ISSN:0250-6807    

DOI:10.1159/000175737

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0250-6807    

DOI:10.1159/000175738

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

Serum vitamin B12 levels were assayed in 25 healthy and 35 protein-malnourished children aged 1 -6 years. Serum proteins and haematocrit values of the children were also measured. Liver enlargement was estimated clinically. The mean serum vitamin B12 activity among protein-malnourished children was slightly higher than that for the control group. Serum vitamin B12 activity of the healthy Nigerian children was, however, high, and possible reasons for this are discussed in detail. There was some correlation between very high serum vitamin B12 levels among the protein-malnourished children and incidence of liver enlargement.

ISSN:0250-6807    

DOI:10.1159/000175683

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0250-6807    

DOI:10.1159/000175740

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

Administration of Freund’s adjuvant to cholesterol-fed rabbits inhibited the induction of atheroma in the aorta of rabbits when compared with cholesterol-fed india-ink-treated animals and cholesterol-fed saline-treated controls. Simultanously the blockade of the reticuloendothelial system by india ink caused a greater degree of atheromatous lesions in these rabbits. Smears of peripheral blood studied by light microscopy revealed the presence of circulating lipophages which were morphologically similar to the aortic foam cells isolated from the same animal. Isolation of mononuclear lipid-containing foam cells from aortic intima and the presence of a morphologically similar type of cell in circulating blood indicate that the blood might be the most likely source of intimal foam cell

ISSN:0250-6807    

DOI:10.1159/000175684

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0250-6807    

DOI:10.1159/000175741

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0250-6807    

DOI:10.1159/000175742

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0250-6807    

DOI:10.1159/000175743

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

A statistically significant inverse association was generally found between plasma total lipid, cholesterol, or phospholipid and biotin status of 300-day-old male inbred BHE (IN-BHE) rats. Plasma, liver, and carcass lipid of both sexes generally had a significant direct association with liver lactate dehydrogenase activity; an inverse association in males resulted with improved biotin status. Elevated plasma lactate indicative of anaerobic glycolysis was found. It is proposed that an increased reductive environment – a consequence of accumulated NADH – could account for enhanced triglyceride synthesis and that this effect could explain the obesity in the IN-BHE rats. After the injection of 300 µg of biotin, plasma levels of lactate and pyruvate fell in male rats, indicating a stimulatory effect of biotin upon the oxidative pathways in these ani

ISSN:0250-6807    

DOI:10.1159/000175686

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0250-6807    

DOI:10.1159/000175744

出版商:S. Karger AG    

年代:1976

数据来源: Karger