ISSN:0951-7367    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

An earlier announcement of linkage between schizophrenia and a marker on chromosome 5 has not been confirmed. Failures to replicate linkage results, both in schizophrenia and in manic-depressive illness, have led to reflection by psychiatric geneticists about the power of linkage analysis in complex disorders like schizophrenia. Including phenotypes associated with schizophrenia, such as eye movement disorders, attentional abnormalities, and event-related EEGs, may increase the feasiblity of linkage analysis

ISSN:0951-7367    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

Evidence is accumulating that scalp electrical activity can provide knowledge about the way in which the brain processes information. Deciphering the significance of abnormal brain waves in schizophrenia remains an important scientific goal, with implications for current explanatory models of schizophrenia, as well as for future clinical application

ISSN:0951-7367    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

Recent brain imaging studies in the psychoses outlining developments in our understanding of both structural and functional abnormalities are reviewed. Emphasis is placed on methodological issues that complicate this area of research while attention is drawn to the most promising technologies

ISSN:0951-7367    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

There is hope that the distinction between positive and negative symptoms in schizophrenia will provide useful etiologic, therapeutic, and prognostic information. The current status of the concept of negative symptoms is reviewed

ISSN:0951-7367    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

This paper reviews the literature on social environment and social functioning in the progression and treatment of schizophrenia. Specific aspects of social environment affecting response to treatment and long-term outcome are examined, and various treatment models aimed at improving negative symptoms and developing social skills considered

ISSN:0951-7367    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

The most important development in the treatment of schizophrenia has been that of remoxipride as a new neuroleptic drug. There are also interesting developments with other new drugs, with targeted versus continuous maintenance treatment, and with drug side-effects

ISSN:0951-7367    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

Research over the past several years has contributed to our understanding of the clinical factors associated with the development of the neuroleptic malignant syndrome, expanded our knowledge of the effectiveness of treatments for the disorder and provided further clues regarding its pathophysiology. Heightened clinical awareness of the risk of neuroleptic malignant syndrome and prompt treatment of other neuroleptic-induced side-effects may serve as the best preventative measures

ISSN:0951-7367    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

Through a review of the recent literature, evidence supporting the heterogeneity of tardive dyskinesia is presented. Risk factors include older age, negative symptoms, an affective diagnosis and cognitive impairment. Young men appear to be at greater risk for severe tardive dyskinesia. Studies examining neurotransmitter abnormalities support an etiologically heterogenous syndrome with multiple neurochemical aberrations

ISSN:0951-7367    

出版商:OVID    

年代:1991

数据来源: OVID

摘要:

The research since last year points strongly in the direction of the possibility that several psychotic disorders, other than schizophrenia and major affective disorders, will respond to specific treatment; especially the use of pimozide and imipramine in delusional disorders. Also, in the areas of post-partum psychiatric disorder, the possibility of the use of hormone treatment has emerged in several studies

ISSN:0951-7367    

出版商:OVID    

年代:1991

数据来源: OVID