摘要:

A family analysis using lod scores indicates no close linkage between MNSs and the red cell acid phosphatase.

ISSN:0001-5652    

DOI:10.1159/000152776

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

An electrophoretic survey of variant red cell enzyme phenotypes in an isolated community in Newfoundland gave gene frequencies in marked contrast to those found in the capital, St. John’s. In particular, a variant of red cell superoxide dismutase (SOD) gave a high variant frequency. Possible origins of the variant SOD allele are discusse

ISSN:0001-5652    

DOI:10.1159/000152777

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

Investigations on 70 German families with 142 children confirmed the autosomal-dominant inheritance of Gm(4). However, in our material as well as in the materials published so far, Gm(4) × Gm(–4) parental combinations show clear surplusses of Gm(4) and deficits of Gm(–4) children, which might indicate prenatal selection. The world distribution of Got4 alleles reveals a remarkable racial heterogeneity. Furthermore, marked North-South distribution gradients in Caucasoids and Mongoloids were found. The gene-tical and population genetical observations are discu

ISSN:0001-5652    

DOI:10.1159/000152778

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

Serum samples from 197 individuals belonging to the caste groups of Brahmin (37), Bania (39), Khatri (73) and Jat (48) were electrophoretically examined for the haptoglobin and transferrin systems. Intercaste variation was considered and comparisons made between these North Indian populations and those in other parts of the Indian subcontinent. A single Khatri individual was typed CB.

ISSN:0001-5652    

DOI:10.1159/000152779

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

Based on the hitherto published population data of the human red cell PGM1 and acid phosphatase polymorphisms, the geographical distributions of their gene frequencies were analyzed. As far as the acid phosphatase alleles are concerned, a marked geographical gradient was found as the Pa and Pb alleles showed significant correlations with the mean annual temperatures of the various human biotopes (Pa:r = –0.706; Pb:r = +0.812). Against that, the world distribution of the PGM1 alleles did not show a comparable correlation (PGM11:r = +0.063; PGM21:r = –0.063). The possible reasons for the distribution pattern of the acid phosphatase alleles are discus

ISSN:0001-5652    

DOI:10.1159/000152780

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

The phenotype and gene frequencies of the following polymorphisms are given for the blood samples taken from 448 adults of the South-West African Dama Negro tribe: ABO (with sub-groups), MN, Rh, K, Hp, Gc, Gm(l,2, b), lnV(l). The frequencies are discussed in comparison with other African samples and a multivariate comparison between series from south-western Africa is conducted. The Dama prove to be relatively independent.

ISSN:0001-5652    

DOI:10.1159/000152781

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

In a forensic case of disputed paternity an apparent mother/child incompatibility with respect to red cell acid phosphatase was found, the mother appearing as type A and the child as type B. Determination of electrophoretic type and of acid phosphatase activity in 8 of the family members strongly suggested the presence of a silent gene P° in 4 of the individuals. The phosphatase levels in the four heterozygotes were about half the values expected from normal values determined in 100 healthy adults representing the different phenotypes. The distribution of red cell acid phosphatase types in 3,735 unrelated Danish adults and in 1,109 mother/child pairs is reported; gene frequencies Pa = 0.369, Pb = 0.566 and Pc = 0.065. The P° gene frequency was roughly estimated as 0.001. Results are reported on the application of the red cell acid phosphatase system to 300 2-men cases of disputed paternit

ISSN:0001-5652    

DOI:10.1159/000152782

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

The authors investigate the distribution of electrophoretic patterns of pancreatic amylase in 319 Sardinians and in 476 blood donors living in Naples. The results obtained show a difference in the phenotype frequency of the Amy2 duplication variant between Sardinians (1.25%) and Neapolitans (5.25%) which is statistically significant (p < 0.01). This further confirms that Sardinians show peculiar ethnic characteristics as compared to other Caucasian groups, even to those living in the Mediterranean area.

ISSN:0001-5652    

DOI:10.1159/000152783

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

A male infant with hypertelorism, hypospadias, swallowing difficulties with tendency to regurgitation and cough, high arched palate, and a delicate voice, consistent with the G syndrome, is reported. In the family the same symptoms in addition to cleft lip and palate were known in several family members through four generations. In the females only slight manifestations of the syndrome were found, and in the males variable expression of symptoms was observed. Autosomal dominant inheritance is likely, but X-linked inheritance cannot be ruled out.

ISSN:0001-5652    

DOI:10.1159/000152784

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

α-Fetoprotein has been determined in cord blood from mono- and dizygotic twins and in a case of quadruplets. The possibility of superfetatio has been evaluated by the clinically calculated gestational ages and by the α-fetoprotein levels in cord blood, especially in a case of quadruplet

ISSN:0001-5652    

DOI:10.1159/000152785

出版商:S. Karger AG    

年代:1976

数据来源: Karger