ISSN:1784-3286    

DOI:10.1080/17843286.1989.11717978

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryThe last 105 endoscopic sphincterotomies performed between 1983 and 1987 arc evaluated and compared with the recent data of the literature. The sphincterotomy has been successful in 98 cases (93 %). The indications were: 95 cases of common bile duct stones and 10 inflammatory stenoses of the duodenal papilla. The stones have been removed in all eases of sphincterotomy for choledocholithiasis (100 % of the successful sphincterotomies, 93 % of all attempts). The morbidity rate was 5 %. There has been no need for emergency intervention. Mortality was zero. In order to obtain high success rates with endoscopic sphincterotomies and removal of stones with minimal morbidity and mortality, the procedure should be performed by in experienced operator who avoids precutting in case of difficult insertion and who makes calibrated incisions related to the volume of the stones (not larger than 2 cm). Endoscopic sphincterotomy is a safe method of treatment for choledocholithiasis and papillary stenosis. It carries a lower morbidity and mortality than surgery.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11717979

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryJn the context of a surveillance programme for infectious diseases in Belgium, a network of microbiological laboratories, since February 1983, weekly registers the isolation of a number of pathogenic agents, among whichCampylobacter.Some epidemiological characteristics ofCampylobacterin Belgium are discussed. Between 54 and 58 % of the isolations are reported from males. About 50 % of the eases arc observed in children under 5 years of age. The mean weekly number of isolations per laboratory is rising in May and remains high until October-November.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11717980

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryWe have evaluated blood viscosity parameters in 20 men suffering from coronary heart disease (CHD) and in 15 control subjects. Whole blood Vscosity at a standardized haematocrit of 45 % was significantly increased in the CHD-patients, both at low (p<0.001) and high (p<0.05) shear rate. The increased whole blood viscosity in these patients was explained by an increased Plasma viscosity (p<0.01), while the erythrocyte suspension viscosity values at a standardized haematocrit of 70 %, reflecting erythrocyte deformability, were within the normal range.We have studied the effects of a daily supplementation of 1.5 g omega-3 polyunsaturated fatty acids on blood viscosity in the CHD Patients. After 6 weeks of treatment whole blood viscosity, at low and high shear rate, and plasma viscosity were significantly improved (all p<0–05), although not normalized. There was no effect of the fish oil on erythrocyte deformability.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11717981

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryPrimary sclerosing cholangitis (PSC) and idiopathic pulmonary fibrosis (IPF) were each separately described in association with a variety of chronic idiopathic inflammatory diseases such as retroperitoneal fibrosis, Sicca complex or Riedel’s thyroiditis. We report a case which may be the first description of the association between PSC and IPF. The physiopathogenic implications of such an association are discussed.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11717982

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryEssential thrombocythemia (ET) belongs to the group of clonal myeloproliferative disorders such”as polycythemia vera (PV), chronic myelogenous leukemia (CML), and idiopathic myelofibrosis (MF). This rare disorder, characterized by an important thrombocytosis, includes a mucocutaneous hemorrhagic diathesis and thromboembolic events. Neurologic manifestations are frequent in ET and are due to obstruction of the cerebral microvasculature. Both thrombocytosis and platelet dysfunction can be responsible for the thrombo-hemorrhagic phenomena in ET. First symptoms of ET in our patient was thrombosis of the arteria vcrtebralis with a secondary embolic event in the thalamusregion although the platelet count was below 600.1071, the classic diagnostic limit for ET. These data strongly suggest that qualitative Platelet abnormalities rather than thrombocytosis are the main cause for thrombo-embolic events in ET.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11717983

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryAmyloid is a beta-pleated fibrillar protein principally constituted of light chains of immunoglobulins (fi or ft) in primary or myeloma-associated amyloidosis, of AA proteins in secondary amyloidosis and familial Mediterranean ever, and of variants of prealbumin—now called transthyretin—in senile amyloidosis and familial polyneuropathies. Other identified amyloidogenic proteins involve APUD protein derivatives (calcitonin), fi2microglobulin in chronic hemodialysis-related amyloidosis and B Protein in Alzheimer disease.After a short review of experimental findings and theories concerning the pathogenesis of amyloid deposition, the clinical aspects of amyloidosis are discussed stressing their great diversity.The diagnostic approach is also examined, with Particular emphasis on rectal and kidney biopsy and subcutaneous adipose tissue aspirates.Finally, some comments on the treatment of amyloidosis (role of colchicine and DMSO) are made.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11717984

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryA new observation of inherited factor XIII deficiency is described. The patient had presented in the past with an umbilical haemorrhage, a cerebral haemorrhage, multiple haematomas with delayed onset after minimal trauma, and episodes of spontaneous haemarthrosis. The biological diagnosis was made at the age of 7 years. The child had undetectable transamidating activity and factor XIII a chains, while the level of b chains was reduced. The values observed in the parents were intermediate between those of the patient and those of normal plasma. Heated factor VIII concentrates were found to contain only low amounts of factor XIII, and were thus unsuitable for the prophylactic therapy of this rare disease. The patient was successfully treated with monthly injections of a factor XIII concentrate.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11717985

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11717986

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11717987

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor