摘要:

Two cases with a history of recurrent subretinal hemorrhaging are reported. Multinucleated giant cells of macrophage origin were demonstrated on Bruch’s membrane in a few stages of their functions of phagocytosis of old blood and storage of blood remnants. Their classification as foreign-body giant cells fails to recognize the important purification, disposal and storage functions of these cells in situations with extensive intraocular hemorrhage, exudation or necrosi

ISSN:0030-3755    

DOI:10.1159/000310017

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

An investigation was carried out into the prognostic value of standard flash electroretinography (ERG) and visual-evoked cortical potentials (VECP) recorded for 87 diabetic eyes prior to vitrectomy. 95% of the eyes with a recordable ERG b-wave achieved a post-operative visual acuity (VA) of 0.05 or better (positive predictive value), but only 35% of the eyes with a good post-operative VA had a recordable b-wave (sensitivity). The corresponding values for the ERG a-wave were 67 and 72% and for the VECP 77 and 69% respectively. A non-recordable b-wave in the ERG was associated with a poor visual outcome (VA < 0.05) in 45% of cases (negative predictive value), and 97% of the eyes with a poor visual outcome had a non-recordable b-wave (specificity). The corresponding values for the ERG a-wave were 42 and 37% and for the VECP 53 and 63% respectively. Consequently, the odds ratio for an unfavourable visual outcome (VA < 0.05) was greater for a non-recordable b-wave (15.7) than for a non-recordable VECP (3.8) or a non-recordable a-wave (1.5). Recordability of the b-wave gave the best prediction for attached macula. Extensive photocoagulation diminished all ERG and VECP amplitudes. Vitreous opacities had no significant effect on the ERG or VECP.

ISSN:0030-3755    

DOI:10.1159/000310018

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

Diabetic macular edema is shown to be treated successfully by central focal argon laser coagulation in most cases. Since February 1986, diabetic patients with macular edema were evaluated prospectively and treated by focal argon laser coagulation and/or grid pattern. A second group of diabetic patients with comparable macular edema and similar retinal changes was explored retrospectively. Visual acuity after treatment in relation to preoperative visual acuity was measured and statistically compared with visual acuity of the second group without laser treatment. The results show that laser treatment is important for stabilization of visual acuity but does not increase visual acuity beneath 0.2. Indications for treatment are discussed.

ISSN:0030-3755    

DOI:10.1159/000310019

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

Thirty-three eyes (i.e. 33 patients) with active toxoplasmic retinochoroiditis were treated and followed up for a 2 to 9 year period. The patients were divided into two groups. The first was treated with laser, while the second received medication. The division into two groups was made in order to discover possible differences between the two groups concerning success rate, time of regression of the lesion recurrences and complications. The study showed the following results: there was no difference as to the rate of overall success between the two groups. The laser produced no result in the cases where the active retinochoroidal lesion was larger than 2 disc diameters. The regression of the active lesion in the laser group was accomplished in 25–50 days, while in the medication group took 50–150 days. Recurrences after treatment were found in both groups. However, the starting point of recurrences differed in each group.

ISSN:0030-3755    

DOI:10.1159/000310020

出版商:S. Karger AG    

年代:1989

数据来源: Karger

ISSN:0030-3755    

DOI:10.1159/000310021

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

Because of some authors presumptions that acute retinal pigment epitheliitis is not a distinct clinical entity but the early stage of other fundus diseases, the results of long-term observations of 5 patients with this disease are reported. The results of 6- to 7-year observations of these patients have shown that in none of them the fundus lesions developed into other retinal diseases. This indicates that acute retinal pigment epitheliitis is a distinct clinical entity.

ISSN:0030-3755    

DOI:10.1159/000310022

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

In a prospective study, 48 eyes with non-ischaemic and 35 with ischaemic central retinal vein occlusion (CRVO) were treated by isovolaemic haemodilution (IHD). Two or more cardiovascular risk factors were present in 42% of patients with non-ischaemic and in 69% of patients with ischaemic CRVO (p < 0.025). Nevertheless, IHD in no case caused serious cardiovascular complications. Minor problems were short fainting spells in 5% and a general weakness in 16% of the haemodiluted patients. The effect of IHD was measured by determining the time of maximal venous filling (tmvf) in fluorescein angiographies. Lowering the packed cell volume to 32–35% accelerated the tmvf from 18.4+1.61 to 13.1 ± 1.0 s (p < 0.001) in eyes with non-ischaemic CRVO and from 24.5 ± 1.2 to 14.8 ± 1.3 s (p < 0.001) in eyes with ischaemic CRVO. After 3 months, an increase in visual acuity had occurred in 27% of eyes with non-ischaemic CRVO and in 48.5% with ischaemic CRVO. These improvement rates could nearly be maintained after 1 year. 59% of eyes with non-ischaemic and 25% with ischaemic CRVO were able to read (visual acuity ≥6/15) after 1 year.

ISSN:0030-3755    

DOI:10.1159/000310023

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

A comparative study of Solcoseryl® eye drops versus Vitasic® eye drops has been carried out under controlled conditions (randomized and double-blind) on a total of 94 patients. 52 had corneal erosion, 30 had dry eye syndrome, 8 cases could not be evaluated. In addition, 2 eyes with photophthalmia were treated with Vitasic and 2 showing keratitis with Solcoseryl. There were no adverse reactions other than 2 instances of stinging with Solcoseryl and 1 case of severe irritation after Vitasic. The patients were examined on days 0,1, 3 and 7. Results showed a consistent superiority of Solcoseryl eye drops in respect to speed of healing of corneal erosions and moistening of the cornea in the ‘dry eye’ syndrome which reached statistical significance in some param

ISSN:0030-3755    

DOI:10.1159/000310024

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

Funduscopic and retinal light- and electron-microscopic findings are described in an infant with progressive neurologic deterioration leading to death. Brain autopsy findings were consistent with Leigh’s disease. The retinal mitochondria showed marked degenerative changes, the cristae were almost completely destroyed and electron-dense material filled a major part of the cavity. These changes are typically described in the late stages of mitochondrial diseases but have not been described before in retinal mitochondria in a patient with Leigh’s disease.

ISSN:0030-3755    

DOI:10.1159/000310025

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

We report a case of reticulum cell sarcoma with involvement both in the brain and the eyes. The patient was a 49-year-old man. In 1985, he suffered steroid-resistant uveitis of unknown etiology in his right eye. After that, in 1986, he was aware of a weakness in the right arm and leg and of right sensory disturbances. Histopathological study of a biopsy specimen revealed a malignant lymphoma in the left thalamus, and the lesion was effectively treated by radiation to the brain. In 1987, he complained of visual disturbances in the left eye. According to the history and ocular manifestation, the disease was diagnosed as ocular reticulum cell sarcoma. Radiation therpay to his left orbital cavity was effective and inflammatory signs in the left eye subsided.

ISSN:0030-3755    

DOI:10.1159/000310026

出版商:S. Karger AG    

年代:1989

数据来源: Karger