摘要:

AbstractA wide range of both prescription and nonprescription drugs has been reported to affect human sexual functioning. While the sexual side effects resulting from drug use have often been attributed to adrenergic, anticholinergic or dopaminergic activity, the present review considers the potential role of serotonin. Based on animal studies, serotonin has been shown to either facilitate or inhibit sexual activity depending on which serotonin receptor subtype is activated. However, few studies have been done in the human that assess the effects of drugs that bind selectively to serotonin receptors. Consequently, little is known about the role of serotonin inhuman sexual functioning. In this review, a wide range of drugs that affect both brain serotonergic systems and human sexual behavior is examined in an effort to determine the possible role of serotonin in human sexual behavior. A review of the literature is consistent with the hypothesis that the 5-HT1Aand the 5-HT2receptor subtypes play a facilitatory role in human sexual behavior. The evidence suggests that drugs that act as agonists on these receptor sites enhance sexual functioning in the human, while those that act as antagonists inhibit sexual functioning.

ISSN:0279-1072    

DOI:10.1080/02791072.1992.10471616

出版商:Taylor&Francis Group    

年代:1992

数据来源: Taylor

摘要:

AbstractNeedle exchange is a practical and important part of the Dutch prevention strategy to check the spread of HIV among injecting drug users (IDUs). However, needle-exchange programs are often tied to drug treatment programs that only reach a limited number of IDUs. To overcome this limit ation, alternative designs are considered and initiated. This article describes a community-based approach to needle exchange that is built on empowerment of, and intense participation by, known IDUs to target unknown IDUs for delivery of clean needles. The needle-exchange patterns of the IDUs participating in this collective scheme are compared to those of other users who exchanged needles on an individual basis. It was found that this approach extended the reach of the program to a great degree and that it was well received in the IOU community. However, the results were negatively influenced by police activities aimed at closing down places where drugs were used and sold. It is concluded that engaging IDUs in peer-group-directed prevention efforts is both feasible and promising.

ISSN:0279-1072    

DOI:10.1080/02791072.1992.10471617

出版商:Taylor&Francis Group    

年代:1992

数据来源: Taylor

摘要:

AbstractOdyssey House is a therapeutic community (TC) in New York City that treats a wide range of drug abusers. For over 20 years, Odyssey House has conducted an annual marathon therapy group for women who are rape survivo rs. This article summarizes the program's experience with the marathon and reports on its therapeutic accomplishments.

ISSN:0279-1072    

DOI:10.1080/02791072.1992.10471618

出版商:Taylor&Francis Group    

年代:1992

数据来源: Taylor

ISSN:0279-1072    

DOI:10.1080/02791072.1992.10471619

出版商:Taylor&Francis Group    

年代:1992

数据来源: Taylor

ISSN:0279-1072    

DOI:10.1080/02791072.1992.10471620

出版商:Taylor&Francis Group    

年代:1992

数据来源: Taylor

ISSN:0279-1072    

DOI:10.1080/02791072.1992.10471621

出版商:Taylor&Francis Group    

年代:1992

数据来源: Taylor

ISSN:0279-1072    

DOI:10.1080/02791072.1992.10471622

出版商:Taylor&Francis Group    

年代:1992

数据来源: Taylor

ISSN:0279-1072    

DOI:10.1080/02791072.1992.10471623

出版商:Taylor&Francis Group    

年代:1992

数据来源: Taylor

ISSN:0279-1072    

DOI:10.1080/02791072.1992.10471624

出版商:Taylor&Francis Group    

年代:1992

数据来源: Taylor

ISSN:0279-1072    

DOI:10.1080/02791072.1992.10471625

出版商:Taylor&Francis Group    

年代:1992

数据来源: Taylor