ISSN:1522-0443    

出版商:OVID    

年代:2001

数据来源: OVID

摘要:

ObjectivesTo validate a concentric needle electromyography (EMG) and nerve conduction study (NCS) protocol for the preoperative analysis of brachial plexus lesionsMethods. 184 consecutive patients with traumatic brachial plexus lesions were analyzed. The results of the neurophysiological studies were compared with the final diagnoses based on the results of computed tomography-myelography and findings during the operation.ResultsThe protocol proved reliable in the analysis of these lesions in 84% of cases, limitations were that extnforaminal lesions may mask root avulsion or central lesions; paraspinal sampling is of limited value in multiple root lesions because of the overlap in innervation; and sometimes normal sensory nerve action potentials (SNAPs) could occur in an extra foraminal lesion. Lesions outside the plexus were found in 21% of the patients, most of which would not have been expected on clinical grounds.ConclusionWith this protocol, a reliable analysis of traumatic brachial plexus lesions can be made in 84% of the patients, even finding lesions outside the brachial plexus not expected on clinical grounds in 2l° of the patients.

ISSN:1522-0443    

出版商:OVID    

年代:2001

数据来源: OVID

摘要:

ObjectivesTo define the clinical, electrophysiological, and pathologic features of the myopathy associated with the use of HMG CoA reductase inhibitorsMethods.: Five patients with myopathy associated with HMG CoA reductase inhibitors were evaluated. Complete histories, physical examinations, manual muscle testing, serum creatine kinase, urine myoglobin measurements, electrodiagnoscic studies, and muscle biopsy were performed.ResultsConsistent features in our patients included a subacute onset of myalgias and weakness, electromyography demonstrating electrical myotonia, elevated creatine kinase levels, and in some patients myoglobinuria despite a relative lack of muscle necrosis on muscle biopsy and preserved myofibrillatory architecture by electron microscopy. All patients experienced resolution of symptoms within 3 weeks of drug discontinuation.ConclusionsWe postulate that the constellation of clinical, electrophysiological, and pathologic findings among our patients with HMG CoA reductase inhibitor myopathy may be explained by the early toxic effects of HMG CoA reductase inhibitors on muscle membrane organelles and sarcolemmal function. Patients on concurrent therapy with cyclosporine, gemfibrozil, and antifungal agents of the azole groups are at an increased risk of developing this toxic myopathy.

ISSN:1522-0443    

出版商:OVID    

年代:2001

数据来源: OVID

摘要:

A 62-vear-old man presented with an acute onset of symmetric upper and lower extremity paresthesias. Neurological examination showed normal motor strength throughout with areflexia and reduced vibratory and proprioceptive sense in all four extremities. A lumbar puncture performed 6 weeks after onset demonstrated elevated cerebrospinal fluid protein with no cells. Electrodiagnostic testing 7 weeks after onset revealed a primarily sensory neuropathy with normal motor conduction and needle electromyographic studies Symptoms stabilized within 3 weeks of onset and improvement began within 2 months. Except for the absence of motor disturbance, this case appears to resemble Guillain-Barré syndrome.

ISSN:1522-0443    

出版商:OVID    

年代:2001

数据来源: OVID

摘要:

We describe a patient with acquired thrombin inhibitor who developed tibial and peroneal neuropathies followed by lumbar plexopathy as a result of large calf and psoas muscle hematomas. Thrombin time, Prothombin time, and partial thromboplastin time were prolonged after repeated exposures to topical bovine thrombin in two orthopedic procedures Specific coagulation tests revealed that the coagulopathy was the result of an inhibitor to bovine thrombin that cross-reacted with human thrombin. We emphasize the risk of spontaneous hematomas that can compromise peripheral nerves as a result of an acquired coagulopathy following bovine thrombin exposure.

ISSN:1522-0443    

出版商:OVID    

年代:2001

数据来源: OVID

ISSN:1522-0443    

出版商:OVID    

年代:2001

数据来源: OVID

摘要:

This brief review was written with the intention of familiarizing the reader with autonomic peripheral neuropathies. We have discussed what we think are the main presenting symptoms of these conditions, briefly outlining some specific autonomic neuropathies. We then provide a general guideline to evaluation and diagnosis by using both widely available, as well as more sophisticated, techniques. Finally, we have addressed management. Whenever possible, specific treatment of underlying disorders leads to the best outcome However, for many autonomic neuropathies, no cure is available, although symptomatic management can effectively improve patients“ quality of life.

ISSN:1522-0443    

出版商:OVID    

年代:2001

数据来源: OVID

摘要:

Creatine kinase (CK) is the single most important biochemical test in the evaluation of patients with myopathies. In health, serum CK concentration is higher in men, blacks, muscular individuals, and athletes. Idiopathic hyperCKemia is an entity restricted to asymptomatic patients with a negative family history for a neuromuscular disease acid normal neurological, electrodtagnostic. and histologic examinations. Serum CK concentration in myopathy correlates with seventy of illness, course of disease, available muscle mass, and myofiber necrosis. CK may be elevated in neurogenic disorders, particularly in Kennedy's disease and type III spinal muscular atrophy.

ISSN:1522-0443    

出版商:OVID    

年代:2001

数据来源: OVID

ISSN:1522-0443    

出版商:OVID    

年代:2001

数据来源: OVID

ISSN:1522-0443    

出版商:OVID    

年代:2001

数据来源: OVID