摘要:

SummaryThe authors relate the results of S. D. A. of Proteins measurements in about 400 subjects.The technic of the measurements and the expression of the results are the objects of a critical examination.Measurements were made in consecutive series on 3 patients.With the technics used, normal patients show a S. D. A. value varying from 6 to 14 for women, from 10 to 18 for men.An abnormal low value was found in severe diabetes insipidus, in severe hypothyroïdism in the adult, in the adiposogenital syndrome of diencephalic origin.There is an obvious increase of S. D. A. values in hyperthyroïdism and its sympathicotonic sequels. These values are not related to basal metabolic rate, but to the neurotonic manifestations.In Simmond’s disease, in pseudo-syndrome of Simmonds, which is accompanied by functional pituitary insufficiency, and in pituitary sterility, there is also an important depression, even an absolute lack of the S. D. A. of proteins.In the so called«pituitary type»of obesity, in water and salt obesity, in pituitary thinness, in psychasthenia, the average values are obviously under the normal.We never noted an abnormal increase, neither in gigantism, nor in acromegaly, where pituitary hyperactivity may be incriminated.In cases of menopause with endocrinologic troubles and in cases of castration, where the hypophysis equally shows an intense hyperactivity, the S.D. A. rates are normal or low.Thyroïd extracts raise the S. D. A. rate but in certain cases, rest, high food supply and pituitary gonadotrophic extracts, may have the same effect. Under treatment, the S. D. A. rate rises when the nutritional or endocrinologic or nervous or psychic state of the patient improves.In conclusion, the S. D. A. of proteins does not seem to be directly influenced by the various pituitary hormones, the thyreotrophic, gonadotrophic, diabetogenic or growth hormones.The measurement of the S. D. A of proteins is not a test of deficient or excessive activity of the hypophysis. It reflects the functional state of the automatic nervous system, i.e. of a coplex apparatus influenced by the endocrines.

ISSN:1784-3286    

DOI:10.1080/17843286.1952.11717195

出版商:Taylor&Francis    

年代:1952

数据来源: Taylor

摘要:

SummaryCoagulation-time is the best way to watch the treatment with heparin. The best method seems to be that of Lee-White. Usual methods using capillary tubes or glass plates must he avoided. Prothrombine time cannot be used in control of patients treated with heparin.Such a control may be omitted when heparin is given intravenously every four hours ; When the drug is associated to some kind of solvant in order to delay its effect, the coagulation-time must be frequently checked, not to avoid over-dosage, but to warrant a sufficient administration of the drug.

ISSN:1784-3286    

DOI:10.1080/17843286.1952.11717196

出版商:Taylor&Francis    

年代:1952

数据来源: Taylor

摘要:

SummaryAuthor reviews the most characteristic features of chronic pancreatitis and discusses the treatment; reduction of the volume of meals and measures to avoid stasis in the bowels (prostygmin for instance) are useful. Novocaïn may be used in order to reduce pain. Surgery seems less and less opportune. The acute phase of the disease requires more severe dietetical measures. Food has to he avoided; glucose I. V. injections, protein hydrolysates or saline solutions must be given for 3 to 6 days. Thereafter milk with alcaline solutions may be given again by mouth. At last, the diet is enlarged according to the pain and to the decrease of serum or urinary amylases.

ISSN:1784-3286    

DOI:10.1080/17843286.1952.11717197

出版商:Taylor&Francis    

年代:1952

数据来源: Taylor

摘要:

SummaryAt least subjective results are obtained in patients with epithelial tumors by Use of thiodiglycol, a product of hydrolysis of dichlorethyl sulfur.In some cases a decrease of the size of the tumor has been observed.Thiodiglycol does not have the toxic properties of Nitrogen mustard. It does not act as a poison of the cell nor as a mitotic poison and does not influence systemic tumors such as lymphona, leukemia.The mode of action of thiodiglycol is rather hypothetical. May be it increases the sensitivity of neoplasic tissue to some other therapeutic agents or to some hormonal component concerned in anticancerous defense.

ISSN:1784-3286    

DOI:10.1080/17843286.1952.11717198

出版商:Taylor&Francis    

年代:1952

数据来源: Taylor

摘要:

Summary1. The decrease of the average bleeding time studied by Prof. Roskam and the increase of the clotting power of the blood after intravenous or intramuscular injection of thrombin allow to consider thrombin as a powerful product in hemorrhagic states.2. The absence of incoagulability after defibrination and the absence of intravascular thrombosis with normal doses of thrombin allow its use by parenteral way.3. The horsethrombin has not yet caused any immunity accident. It is not necessary to use human thrombin which is much more expensive.4. The intravenous injection of average doses of thrombin is an emergency therapy. Certain technical precautions (use of two needles and slow injection) should be taken. These are not necessary in case of intramuscular injection.5. Those injections have not any utility in case of afibrinogemia or fibrinopenia.

ISSN:1784-3286    

DOI:10.1080/17843286.1952.11717199

出版商:Taylor&Francis    

年代:1952

数据来源: Taylor

摘要:

SummaryTreatment of rheumatoid arthritis with testosterone propionate or with∆5-pregnenolone associated to vitamin C at high dosage has provided some excellent results, almost in those cases treated with testosterone. Although in most cases these therapeutics were not beneficial.These results do not answer any theoretical question; they rather put new problem in the field of antirheumatoid action of steroids.

ISSN:1784-3286    

DOI:10.1080/17843286.1952.11717200

出版商:Taylor&Francis    

年代:1952

数据来源: Taylor

摘要:

SummaryA case of a 63 years patient presenting since 1944 subcutaneous nodosities of benign appearance (and as well as simultaneously) enlarged lymph nodes, is reported. The diagnosis of lymphosarcomatosis ensued microscopic study of the lesions in 1947. The disease had led to a pronounced cachectic state that let foresee a fatal issue.The administration of 21 mgr of dichlorene (chlorhydrate of methyl-bis-β-chlorethylamin) was followed by true resurrection, with complete regression of cutaneous tumours and lymph nodes.From the pathological point of view, the biopsies performed at the last hospitalization showed a lesion whose aspect was that of a very peculiar granuloma, with marked reticular hyperplasia and some giant colls, but without necrotic reaction.

ISSN:1784-3286    

DOI:10.1080/17843286.1952.11717201

出版商:Taylor&Francis    

年代:1952

数据来源: Taylor

摘要:

SummaryThe authors report the case of a cystic cerebellar abcess, treated by radical surgical removal. A spectacular disappearance of all symptoms followed within 48 hours.The authors emphasize the importance of perifocal edematous reactions in cases of posterior fossa abcess. This edema entails most often a fatal issue, before encapsulation could possibly take place. According to the authors, the diffuse aspect of the lesion can be ascribed partly to its position.The actual use of antibiotics in unquestionably favourable to the encapsulation of these spontaneously diffuse lesions.

ISSN:1784-3286    

DOI:10.1080/17843286.1952.11717202

出版商:Taylor&Francis    

年代:1952

数据来源: Taylor