ISSN:0263-6484    

DOI:10.1002/cbf.290020102

出版商:John Wiley&Sons, Ltd.    

年代:1984

数据来源: WILEY

ISSN:0263-6484    

DOI:10.1002/cbf.290020103

出版商:John Wiley&Sons, Ltd.    

年代:1984

数据来源: WILEY

ISSN:0263-6484    

DOI:10.1002/cbf.290020104

出版商:John Wiley&Sons, Ltd.    

年代:1984

数据来源: WILEY

ISSN:0263-6484    

DOI:10.1002/cbf.290020105

出版商:John Wiley&Sons, Ltd.    

年代:1984

数据来源: WILEY

ISSN:0263-6484    

DOI:10.1002/cbf.290020106

出版商:John Wiley&Sons, Ltd.    

年代:1984

数据来源: WILEY

摘要:

AbstractMolybdenum in the form of its pentavalent complex binds primarily to spectrin when incubated with erythrocytes. Only the band 1 subunit is involved in this interaction thus indicating some structural differences between spectrin subunits.

ISSN:0263-6484    

DOI:10.1002/cbf.290020107

出版商:John Wiley&Sons, Ltd.    

年代:1984

数据来源: WILEY

摘要:

AbstractThe fatty acid composition of platelet membranes has been analysed in patients with thrombocytosis due to myeloproliferative disorders, who had not taken any drugs. A significant increase in palmitic and oleic acid, together with a decrease in stearic, linoleic and arachidonic acids was observed. The fatty acid pattern of platelet membranes was also analysed in patients during treatment with ASA (acetylsalicylic acid). ASA ingestion completely normalizes the platelet content of palmitic acid and partially that of stearic and arachidonic acid, whereas it has no effect on the level of linoleic acid and raises that of oleic acid. The altered pattern of fatty acids observed in patients may interfere with platelet function by decreasing membrane fluidity. Treatment of patients with ASA seems to act on platelet membranes by partially normalizing the fatty acid composition.

ISSN:0263-6484    

DOI:10.1002/cbf.290020108

出版商:John Wiley&Sons, Ltd.    

年代:1984

数据来源: WILEY

摘要:

AbstractProduction of testosterone by highly purified Leydig cells prepared from rat and mouse testes is compared. Testosterone formation is improved to a higher degree in rat (2.7‐fold) than in mouse (1.7‐fold) cells by callagenase treatment of the testis compared with mechanical isolation. Mouse Leydig cells respond to exogenous stimuli (chorigonadotropin, dibutyryl cyclic AMP) with 2.4‐fold higher testosterone secretion than rat cells. A 1.7‐fold increased conversion of androgen precursors to testosterone by mouse compared with rat Leydig cells is demonstrated in static incubations as well as in steady‐state superfusion experiments and can be derived from enhanced androstenedione reduction and a less inhibitory effect of progesterone on this process is mouse Ley

ISSN:0263-6484    

DOI:10.1002/cbf.290020109

出版商:John Wiley&Sons, Ltd.    

年代:1984

数据来源: WILEY

摘要:

AbstractNude mice were injected with DNA purified from the nucleoprotein complex released by T lymphocytes previously exposed in vitro to inactivated herpes or poliovirus. After five days the serum of these mice was tested for its virus neutralizing activity. Results show that injected nude mice synthesize antiherpetic or antipolio antibodies depending on the antigen used to sensitize the T lymphocytesin vitro. These antibodies were not found in the serum of uninjected control mice or mice injected with inactivated herpes or polio viruses. Mice injected with DNA release by human T cells produced antibodies carrying human allotypes since they could be neutralized by anti‐allotype sera. Moreover their antiviral activity was inhibited by anti‐human IgM or IgG. However, the mice which were injected with DNA released by antigen stimulated murine T lymphocytes produced antiviral antibodies which were not neutralized by anti‐human allotype

ISSN:0263-6484    

DOI:10.1002/cbf.290020110

出版商:John Wiley&Sons, Ltd.    

年代:1984

数据来源: WILEY

摘要:

AbstractInformation on the interaction between endoplasmic reticulum (ER) membranes and components of the skeletal network of the cell was gained by treating cells with the antimicrofilament agent cytochalasin B prior to cell disruption by nitrogen cavitation. Treatment of Krebs II ascites cells with cytochalasin B (5–10 μg ml−1) resulted in an increased yield of three ER membrane subfractions — heavy rough (HR), light rough (LR) and smooth (S) membranes, as judged by3H‐choline incorporation in gradient fractions following discontinuous sucrose gradient centrifugation. The major increase was observed in the HR fraction. These results indicate that the actual yield of the respective ER membrane subfractions after cell disruption is dependent on the degree of direct and/or indirect interaction between individual ER membranes and actin containing filaments of the cytoskeleton in the int

ISSN:0263-6484    

DOI:10.1002/cbf.290020111

出版商:John Wiley&Sons, Ltd.    

年代:1984

数据来源: WILEY