摘要:

A series of 38 children with ocular herpes simplex infection is reported. The follow-up periods ranged between 1 and 10 years after the first ocular herpetic involvement. The primary ocular infection occurred in most cases between 2 and 6 years of age, with a similar rate in males and females. The number of recurrences increased with the duration of the follow-up period: during the first 2 years, recurrences developed in 50% of cases and after 2 years, all the children had new herpetic ocular attacks. Idoxuridine treatment failures were found in 11 cases of herpetic superficial keratitis. Ocular herpes simplex in children is a major cause of visual loss and disability. After a follow-up period of 5 years, 75% of patients with herpetic keratitis had a visual acuity of 5/10 or less.

ISSN:0030-3755    

DOI:10.1159/000309177

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

The authors have followed the evolution of disseminated choroidal tuberculosis during a period of 16 months. At the beginning of the disease, fluorescein angiography showed an early ‘screen effect’ and later a ‘focus effect’. During the later stage of the disease, the pigmented epithelium was seen to be involved as well, as demonstrated by (1) the presence of advanced pigmented chorioretinitis at the sites where the tubercles were observed at the beginning of the disease and (2) the presence of fluorescent areas early during fluorescein angiography.

ISSN:0030-3755    

DOI:10.1159/000309178

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

This paper describes a family, the propositus of which suffers from dystrophia retinae pigmentosa combined with fundus flavimaculatus and Stargardt’s disease. The patient’s mother and a maternal uncle suffer from a dystrophia retinae pigmentosa, whereas a sister shows peripheral degenerations. A further sister has a scotopic b wave of the ERG of low amplitude.

ISSN:0030-3755    

DOI:10.1159/000309179

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

A total of 56 eyes with Irvine-Gass syndrome, treated by vitrectomy, vitrectomy plus photocoagulation, or photocoagulation alone, were studied. Three possible etiologic mechanisms for the syndrome are considered. The results obtained show that there is a direct relationship between the duration of the disease and the postsurgical visual acuity.

ISSN:0030-3755    

DOI:10.1159/000309180

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

2 cases of optic disc pits complicated by macular edema are reported. In both cases, fluorescein angiography showed dye leakage from the disc into the edematous retina and was helpful in planning treatment. Laser coagulation limited to the leaking area led to prompt resorption of the subretinal fluid and to substantial improvement of vision.

ISSN:0030-3755    

DOI:10.1159/000309181

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

8 cases of tilted disc syndrome are reported; functional disturbances are analysed as well as associated malformations. The clinical importance of the syndrome is emphasised with regard to the differential diagnosis of chiasmatic disorders. Pathogenic hypotheses are discussed as well as the investigative approach indicated in these cases.

ISSN:0030-3755    

DOI:10.1159/000309182

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

A 20-year-old man with the characteristic findings of infantile onset Kearns syndrome is described. Morphological and biochemical investigations proved a mitochondrial disease which we believe to be the cause of the symptoms in various organs. We assume an autosomal-dominant inheritance, the marker sign of which is blepharoptosis in several family members. Characteristic clinical, morphological and biochemical findings, combined with an autosomal-dominant inheritance with very variable expression, mark the Kearns syndrome as an individual disease, not as a symptom complex (syndrome). Kearns disease can be divided into three forms – an infantile form (‘Kearns-Sayre syndrome’) with early onset, rapid progression, multisystemic involvement and a severe course; and a juvenile and an adult form with onset in the second, respectively third (or later) decades with a generally slower and more benign course and less widespread expression in various organ systems. Furthermore, the occurrence of a curious orthoptic abnormality is described, indicating one of the possible ways to avoid diplopia in chronic progressive external ophthalmoplegia: the coexistence of normal and gliding abnormal retinal correspondence.

ISSN:0030-3755    

DOI:10.1159/000309183

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

The classification of neutral grays is helpful for the differential diagnosis of color vision defects, especially when anomaloscopic examination is not possible. In congenital color vision defects the PR, RP region of the spectrum appears ‘dark’ to protan-defective subjects and ‘light’ to deutan-defective subjects. Acquired color vision defects have a common base type, the type III blue-yellow defect. The defect develops depending on the site of the primary lesion and also on the fixation mode. Classification of neutral grays may help in differentiating optic nerve diseases from retinal diseases; when visual functions become mediated by rods, sensitivity shifts and the BV, B region of the spectrum will appear relatively ‘light’ to the patient.

ISSN:0030-3755    

DOI:10.1159/000309184

出版商:S. Karger AG    

年代:1982

数据来源: Karger

ISSN:0030-3755    

DOI:10.1159/000309185

出版商:S. Karger AG    

年代:1982

数据来源: Karger