摘要:

AbstractIn the present review emphasis is placed on the description of advances made in the synthesis and biosynthesis of labelled neutral lipids as well as phosphatides and other complex ionic lipids. Methods applicable to the analysis and purification of these compounds are described briefly. In addition observations related to the autoradiolysis of labelled lipids during storage are discussed.

ISSN:0022-2135    

DOI:10.1002/jlcr.2590040102

出版商:John Wiley&Sons, Ltd.    

年代:1968

数据来源: WILEY

摘要:

AbstractEs wird die Herstellung von β‐Chloräthyl‐trimethylammoniumchlorid (Methyl‐14C) = CCC‐(Methyl‐14C) und CCC‐1,2‐14C beschrieben. Das Verfahren zur Markierung der CH3‐Gruppe ist gegenüber bereits bekannten durch seine Einfachheit ausgezeichnet. Für die Markierung der beiden CH2‐Gruppen des CCC gingen wir von Athylenoxyd‐1,2‐14C aus. Die Ausbeuten betrugen in beiden Fällen, auch betreffend die eingesetzte Aktivität, über 90 %. Die Aktivitätsmessung wurde nach katalytischer Verbrennung zu CO2in Gaszählrohren im Proportionalbereich ausgeführt. Es wird die Reinigung und Prüfung der radiochemischen Reinheit der e

ISSN:0022-2135    

DOI:10.1002/jlcr.2590040103

出版商:John Wiley&Sons, Ltd.    

年代:1968

数据来源: WILEY

摘要:

AbstractLe chlorure de deutérium a été préparé à partir d'eau lourde et de chlorure de benzoyle avec un rendement de 90 % et une pureté isotopique pratiquement identique à celle de l'eau lourde de départ. Deux problèmes annexes sont traités : une relation est établie entre la teneur en poids de DCl dans la solution et la normalité de celle‐ci. Les conditions du dosage de traces d'acide benzoïque dans DCl ont

ISSN:0022-2135    

DOI:10.1002/jlcr.2590040104

出版商:John Wiley&Sons, Ltd.    

年代:1968

数据来源: WILEY

摘要:

AbstractThree isotopically enriched samples of cyclobutene have been prepared, namely, a mixture containing 20 % [1‐13C]cyclobutene, 20 % [3‐13C]cyclobutene and 60 % parent molecule; a second mixture of 75 % [1‐D]cyclobutene and 25 % parent molecule; and a third mixture of 50 % [3‐D]cyclobutene and 50 % parent molecule. Proton magnetic resonance and infrared spectra showed the samples to be of high purity (>95 %). The preparations successfully have been used for high‐resolution microwave studies. The observed microwave line intensities also agreed with the percentage compositions gi

ISSN:0022-2135    

DOI:10.1002/jlcr.2590040105

出版商:John Wiley&Sons, Ltd.    

年代:1968

数据来源: WILEY

摘要:

AbstractA recoil labeling method for the production of propanol‐2,3‐14C1and other simple alcohols is described. In addition propanol‐2,3‐14C and 2‐methyl propanol‐3‐14C were prepared by the irradiation of methanol solutions of ethylene‐14C and propene‐1‐14C, respectively, in „scavenger”︁ concentration. This latter approach called selectiveradiation labeling is explored as a method for the preparation of specifically labeled compounds by „non‐synthetic”︁ methods. The advantages of selective radiation labeling are : 1. specificity of label; 2. ready control of desired specific activity; 3. efficient use of the labeling isotope in an appropriate precursor; 4. ease of purification and isolation of products; 5. minimum labor. Any source of penetrating radiation can be use

ISSN:0022-2135    

DOI:10.1002/jlcr.2590040106

出版商:John Wiley&Sons, Ltd.    

年代:1968

数据来源: WILEY

摘要:

AbstractA novel synthesis of tritiated compounds is reported using the direct irradiation of an aromatic‐aliphatic mixture, one of the components of which is labelled with tritium. The irradiation of the methanoltritiated benzene system has been used to illustrate the principle of the technique. The gamma irradiation of methanolic solutions of tritiated benzene yields the following tritiated scavenging products, some of which are specifically labelled under certain conditions : anisole; 1,3 –‐ and 1,4‐cyclohexadienes; 2,5‐phenylcyclohexadiene; 1,3‐ and 1,4‐cyclohexadiene‐methanols. The potential of the method as a general tritium labeling tool is discussed and compared with conventional procedures. Although the absolute yields of the labelled products from direct irradiation are small for relatively large total radiation doses (megarads), scavenging by non‐labelled parent material can be used to give large chemical yields if required. The predominant advantage of the present method is that compounds labelled in specific positions with tritium can be obtained in a one‐step chemical process whereas this synthesis may be difficult by other conventiona

ISSN:0022-2135    

DOI:10.1002/jlcr.2590040107

出版商:John Wiley&Sons, Ltd.    

年代:1968

数据来源: WILEY

摘要:

AbstractBis(tri‐n‐butyl)tin‐113 oxide was prepared from tetrabutyltin and tin‐113 tetrachloride by redistribution reaction between alkyl groups, with the formation of the intermediate tri‐n‐butyltin‐113 chloride, which was hydrolyzed to form the desired product. Purification of the reaction mixture by alumina column chromatography, followed by thin layer chromatography, revealed a pure sample. The sample was also distilled under vacuum as a further check on the efficiency of the purification methodology; radioactivity resided in the bis(tri‐n‐butyl)tin oxide fraction. Infra‐red analysis of similarly prepared non‐radioactive sample showed the SnOSn bond; the spectra agreed with published spectra, and with the spectra obtained in our laborator

ISSN:0022-2135    

DOI:10.1002/jlcr.2590040108

出版商:John Wiley&Sons, Ltd.    

年代:1968

数据来源: WILEY

摘要:

AbstractThe Wittig synthesis has been used to prepare conveniently carbon‐14 labeled 1‐olefins in the C5to C8range in about 60 % yield. The chemical and radiochemical purities of the products exceeded 99.5 %. The common source of carbon‐14 in these reactions was methyl‐14C‐triphenylphosphonium iodide which was readily and quantitatively prepared from commercially available methyl

ISSN:0022-2135    

DOI:10.1002/jlcr.2590040109

出版商:John Wiley&Sons, Ltd.    

年代:1968

数据来源: WILEY

摘要:

AbstractNon‐linear interactions between solvent and solute are observed in the radiolysis of binary organic mixtures. The use of labelled molecules to diagnose both the nature of the excited solvent species and also the nature of the interaction between these excited secties and the solute molecules will be described.The particular systems discussed in detail will be: 1. cyclohexane +14C‐benzene; 2. tritiated cyclohexane +14C‐benzene; 3. tritiated cyclohexane + benzoquinone; 4. tritiated cyclohexane + cyclopentene; 5. cyclohexane +14C‐cyclohexene; 6. cyclohexane or cyclohexane d12+ benzene or benzene‐d6; 7. cyclohexane‐d12+ cyclopentane; 8. various mixture of cyclohexane, cyclopentane and deuterated analogs with corresponding olefins and the deuterated olefins; 9. mixtures of light and heavy water vapor with cyclopentane, methane, cyclohexane and other hydrocarbons.Analysis of the products obtained in the irradiation of these systems has been informative about the nature of the quenching and scavenging processes wich take place and also about the nature of the, reactive speci

ISSN:0022-2135    

DOI:10.1002/jlcr.2590040110

出版商:John Wiley&Sons, Ltd.    

年代:1968

数据来源: WILEY

摘要:

Abstractm‐hydroxy‐α‐oximinopropiophenone was hydrogenated by tritium gas in the presence of Pd on carbon catalyst. The crude product was chromatographed on a cation‐exchange column. Two major peaks were obtained. Subsequent radio‐paper chromatography revealed that these peaks were identical with metaraminol and α‐methyl‐m‐tyramine respectively. When 3,4‐dibenzyloxy‐α‐oximinopropiophenone was used as starting material both erythro and threo α‐methylnoradrenaline as well as α

ISSN:0022-2135    

DOI:10.1002/jlcr.2590040111

出版商:John Wiley&Sons, Ltd.    

年代:1968

数据来源: WILEY