摘要:

The arteriole-glomerular units in different zones of the human kidney have been studied by combined stereomicro-angiographic and histologic techniques. In the cortical zone the afferent and efferent artérioles of a unit communicate solely by way of the glomerular capillaries. In the juxtamedullary zone the afferent and efferent artérioles of most of the units form continuous medullary vessels, of which the glomerular capillaries are side branches. In the fetal and neonatal kidney such continuous artérioles were found only in the pelvic area. The findings indicate the existence of an extraglomerular shunt of varying capacity for the medullary blood fl

ISSN:1660-8151    

DOI:10.1159/000179347

出版商:S. Karger AG    

年代:1964

数据来源: Karger

摘要:

The effect of angiotensin on renal transport of sodium was studied in 18 anesthetized dogs. The substance was administered into the left renal artery every 5 min during a 25-minute period. The right kidney was used as control. At 5 min, the angiotensin produced a decrease in glomerular filtration rate, renal plasma flow, and sodium and water excretion. At 25 min, glomerular filtration rate and renal plasma flow reached control values and sodium and water excretion rose above them. Sodium and water excretion fractions also increased significantly beyond control values. Afferent arteriolar resistance increased 5 min after administration of angiotensin and returned to control values at 25 min. Comparison of free water excretion and free water reabsorption in the two kidneys showed values close to zero in the right kidney and progressive increase in free water excretion in the left kidney. This seems to indicate that angiotensin acts at the proximal tubule.

ISSN:1660-8151    

DOI:10.1159/000179348

出版商:S. Karger AG    

年代:1964

数据来源: Karger

摘要:

Fifty cases of SLE have been collected over a ten year period and the incidence and clinical picture of LN reviewed in the light of other published data. Lupus nephritis, like SLE, has a variable pattern of its own with a wide spectrum of renal involvement–evaluation of therapy and prognosis will have to be conducted against this background. Lupus nephritis may present as a renal syndrome only, without any of the other manifestations of SLE. Renal involvement in SLE is common, but this does not necessarily indicate a poor short-term prognosis. In the Peter Bent Brigham Hospital series a sustained raised blood pressure and the onset of renal insufficiency influenced the prognosis adversel

ISSN:1660-8151    

DOI:10.1159/000179349

出版商:S. Karger AG    

年代:1964

数据来源: Karger

ISSN:1660-8151    

DOI:10.1159/000179350

出版商:S. Karger AG    

年代:1964

数据来源: Karger

ISSN:1660-8151    

DOI:10.1159/000179351

出版商:S. Karger AG    

年代:1964

数据来源: Karger

ISSN:1660-8151    

DOI:10.1159/000179768

出版商:S. Karger AG    

年代:1969

数据来源: Karger

ISSN:1660-8151    

DOI:10.1159/000179346

出版商:S. Karger AG    

年代:1964

数据来源: Karger