.45 ± 387.05, 187.79 ± 562.59, 148.26 ± 326.35, and 73.93 ± 225.92 km, respectively, at Shinsei-cho. The dimensionality of migration is closest to one di

ISSN:0001-5652    

DOI:10.1159/000152925

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

Placental alkaline phosphatase phenotypes have been determined for a large Canadian population. The ‘common’ alleles, PL1, PL2, and PL3 have frequencies similar to those of European populations. Five new phenotypes are described and the incidence of rare phenotypes is compared for several populati

ISSN:0001-5652    

DOI:10.1159/000152926

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

Genetic differentiation among the 22 Dhangar castes of Maharashtra, India, is studied using data on several polymorphic serological and biochemical loci employing Nei’s distance measures. The intercaste genetic distances and the coefficient of gene diversity among these caste groups are found to be rather small. The relationship between gene identity and geographic distance is also studied empirically from the gene frequency data. All these analyses indicate that genetic differentiation among the Dhangar castes is at its very early stage only. It is also suggested that these caste groups probably originated from a common stock and are in the process of differentiation by fission with very little intercaste migration in the recent pas

ISSN:0001-5652    

DOI:10.1159/000152927

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

In a study of Malaysians of different racial groups, 1,510 sera (908 from Malays, 371 from Chinese and 231 from Indians) were identified for their protease inhibitor (Pi) types. The gene frequencies for the alleles PiM, PiS and PiX in Malays were, respectively, 0.979, 0.015, and 0.007. In Chinese, the frequencies were 0.981, 0.019 and 0.000, and in Indians they were 0.976, 0.024, and 0.000. It is interesting that the usually rare PiX type is found in appreciable frequency in the Malays. Two different types with unusual behavior and obscure origin were also found.

ISSN:0001-5652    

DOI:10.1159/000152928

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

Frequencies of serum groups (Hp and Gc) and red cell enzyme types (PGM1, 6-PGD and ES D) were studied in 195 patients with affective disorders. The patients were classified into four groups: (1) bipolar (manic-depressive) psychosis; (2) unipolar, recurrent, depressive psychosis; (3) non-psychotic reactive depression, and (4) unclassifiable. The Hp2 gene was increased in reactive and unclassifiable patients, the PGM11 gene was increased in bipolar patients and the ES D1 gene in reactive patients. No associations were found between affective disorders and the Gc and 6-PGD systems.

ISSN:0001-5652    

DOI:10.1159/000152929

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

Frequencies of ABO, Rh, MNSs, P, Kell, Lewis and Duffy blood groups were studied in a total of 219 patients with affective disorders. The patients were classified into four groups: (1) bipolar (manic-depressive) psychosis; (2) unipolar recurrent depressive psychosis; (3) nonpsychotic ‘reactive’ depression, and (4) ‘unclassifiable’. The following statistically significant results were found: an increased frequency of the blood group factor B among psychotic (bipolar and unipolar) patients compared to non-psychotic patients, a decreased frequency of the SS phenotype in the unclassifiable group and an increased frequency of the K(+) phenotype among the nonpsychotic patients. Previous results concerning differences between bipolar and unipolar patients with respect to the A and·blood types were not confirmed in this inves

ISSN:0001-5652    

DOI:10.1159/000152930

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

Frequencies of various hemoglobinopathies were examined in a total of 1,922 individuals of Eti-Turk origin by electrophoretical techniques. Hemoglobin A2 (Hb A2) and hemoglobin F (Hb F) determinations were also performed in 651 and 1,642 cases, respectively. Mean hemoglobin S (Hb S) frequency was found to be 15.3%. Variations among the different age groups were insignificant. Hemoglobin E (Hb E) and β-thalassemia frequencies were 0.47 and 1.23%, respectively. Hemoglobin Hacettepe and hemoglobin D were found once. Red cell glucose-6-phosphate dehydrogenase (G6PD) deficiency was found in 6.5% of males

ISSN:0001-5652    

DOI:10.1159/000152931

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

812 West Malaysian Orang Asli belonging to four ethnic groups were surveyed for adenosine deaminase (ADA; EC 3.5.4.4) using starch gel electrophoresis. Only the common ADA1 and ADA2 alleles were found, with the frequencies of the latter being 0.025, 0.103, 0.115 and 0.028 in the Semai, Semelai, Temuan, and Jakun groups, respectively. A new ‘breeding genetic distance’ was applied to these gene frequencies and the Semelai and Temuan were found to be more closely related to each other, and to have considerably more evolutionary flexibility on this scale of ‘micro-evolution’ than the other two groups. The Semai and Jakun were more similar to each other on the basis of these ADA gene freq

ISSN:0001-5652    

DOI:10.1159/000152932

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

Phenotype and gene frequencies are presented for eight polymorphic systems among the Nubians of South Egypt, namely, acid phosphatase, glucose-6-phosphate dehydrogenase, adenylate kinase, 6-phosphogluconate dehydrogenase, esterase D, phosphoglucomutase I, peptidase A, and haptoglobin. Eleven systems, namely, albumin, ceruloplasmin, hemoglobin, lactate dehydrogenase, isocitrate dehydrogenase, phosphohexose isomerase, malate dehydrogenase, peptidase B and C, phosphoglucomutase II, and transferrin were found to be monomorphic. A single electrophoretic variant of phosphohexose isomerase was observed.

ISSN:0001-5652    

DOI:10.1159/000152933

出版商:S. Karger AG    

年代:1978

数据来源: Karger