ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1987.tb00452.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1987.tb00453.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1987.tb00454.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

SummaryPlasma Antithrombin III (ATIII) activity was quantitated in 24 clinically normal Standardbred/Thoroughbred horses using a clotting time technique. ATIII activity ranged from 80 to 106% of the pooled reference standard plasma, with a mean of 94%. Horses presenting with impaction or spasmotic colic (n = 17) had normal plasma ATIII activity, while 15 horses presenting with acute diarrhea/colitis had significantly lower plasma ATIII activity with a mean of only 74% of the reference plasma. Seven horses presenting with liver disease had significantly higher plasma ATIII activity with a range of 127 to 177% of the pooled reference plasma.Fifty‐seven equine plasmas were retested using a rapid chromogenic substrate technique for quantitating plasma ATIII activity. A good correlation (r = +0.83) existed between clotting time and chromogenic determinations of ATIII.Pooled normal canine, human and bovine plasmas had only 65, 62 and 79%, respectively, of the ATIII activity of the equine reference plasm

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1987.tb00455.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

A fine needle aspirate was taken from an enlarged prescapular lymph node from an 8‐year‐old male Doberman Pinscher. Squash preparations were prepared for cytologic examination by air‐drying and staining with Wright's stain (Hema‐Tek Stainer:Ames Laboratories). Cytologically, the mass consisted of a population of non‐cohesive, variably sized (15 to 30 μ m) round to oval cells enmeshed in a background of eosinophilic finely fibrillar extracellular matrix material. The cells contained slightly oval to round nuclei which were occasionally eccentric in location. The chromatin was moderately hyperchromic and most nuclei contained a single prominent round nucleolus. A few cells contained multilobulated nuclei or were multinucleate. Cytoplasm was abundant, lightly to deeply basophilic and moderately granular

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1987.tb00456.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

SummaryDyserythropoiesis characterized by enhanced intramedullary destruction, pathologic sidederoblasts and siderocytes, and hemoglobin crystallization was detected in a female Cocker Spaniel presented for poor exercise tolerance. Examination of peripheral blood revealed intraerythrocytic crystals, granulation of erythrocytes, nucleated erythroid cells, reticulocytosis and marked variation in erythrocyte morphology in the absence of anemia. Bone marrow examination revealed sideroblasts, a low M:E ratio and evidence of enhanced intramedullary destruction of erythroid cells. Electron microscopy of peripheral blood and bone marrow confirmed pathologic mitochondrial iron accumulation in erythroid cells and the presence of intraerythrocytic hemoglobin crystals. A cause for the hematologic changes was not identified. After the animal became clinically normal, siderocytes disappeared from peripheral blood but intraerythrocytic crystals and reticulocytosis persisted.

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1987.tb00457.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

SummaryFree radicals are any molecules having an odd number of electrons. These molecules are highly reactive and can be generated as byproducts of normal metabolism as well as by exposure to a number of environmental factors including drugs, radiation and air pollutants. Due to the ubiquity of molecular oxygen, the oxygen metabolites superoxide anion, hydrogen peroxide, and the hydroxyl radical are frequently involved in both beneficial and detrimental free radical reactions. Intracellular enzymes and radical scavengers help to protect against tissue damage by these reactive metabolites. The extent of free radical damage to tissue depends on the nature of the radical produced and its site of generation.

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1987.tb00458.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY