ISSN:1784-3286    

DOI:10.1080/17843286.1994.11735707

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

摘要:

SummaryA 67-year-old woman was admitted in hypoglycemic coma, with fever and signs of hyperthyroidism. Diagnosis was made of both an insulinoma and subacute (“De Qucrvain”) thyroiditis. This rare coincidence of two diseases with opposite effects on serum glucose levels, offered a rare opportunity to study glucose metabolism in this peculiar physiopathological situation. During the day abnormally high postprandial blood glucose levels were seen, pointing to the glucose intolerance usually seen in the hyperthyroid state. During the night and after prolonged fasting. however, hypoglycemia predominated, consistent with the clinical picture typical of an insulinoma. After resection of the insulinoma and spontaneous healing of hyperthyroidism, glucose metabolism reverted to normal. As shown in this case, concurrent hyperthyroidism and an insulinoma may lead to consecutive episodes of glucose intolerance and hypoglycemia within the same 24-hour period.

ISSN:1784-3286    

DOI:10.1080/17843286.1994.11718379

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

摘要:

SummaryMore than 70 years after the introduction of BCG vaccination into clinical practice many questions remain to be answered. Major trials produced conflicting results regarding the degree of protection of this vaccine against tuberculosis. Several factors which may contribute to the inconsistent results of these trials, arc discussed.In developing countries continuation of routine BCG vaccination of infants is highly recommended considering the ease of administration, low cost, wide availability and safety on the one hand and the protection provided particularly against haematogenous spread of tuberculosis on the other hand.In developed countries the vaccine is reserved for high risk groups since the prevalence of tuberculosis in the general population declined dramatically during the past decades. However, as the incidence of tuberculosis in the Western world no longer decreases steeply and indeed increases again in some countries, and because (para-) medical personnel risks to be among the prime victims of this re-emergence of tuberculosis, rigorously sustained preventive measures to protect this professional category deserve renewed interest. Among those, BCG vaccination can be considered, especially in case of a high prevalence of multidrug-rcsistant tuberculosis, but also for the Belgian situation with a high degree of non-immune health care workers. Therefore, we believe that BCG vaccination still has a future.

ISSN:1784-3286    

DOI:10.1080/17843286.1994.11718380

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

摘要:

SummaryBronchial hypcrresponsivencss is a hallmark of asthma although it can also be present, to a lesser extent, in other diseases. The level of bronchial responsiveness depends on immuno-inflammatory processes modifying the functional status of airway smooth muscle as well as the structure of the bronchial wall. The responsiveness toward a direct constricting pharmacological agent is poorly correlated to the one toward an indirect constricting agent or a physical stimulus which cause airway obstruction through a more complex mechanism. Transversal studies show a relationship between the severity of asthma and the level of methacholine airway responsiveness. Long term treatment with corticoids can reduce the bronchial hypcrresponsivencss of asthmatics.

ISSN:1784-3286    

DOI:10.1080/17843286.1994.11718381

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

摘要:

SummarySeveral years ago,Rochalimaea henselaehas emerged as an agent of bacillary angiomatosis, bacillary peliosis and recurrent septicaemia that generally occur in patients infected with human immunodeficiency virus. An aetiologic role in cat scratch disease is also suspected widely on the basis of a serologic survey. Its slow growth and its culture requirement explain that this pathogen, a gram-negative bacterium, could not be isolated until 1990. Moreover, blood and tissue samples request lysis and crushing for recovering by culture. The clinical, histological, microbiological and pathogenic aspects of these in;fcctions are described and discussed.

ISSN:1784-3286    

DOI:10.1080/17843286.1994.11718382

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

摘要:

SummaryWe report a case of lymphocytic colitis in a 74-year-old woman presenting with watery diarrhea since 1 year and in whom previous extensive investigations were normal. The diagnosis could be made on the basis of typical pathological pattern in colonic biopsies. The outcome was favourable wilh salazopy rine therapy. The clinical, histological and pathophysiological aspects of lymphocytic colitis are discussed.

ISSN:1784-3286    

DOI:10.1080/17843286.1994.11718383

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

摘要:

SummaryWe describe a patient in whom cutaneous vasculitis appeared after 4 days of ciprofloxacin administration. On clinical examination, papular and purpuric lesions were limited to the left axillary zone of the thorax. Skin biopsy did not show the classic leukocytoclastic image but rather a mononuclear infiltrate of the vessel walls. Except a mild increase in inflammatory parameters, there were neither autoantibodies nor biological abnormalities, and the complement level was normal. These findings suggest that ciprofloxacin-induccd vasculitis displays histopathological and serologic heterogeneity.

ISSN:1784-3286    

DOI:10.1080/17843286.1994.11718384

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

摘要:

SummaryA patient developed an occlusion of both renal arteries by extension of a thrombosis of the infra-renal aorta to the superior mesenteric artery. He presented with classical features of acute renal ischemia: lumbar pain, nausea, vomiting, anuria. Since surgery and intra-arterial thrombolytic therapy were not feasible, we performed two peripheral intravenous (IV) perfusions of 50 mg Recombinant Tissue-Type Plasminogen Activator (r-tPA) given at 24 hours interval. During the next month serum creatinine decreased from 8, 8 mg/dl to 2 mg/dl and the creatinine clearance rose from 0 to 20 ml/minute. The patient never required any dialysis. Seven months later his renal function remains stable.

ISSN:1784-3286    

DOI:10.1080/17843286.1994.11718385

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

摘要:

SummaryThree cases of biphenotypic CD2 or CDS positive chronic lymphocytic B-cell leukaemias are reported. This represents an incidence of 15% in the authors’scries, a frequency never mentioned previously. CD2 expression could be an example of asynchronous expression of an early pre-B antigen. CD8 expression might probe a true mixed lineage phenotype. These aberrrant phenotypes were not associated with any peculiar clinical presentation.

ISSN:1784-3286    

DOI:10.1080/17843286.1994.11718386

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1994.11718387

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor