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1. |
Ocular Symptomatology in Familial Hypomelanosis Ito |
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Ophthalmologica,
Volume 200,
Issue 1,
1990,
Page 1-6
M. Amon,
R. Menapace,
R. Kirnbauer,
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摘要:
Hypomelanosis Ito (HI) is a very rare neurocutaneous syndrome which is often associated with cutaneous, cerebral, musculoskeletal and ocular abnormalities. The paper deals with changes in familial HI (mother and daughter) with special consideration of ocular symptomatology; it also presents a review about the relevant literature published to date – not documented with photographs with one exception. The argument is raised whether all ocular changes described in HI actually belong to the syndrome or are partly a mere coincidence. There is also a description of a cataract which has never been observed in cases of HI. Electrophysiological tests (electroretinography, electrooculography, visual-evoked potential) which to date have not been carried out for HI, are presented and their results reported. Mention is also made of the hereditary factor which has so far been questioned; it is assumed that it is autosomal dominant in character. In this context, the results of a chromosome analysis in both mother and daughter are presented.
ISSN:0030-3755
DOI:10.1159/000310069
出版商:S. Karger AG
年代:1990
数据来源: Karger
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2. |
One-Piece Contact Lens for Laser Iridotomy at Iris Base by Argon and Nd:YAG Laser |
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Ophthalmologica,
Volume 200,
Issue 1,
1990,
Page 7-9
K.E. Schirmer,
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摘要:
Laser iridotomies at the base of the iris provide a free shunt between the anterior and the posterior chamber remote from the capsule of the lens. Injury to the lens capsule by the Nd:YAG laser is avoided as the iris is not in close apposition. The heterocentric applanatic lens guides the laser beam under the limbal shelf toward the root of the iris. The combined use of a thermal and an ionizing laser is preferred.
ISSN:0030-3755
DOI:10.1159/000310070
出版商:S. Karger AG
年代:1990
数据来源: Karger
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3. |
Schieloperationen bei endokrin bedingten Motilitätsstörungen |
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Ophthalmologica,
Volume 200,
Issue 1,
1990,
Page 10-15
W. Aust,
F. Schönherr,
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摘要:
In every case of an uncertain vertical diplopia one should think of an endocrine ophthalmopathy. A squint operation done in time will improve the motility of the eye. 8 of our 9 patients had no longer a diplopia after surgery and got binocular vision. 6 months after stabilization of the endocrine situation we resected and recessed the rectus muscles, especially the vertical rectus muscles, in 1 case we advanced the inferior oblique muscle. The amount of the surgical correction depended on the motility disturbance and the angle of squint which we compensated a few days before the operation by means of prisms. Postoperatively the patients got steroids parenterally.
ISSN:0030-3755
DOI:10.1159/000310071
出版商:S. Karger AG
年代:1990
数据来源: Karger
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4. |
The Relationship of Mean Defect to Corrected Loss Variance in Glaucoma and Ocular Hypertension |
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Ophthalmologica,
Volume 200,
Issue 1,
1990,
Page 16-21
Andrew Pearson,
Larry B. Baldwin,
Thomas J. Smith,
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摘要:
Statistical analysis of visual-field data is permitted by the quantitative techniques used in automated perimetry. The visual-field indices mean defect (MD) and corrected loss variance (CLV) provide an opportunity to analyze and follow visual fields mathematically. We investigated the relationship of MD to CLV in 32 glaucoma suspects and 17 patients with visual-field defects due to chronic open-angle glaucoma. In glaucoma patients with early and moderate disease (up to a MD of 18 dB), the CLV statistically covaried with the MD (R2 = 0.85). Beyond an MD of 18 dB, increases in the MD seemed to cause a decline in the CLV. These results differ from prior reports on the relationship of MD and CLV. Reasons for this and implications for the use of these statistics in the clinical management of the glaucoma patient are discussed. These results may be helpful in the understanding of the pathophysiologic basis of damage in glaucoma.
ISSN:0030-3755
DOI:10.1159/000310072
出版商:S. Karger AG
年代:1990
数据来源: Karger
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5. |
C Wave Study in Optic Neuritis due to Demyelinating Disease |
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Ophthalmologica,
Volume 200,
Issue 1,
1990,
Page 22-27
M. Moschos,
D. Brouzas,
E. Panagakis,
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摘要:
The C wave was recorded from 20 eyes suffering from neuritis due to demyelinating disease and in 5 eyes showing optic atrophy due to trauma or to increased intracranial pressure. Our results show that in cases with optic neuritis the C wave amplitude was clearly lower than normal. It is interesting that in the other ‘healthy’, at least clinically, eye the C wave was subnormal too. On the contrary, in the eyes with optic atrophy the C wave was normal. These findings are against the possibility of an efferent neuronal pathway involvement, which influences the level of the retinal pigment epithelium, and support the view of its involvement during the course of the demyelinating disease that causes the optic neuritis.
ISSN:0030-3755
DOI:10.1159/000310073
出版商:S. Karger AG
年代:1990
数据来源: Karger
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6. |
Effects of Sodium Iodate on Experimental Subretinal Neovascularization in the Primate |
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Ophthalmologica,
Volume 200,
Issue 1,
1990,
Page 28-38
Tetsuya Nishimura,
Zhi-Ren Zhu,
Stephen J. Ryan,
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摘要:
We investigated the role of the retinal pigment epithelium (RPE) in the development of subretinal neovascularization (SRN) induced by bilateral laser photocoagulation of the retinas in monkeys. RPE function was affected by a unilateral carotid injection of sodium iodate, a selective RPE toxin, before laser photocoagulation. This caused severe RPE damage in the ipsilateral eye, but did not affect the contralateral eye. After laser photocoagulation no SRN was demonstrable clinically or histopathologically in the ipsilateral eye; in contrast, active SRN showing extensive fluorescein leakage was found in the contralateral eye. These results suggest that RPE may play a role in the development of laser-induced SRN.
ISSN:0030-3755
DOI:10.1159/000310074
出版商:S. Karger AG
年代:1990
数据来源: Karger
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7. |
Activated Macrophages in Experimental Subretinal Neovascularization (With 1 color plate) |
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Ophthalmologica,
Volume 200,
Issue 1,
1990,
Page 39-44
Tetsuya Nishimura,
Randi Goodnight,
Robert A. Prendergast,
Stephen J. Ryan,
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摘要:
Laser-induced subretinal neovascularization (SRN) in monkey retinas was investigated by immunohistochemical techniques to identify the presence and location of activated macrophages. Retinal lesions were examined 3, 8 and 14 days after intensive argon laser treatment, and the distribution of interleukin-1 (IL-1)-containing cells in the lesions was determined by the orthogonal reconstruction of serial sections. Macrophages were present in the subretinal space of day 3 and day 8 lesions. These IL-1-containing cells were distributed about the area of rupture of Bruch’s membrane and were quite common in lesions taken 3 days following laser treatment. While still apparent, the number was decreased at 8 days, and none were found 14 days after laser treatment. The temporal and spatial distribution of IL-1-staining macrophages paralleled the development of SRN, suggesting a relationship between the presence of activated macrophages and the initiation of neovascularization in this model.
ISSN:0030-3755
DOI:10.1159/000310075
出版商:S. Karger AG
年代:1990
数据来源: Karger
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8. |
Retinal Pigment Epithelial Tear in Reactive Lymphoid Hyperplasia of Uvea (With 1 color plate) |
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Ophthalmologica,
Volume 200,
Issue 1,
1990,
Page 46-54
Toshihiko Matsuo,
Nobuhiko Matsuo,
Fumio Shiraga,
Kyoko Takeuchi,
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摘要:
A 76-year-old patient developed cystic exudative retinal detachment with many yellowish subretinal precipitates and a large retinal pigment epithelial (RPE) tear in midperiphery of the right eye in the course of polyclonal hypergammaglobulinemia. The left eye showed localized RPE detachment in the posterior pole which gradually extended. Systemic steroid administration reduced the subretinal precipitates to some extent, but suspicion of malignancy led to enucleation of the right eye after unsuccessful diagnostic vitrectomy. A histopathological study revealed massive infiltration of the uvea with plasma cells and small lymphocytes but no abnormal cells. This is the first report to show the association of an RPE tear with reactive lymphoid hyperplasia of the uvea.
ISSN:0030-3755
DOI:10.1159/000310076
出版商:S. Karger AG
年代:1990
数据来源: Karger
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9. |
Book Reviews |
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Ophthalmologica,
Volume 200,
Issue 1,
1990,
Page 55-56
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PDF (567KB)
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ISSN:0030-3755
DOI:10.1159/000310077
出版商:S. Karger AG
年代:1990
数据来源: Karger
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