ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1983.tb00826.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1983.tb00827.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

SummaryComplete blood counts, differential white blood cell and platelet counts were performed on male and female BB Wistar diabetic rats (BBWd), their nondiabetic siblings (BBWnd) and outbred Wistar rats of the line from which the BB Wistar rats were derived. Most of the observed changes were strain‐related (those present in both BBWd and BBWnd but not in control rats) rather than diabetes‐related (those in BBWd but neither BBWnd nor control rats) and therefore probably due to the inbreeding process. The BBW strain had significantly lower numbers of white cells and platelets, as well as markedly changed differential white cell counts. Differential counts showed a pattern of lympho‐penia, neutrophilia, monocytosis and eosino‐philia. It is possible that these white blood cell changes contribute to the increased susceptibility to infection reported for the BBW strain. No significant difference in serum immunoglobulin concentrations was found in any of these three groups of rats. Therefore, hypogammaglobulinemia cannot account for the increased susceptibility to infections, but it is not possible to rule out an abnormality in the distribution of immunoglobulin fractions as an etiological

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1983.tb00828.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

SummarySerum consistuents were determined for 14 healthy pigs after the addition of hemoly‐sates containing 54, 133, 215 and 400 mg/dl of hemoglobin to serum. Of sixteen chemical procedures considered, changes (P<0.0005) in creatinine, total protein, Pi, alanine amino‐transferase (ALT), lactate dehydrogenase (LDH), Ca, K, aspartate aminotransferase (AST), total bilirubin and albumin values occurred following the addition of a hemo‐lysate containing 400 mg/dl of hemoglobin. Changes (P<0.0005) were also observed in certain serum constituents when hemoly‐sates containing 54, 133 and 215 mg/dl of hemoglobin wer

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1983.tb00829.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1983.tb00830.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1983.tb00831.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY