1. |
URINARY AND SERUM AMINO‐ACID STUDIES IN PREMATURE AND FULL TERM NEONATES |
|
Journal of Paediatrics and Child Health,
Volume 4,
Issue 1,
1968,
Page 1-7
ELIZABETH THOMPSON,
ROSEMARY LINDOP,
G. TASMAN JONES,
R. N. HOWIE,
W. D. TROUGHTON,
Preview
|
PDF (455KB)
|
|
摘要:
SYNOPSISUrinary and serum amino‐acid patterns were studied in 56 premature and full‐term babies by a new technique of combined electrophoresis and chromatography. A changing pattern of urinary amino‐acid excretion with increasing maturity was found, particularly with the basic amino acid lysine and with cystine. We have confirmed previous reports of high excretion of proline and hydroxyproline in infants. High levels of tyrosine in the blood and urine in 4 of the 37 premature babies were possibly due to a combination of high protein intake and late maturation of the enzyme tyrosinase in these infants.The excretion of glutamine was surprisingly low. Possible explanations for this are discussed.Homocitrulline was found in blood and urine of all infants fed with sterilized milk, including breast milk. This is thought to be related to the heating of the milk.Apart from tyrosine and homocitrulline, the pattern of serum amino acids did not differ significantly from that seen in normal adults.Infants malnourished in utero showed amino‐acid patterns which resembled those of babies of similar birthweight rather than similar m
ISSN:1034-4810
DOI:10.1111/j.1440-1754.1968.tb01722.x
出版商:Blackwell Publishing Ltd
年代:1968
数据来源: WILEY
|
2. |
PANCREOZYMIN ‐ SECRETIN TEST OF EXOCRINE PANCREATIC FUNCTION IN CYSTIC FIBROSIS AND THE SIGNIFICANCE OF THE RESULT FOR THE PATHOGENESIS OF THE DISEASE* |
|
Journal of Paediatrics and Child Health,
Volume 4,
Issue 1,
1968,
Page 8-22
B. HADORN,
PATRICIA G. JOHANSEN,
CHARLOTTE M. ANDERSON,
Preview
|
PDF (998KB)
|
|
摘要:
SYNOPSISPancreozymin‐secretin tests were performed on 10 children with cystic fibrosis of the pancreas, who did not show any clinical symptoms of exocrine pancreatic insufficiency. The results indicate that in this particular group of patients water and bicarbonate secretion from the pancreas is more severely affected by the disease than enzyme secretion. Thus these patients secrete a small amount of pancreatic juice with a very low bicarbonate content but an abnormally high concentration of enzymes.Based on these results, a hypothesis for the pathogenesis of cystic fibrosis is put forward using the concept that in most exocrine glands, 2 different types of secretion contribute to the final secretory product: a highly concentrated secretion of organic substances and a more dilute secretion containing mainly electrolytes. During the secretory process, the organic constituents of the first type of secretion are diluted by the electrolyte‐containing fluid of the second secretion. Evidence is presented, that the pathological features in the pancreas in cystic fibrosis could result from the failure to produce an adequate amount of electrolyte‐containing fluid and it is suggested that the changes occurring in other organs affected by the disease may result from a similar pheno
ISSN:1034-4810
DOI:10.1111/j.1440-1754.1968.tb01723.x
出版商:Blackwell Publishing Ltd
年代:1968
数据来源: WILEY
|
3. |
TREATMENT OF JAUNDICE OF IMMATURITY WITH CORTICOTROPHIN A CONTROLLED TRIAL* |
|
Journal of Paediatrics and Child Health,
Volume 4,
Issue 1,
1968,
Page 23-28
R. N. HOWIE,
Preview
|
PDF (378KB)
|
|
摘要:
SYNOPSISTreatment of infants with jaundice of immaturity by means of corticotrophin has been investigated by a controlled trial in 136 babies of low birth weight. In the particular conditions of the trial, cortiootrophin appeared to do little good but no harm.
ISSN:1034-4810
DOI:10.1111/j.1440-1754.1968.tb01724.x
出版商:Blackwell Publishing Ltd
年代:1968
数据来源: WILEY
|
4. |
THE RELATIONSHIP BETWEEN BIRTH WEIGHT AND GESTATIONAL AGE IN AN AUSTRALIAN HOSPITAL POPULATION |
|
Journal of Paediatrics and Child Health,
Volume 4,
Issue 1,
1968,
Page 29-37
W. H. KITCHEN,
Preview
|
PDF (534KB)
|
|
摘要:
SYNOPSISThe neonate whose birth‐weight diverges widely from the average for the period of gestation is subject to special hazards. Acceptable local standards of weight are required to identify these infants at risk. A chart of intrauterine weight, based on data from 2637 patients, is presented together with details of the hospital population and the methods used in selecting the patients. The influence of certain complications during pregnancy is briefly discusse
ISSN:1034-4810
DOI:10.1111/j.1440-1754.1968.tb01725.x
出版商:Blackwell Publishing Ltd
年代:1968
数据来源: WILEY
|
5. |
A DIFFICULTY IN CONFIRMING 21 HYDROXYLASE DEFICIENCY IN A NEONATE WITH CONGENITAL ADRENAL HYPERPLASIA |
|
Journal of Paediatrics and Child Health,
Volume 4,
Issue 1,
1968,
Page 38-46
B. T. RUDD,
O. M. GALAL,
R. G. McARTHUR,
Preview
|
PDF (1371KB)
|
|
摘要:
SYNOPSISThe pattern of steroid excretion of a female infant with congenital adrenal hyperplasia was examined on the fifth day of life.The absence of pregnanetriol and the pattern of steroid excretion indicated a 3β‐ol‐de‐hydrogenase deficiency; DHA and other androgens were excreted as sulphate (solvolysable) conjugates. On the other hand, the presence of 11‐oxygenated steroids in the urine did not support this diagnosis. The detection of significant quantities of reducing steroids excreted as sulphate conjugates, suggested that either the corticosterone or cortisol pathway was partially open.An ACTH stimulation test at 3 1/2 months of age while the patient was receiving dexamethasone, revealed significant quantities of pregnanetriol in the urine, and a decrease of those steroids excreted in the neonatal period. It is suggested that the ACTH test is a valuable aid in the post neonatal period in the diagnosis of difficult cases of congenital adrenal hyp
ISSN:1034-4810
DOI:10.1111/j.1440-1754.1968.tb01726.x
出版商:Blackwell Publishing Ltd
年代:1968
数据来源: WILEY
|
6. |
THE INVESTIGATION OF DISORDERS OF CALCIUM METABOLISM IN CHILDHOOD |
|
Journal of Paediatrics and Child Health,
Volume 4,
Issue 1,
1968,
Page 47-59
D. A. McCREDIE,
I. P. McINTYRE,
Preview
|
PDF (1091KB)
|
|
摘要:
SYNOPSISTests used in the investigation of Ca metabolism are discussed and the techniques and precautions described in some detail. A brief account is given of the conditions studied and of how these tests have proved useful in diagnosis and management. Particular reference is made to the use of blood and urine levels, Ca absorption studies, intravenous infusion of Ca and of bone biopsy.
ISSN:1034-4810
DOI:10.1111/j.1440-1754.1968.tb01727.x
出版商:Blackwell Publishing Ltd
年代:1968
数据来源: WILEY
|
7. |
THE SIGNIFICANCE OF ABNORMAL GLUCOSE TOLERANCE IN CHILDHOOD* |
|
Journal of Paediatrics and Child Health,
Volume 4,
Issue 1,
1968,
Page 60-65
J. M. COURT,
Preview
|
PDF (462KB)
|
|
摘要:
SYNOPSISThis paper refers to 13 children who were found to have glycosuria on routine testing of urine, but who had no symptoms referable to diabetes. Each child had one or more abnormal glucose tolerance tests on initial testing, but further observations revealed continuing glucose in only 1 child, and normal glucose tolerate in all those retested.The significance of abnormal glucose tolerance ni children without symptoms referabale to diabetes, is discussed. Treatment appropriate to diabetes mellitus is not recommended in the absence of clinical symptoms and with only the evidence of one abnormal glucose tolerance test. Further observations during succeeding months should first be made.
ISSN:1034-4810
DOI:10.1111/j.1440-1754.1968.tb01728.x
出版商:Blackwell Publishing Ltd
年代:1968
数据来源: WILEY
|
8. |
THE USE OF A MEDIUM CHAIN TRIGLYCERIDE DIET IN CHYLOPERITONEUM |
|
Journal of Paediatrics and Child Health,
Volume 4,
Issue 1,
1968,
Page 66-68
M. GRACEY,
PATRICIA M. GOOCH,
Preview
|
PDF (229KB)
|
|
摘要:
SYNOPSISThe use of a medium chain triglyceride diet in a child with tuberculosis and chyloperitoneum is reported for the first time. The rationale and apparent therapeutic success of the diet are discussed.
ISSN:1034-4810
DOI:10.1111/j.1440-1754.1968.tb01729.x
出版商:Blackwell Publishing Ltd
年代:1968
数据来源: WILEY
|
9. |
BACTERIAL ENDOCARDITIS DUE TO MORAXELLA LACUNATA |
|
Journal of Paediatrics and Child Health,
Volume 4,
Issue 1,
1968,
Page 69-72
A. S. HEWSTONE,
PHOEBE EDWARDS,
Preview
|
PDF (274KB)
|
|
摘要:
SYNOPSISA case of bacterial endocarditis due toMoraxellalacunata is presented. The characteristics and method of identification of the organism are described.
ISSN:1034-4810
DOI:10.1111/j.1440-1754.1968.tb01730.x
出版商:Blackwell Publishing Ltd
年代:1968
数据来源: WILEY
|
10. |
A NEURO‐DEVELOPMENTAL APPROACH TO THE TREATMENT OF CEREBRAL PALSY A PRELIMINARY REPORT* |
|
Journal of Paediatrics and Child Health,
Volume 4,
Issue 1,
1968,
Page 73-77
CORRIE REYE,
Preview
|
PDF (1136KB)
|
|
摘要:
SYNOPSISAn attempt has been made to assess the value of a neuro‐developmental approach in the treatment of children with cerebral palsy. Some‘facilitation’techniques used to encourage automatic postural reactions are mentioned and it is emphasized that these patterns are more easily established in the very young before the increased tone or fluctuation of tone has become well establ
ISSN:1034-4810
DOI:10.1111/j.1440-1754.1968.tb01731.x
出版商:Blackwell Publishing Ltd
年代:1968
数据来源: WILEY
|