ISSN:0250-6807    

DOI:10.1159/000176192

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

The nutritional effects of oxidized tannic acid in rats have been compared with the effects of tannic acid supplemented or not with a reductor: sodium sulfite. The results indicate that in the group which ingested oxidized tannic acid, fecal nitrogen excretion is lower than in the group which ingested tannic acid; its action on growth is mainly exerted by reduction of the retention coefficient; urinary nitrogen excretion being increased. With regard to the other groups of animals, oxidized tannic acid decreases the weight gain of the thymus and slightly increases the weight gain of the heart. Sulfite supplementation does not change the effects of tannic acid on growth; nevertheless, a higher weight gain of the kidneys is noted.

ISSN:0250-6807    

DOI:10.1159/000176193

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

The catabolic effect of bilateral lesions in the ventromedial area of the hypothalamus (VMH) was studied in nitrogen-balance experiments and compared with the effect of a sham-operation in control animals. A transitory (24 h) increase in urine nitrogen was found in the controls, while in the lesioned animals, a persistent increase was found as long as the animals were fed. Fasting (48 h) eliminated the difference in urea excretion between the groups. Food-dependent effects of the VMH lesion are suggested. The changes in body and organ composition of VMH-lesioned animals, kept for 4 months on a food intake close to normal, were studied. The massive increase of body lipids and marked decrease of body protein and water was primarily due to increased subcutaneous – and abdominal – fat, and reduced skeletal and skin protein. An almost normal composition of the liver and close to normal amounts of protein in the viscera demonstrate that at least some tissues in VMH animals are able to maintain a normal protein content. Hyperphagia as a means to counteract the increased amino acid catabolism and to sustain the lean body mass is discus

ISSN:0250-6807    

DOI:10.1159/000176194

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

The addition of 5% gum guar to a diet containing 10% casein did not change the overall N retention of young rats but induced a significant shift in the N excretion from urine to feces, resulting in a markedly decreased apparent protein digestibility. The increase in total fecal dry matter over control values accounted for only 30% of the ingested gum guar implying that 70% was absorbed, possibly after being degraded by intestinal microorganisms. The elimination of 14C activity following oral application of 14C protein indicated an accelerated turnover of amino acids during the first 3 h. After 25 h no difference between experimental and control animals was evident with respect to 14C activity remaining in the carcass. The transit time of food, as determined by neutron activation analysis of an Ytterbium marker, was somewhat decreased in the presence of gum guar.

ISSN:0250-6807    

DOI:10.1159/000176195

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

Albumin metabolism was followed in 7 patients suffering from benign gastric diseases. The study was performed using human serum albumin-125I before gastric surgery and after operation. The total albumin pool decreased after the operation by about 15%. The decrease in extravascular albumin pool was stronger (by about 19%) than the decrease in intravascular albumin pool (at about 11%). The causes of changes in albumin metabolism after surgery are discussed.

ISSN:0250-6807    

DOI:10.1159/000176196

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

Weanling rats were fed a semipurified diet based on 10% casein and 1,500 ppm potassium cyanide. The diet was supplemented with varying levels of DL-methionine and/or potassium sulfate such that all diets were iso-sulfurous except for the basal which had no additional sulfur. The animals were fed for 2 weeks after which half of the rats in all groups except the basal were used in a radioactive study. Urine was collected and analyzed for thiocyanate. Animals which received labeled methionine were more efficient in producing labeled thiocyanate than those which received labeled sodium sulfate, although the latter did contribute to the detoxification of cyanide. Increases due to additional methionine were larger for weight gain, feed consumption, and urinary and plasma thiocyanate than with supplemental sulfate.

ISSN:0250-6807    

DOI:10.1159/000176197

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

The biological value (BV) of an amino acid mixture, according to the potato-egg principle (KE), was determined in the case of oral and parenteral input with three healthy adult volunteers in a long-term complete test of metabolic balance: KE-amino acid pattern with oral input, BV = 134.4; KE-amino acid pattern with parenteral input, BV = 131.4; egg protein (reference) with oral input, BV = 100. The long-term metabolic balance experiment with human subjects under criteria of compensated nitrogen balances was used to test nitrogen substances like whole egg protein and amino acids (under parenteral and oral input); the BV of a nitrogen substance is defined as the reciprocal value of the minimum nitrogen requirements compared with the reference protein whole egg, which is set at 100. The results confirm in principle (1) the almost identical utilization and value of identical nitrogen substances (amino acids), even with different ways of input with oral and parenteral nutrition of the human being, and (2) the ability of reproduction of the BV of the optimal potato-egg protein mixture (65% potato nitrogen + 35% egg nitrogen with oral input: BV = 137.6) by means of simulation through corresponding L-amino acids, considering the modification necessary for technical as well as physiological reasons, which concern the non-essential part of the pattern.

ISSN:0250-6807    

DOI:10.1159/000176198

出版商:S. Karger AG    

年代:1978

数据来源: Karger

ISSN:0250-6807    

DOI:10.1159/000176199

出版商:S. Karger AG    

年代:1978

数据来源: Karger