摘要:

Forty-five consecutive patients treated for postherpetic neuralgia (PHN) at the UCLA Pain Management Center were studied. Demographic data, the Minnesota Multiphasic Personality Inventory (MMPI), psychological symptoms, Beck Depression Scale, McGill Pain Questionnaire (MPQ), and a Visual Analogue Scale (VAS) of pain intensity were examined as predictors of treatment outcome from a multimodal pain management program. Age was the only pretreatment variable positively related to outcome.

ISSN:0749-8047    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

A patient-controlled device for administration of 50% nitrous oxide in oxygen (Nitronox®) was used by 28 children and young adults with cancer aged 8–27 years during 40 painful diagnostic procedures. The pain experienced by 26 evaluable patients, as measured by a visual analogue scale (VAS), was significantly reduced compared to the pain experienced by 16 patients during a previous, identical painful procedure without nitrous oxide (p < 0.01 Wilcoxon 1 -sample test). Although patient-related toxicity was minimal, high levels of occupational exposure to nitrous oxide were documented during the five procedures in which room air levels were monitored.

ISSN:0749-8047    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

The effectiveness of intravenous lidocaine for relief of vascular headache was assessed using a single-blind protocol. Patients with acute pain due to common migraine or cluster headache were studied and compared with patients with cranial pain of other causes. Pain intensity was measured using a visual analog scale. In 13 headache patients, an intravenous injection of lido- caine (100 mg standard dose) produced rapid relief of clinical pain, with an associated significant change in visual analog scale scores (p < 0.001). Relief lasted approximately 20 min; in most patients the pain then returned to pretreatment levels. No significant side effects were reported by the subjects. This response may be the result of a direct, anesthetic action of lidocaine on trigeminal nociceptive afferents innervating cranial blood vessels.

ISSN:0749-8047    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

There are conflicting reports in the literature on the effects of age on temporomandibular joint pain. A multivariate analysis was performed to determine the effect of age on clinical presentation, findings, and management of a consecutive series of patients with this common condition. These factors were compared with a matched control group. It was found that age had little effect on the clinical signs and symptoms, radiologic findings, or outcome of treatment. There was an increased loss of teeth and occlusal support but this was similar between the control and experimental groups. There were clear differences with psychological variables between the groups with different ages and in comparison with controls. The increase in life events and abnormal illness behavior with increasing age seemed closely linked to patients seeking treatment.

ISSN:0749-8047    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

The co-occurrence of chronic low back pain and headache was examined in a sample of 227 patients referred to a multidisciplinary pain treatment program. Over 60% of the patients who reported chronic low back pain also reported concomitant headache, although only 24.8% of these patients reported a history of headache prior to the onset of low back pain. Discriminant analysis performed on a random half of the subject sample (n = 119) indicated that chronic low back pain patients with concominant headache dif- fered significantly from pain patients without headache on Minnesota Multi- phasic Personality Inventory (MMPI) scales hypochondriasis (Hs), depression (D), hysteria (Hy), and overall impairment as measured by the Sickness Im- pact Profile. Twenty percent of the variance in the discriminant scores was attributable to the difference between groups. Approximately 65% of the cases were classified correctly based upon the discriminant function scores, which was replicated on the remaining subsample of patients (n = 108). There was no significant difference in behavioral pain treatment outcome between patients with vs. without headache.

ISSN:0749-8047    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

A simple method using behavioral characteristics is presented for identifying chronic benign pain patients who will require referral for psychosocia1 and/or psychological evaluation at the time of the initial consultation visit.

ISSN:0749-8047    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

The effect of the addition of 0.5 mg naloxone on the analgesic em- cacy of pentazocine 50 mg was studied. A single oral dose of either pentazo- cine, the combination of pentazocine plus naloxone, or placebo was given in a randomized double-blind parallel group study. The study sample consisted of 48 patients with moderate pain and 76 patients with severe pain resulting from episiotomy, cesarean section, or gynecological surgery. An analysis of the entire sample showed both pentazocine and the combination to be significantly more effective than placebo for all measures, including global assessments. In addition, the combination was significantly less efficacious than pentazocine for the sum of the pain intensity difference (SPID), percentage of the sum of the pain intensity difference (%SPID), and for relief and pain intensity difference (PID) at the fourth hour. Because there was a significant interaction between drug and baseline pain intensity for the variable SPID, comparisons were made between pentazocine and the combination within each baseline pain intensity group. For patients with moderate baseline pain, the combina- tion produced significantly less pain relief than pentazocine for SPID and for relief and PID at hours 3 and 4. In patients with severe baseline pain, there was no significant difference between pentazocine and the combination of pentazo- cine plus naloxone. Further studies are needed to confirm the suggestion that naloxone taken orally may decrease the analgesia achieved with pentazocine; clinicians should be aware of this possibility.

ISSN:0749-8047    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

The effect of chronic disability on a family may be underestimated. A case of ctmmic pain is present & and spousal actwkyrelated to thee & the patient is reported in a quantitative manner. Adverse psychological consequences are noted in all family members.

ISSN:0749-8047    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

The current study evaluated a multidisciplinary pain management center. Thirty-eight patients with disabling chronic pain (mainly low back or head/neck/upper back pain) were interviewed before admission to the pain center and again during an 18–27 month follow-up to assess treatment out- come. Patients participating in the 3-week inpatient/outpatient program learned a variety of physiological and psychological methods of pain control. Results showed statistically significant reductions in (a) addictive medications, (b) subjective pain ratings, (c) the number of functional activities that cause pain, and (d) the number of visits to health-care professionals. The number of patients who returned to work and the implications of both time-loss compensation and the number of months since last employed are discussed.

ISSN:0749-8047    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

GABA (γ-amino butyric acid) is the major inhibitory transmitter in the central nervous system. THIP (4,5,6,7-tetrahydroisozazole(5,4c) pyridine-3–01) is a structurally rigid GABA-mimetic drug. In a single-blind trial, THIP, administered in a single oral dose to patients suffering from chronic, nonmalignant pain, was found to exert a definite analgesic effect compared with placebo (p < 0.05). The analgesic effect did not improve following a 2.5− fold increase in dose, and the side effects (dizziness, sedation, and nausea) were dose dependent and more frequent at high serum concentrations. There was no correlation between THIP serum concentration and analgesic effect. The study shows that THIP in a dose of about 0.1 mdkg body weight might be used in the treatment of chronic pain, but the therapeutic range is very narrow.

ISSN:0749-8047    

出版商:OVID    

年代:1988

数据来源: OVID