ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1974.tb01357.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

SummaryA comparison was made between the effects of prior inhalation of sodium cromogly‐cate or beclomethasone dipropionate on immediate, late and dual asthmatic reactions to provocation challenge tests with a range of allergens. Whereas sodium cromoglycate inhibited immediate and dual asthmatic reactions, beclomethasone dipropionate had no effect on immediate asthmatic reactions, but consistently inhibited late asthmatic reaction

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1974.tb01358.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

SummaryTheDermatophagoidesmites are well recognized as allergens in bronchial asthma. A survey of mattress dust in Birmingham showed large numbers ofEuroglyphus mayneito be present in addition. A variation was found in mite populations in dust collected by vacuum cleaner when compared to brushed samples, which may explain previous findings of only small numbers ofE. maynei. A mean density of 296 pyroglyphid mites; 100 μg dust was found in mattress dust.Glycyphagusspecies formed only 1%, of all mites seen

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1974.tb01359.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

SummaryA double blind controlled trial of a house mile fortified house dust vaccine was carried out in forty‐two asthmatic patients between the ages of 6 and 15 years. Improvement in height and weight was shown in eight of twenty‐one children receiving the active therapy compared with one of twenty‐one children receiving placebo injections. No difference between the two groups was shown by respiratory function testing or chest examin

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1974.tb01360.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

SummaryA patient is described who developed a pulmonary hypersensiiivity reaction to sulphasalatzine used in the treatment of his ulcerative colitis. Challenge testing demonstrated that the patient was sensitive to the sulphapyridine component of the drug. The pulmonary response consisted of an immediate bronchial obstructive reaction and a late parenchymal reaction with fall in gas transfer factor. Detailed immunological testing failed to define the mechanisms of drug toxicity.

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1974.tb01361.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

SummaryGrass pollen extract adsorbed on to a suspension of L‐tyrosine has been tested over 2 years as a treatment for hay fever. Eight‐ or nine‐dose courses terminating at doses of between 1000 and 10,000 Noon units were equally effective when compared either with a placebo or with a pyridine‐extracted alum prec

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1974.tb01362.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

SummaryAtopic subjects treated with pollen‐tyrosine showed increased IgG and IgE antibody levels; in the second year of treatment the IgE response was suppresse

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1974.tb01363.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

SummaryA typical case of pulmonary eosinophilic granuloma, ascertained by lung biopsy, is reported. Immunological studies showed multiple hypersensitivity against wood dust extracts, horse serum, horse hair and danders proteins. Inhalation of these two groups of substances reproduced most of the acute symptoms of the disease. Therefore, a causal relationship seemed highly probable.To our knowledge, this is the first case of pulmonary eosinophilic granuloma in which an allergic origin could be substantiated.

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1974.tb01364.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

SummaryAfter a latent period of 3 weeks following an intense inhalational exposure to mouldy corn, a farmer developed pneumonilis apparently of a hypersensilivity pneumonitis type. This illness was associated with serum precipitating antibodies against antigens in the mouldy corn and against antigens ofAspergillus flavusandfumigatus. The former organism was cultured from the mouldy corn and precipilin bands of identity between an extract of mouldy corn and aspergitlus antigen were demonstrated using the patient's serum. Organizing bronchiolilis oblilerans was found in pulmonary tissue after death occurred, the latter presumably due to pulmonary embolism. This case is believed to represent the occurrence of hypersensitivity pneumonitis following massive inhalation of the spores of the genusA. flavuspossibly with transient respiratory infection with these organisms but without systemic invasion of the host.

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1974.tb01365.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

SummaryStreptomyces olivaceuswas isolated from the roof‐thatch of New Guinea huts, and a soluble extract was prepared from it. Using sera from New Guinea natives as a source of precipitating antibody, theS. olivaceusantigen showed a reaction of partial identity with antigens in crude roof‐thatch extracts.The inhalation of aerosols ofS. olivaceusantigen by guinea‐pigs, previously given parenteral doses of the same antigenic solution, induced extrinsic allergic alveo

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1974.tb01366.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY