ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1985.tb03158.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACT –A group of 23 professional divers was investigated before and after dives to 300 and 350 metres of sea water. 12 divers were also studied during the actual dive.All divers presented neurological symptoms and signs during compression. Intention tremor, ataxia, motor weakness, sensory symptoms, vertigo, nausea and reduced memory were the most prominent features of the High Pressure Nervous Syndrome (HPNS). There were considerable individual differences. Neuropsychological and neurophysiological investigations performed after one dive showed no significant changes in any of the divers, while there was a clear‐cut impairment in a group of 6 divers who had performed 2 dives 3 months apart. These changes indicate that there may be pressure‐induced brain dysfunction which persists for a transient post‐dive period. Loss of short‐term memory is a prominent part of this dysfunction.Transitory neurological signs indicating focal cerebral dysfunction were found immediately post‐dive in 4 divers, presumably reflecting the unmasking of pre‐existing subclinical minima

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1985.tb03159.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACT –Using the results from 485 patients with various forms of cerebral dysfunctions and from 60 hospitalized controls, it was shown that measurement of continuous reaction times (CRT) is sensitive to cerebral lesions. Reaction times were more impaired by progressive than by non‐progressive brain diseases. The test did not distinguish between patients with right‐ or left‐hemisphere lesions and was not influenced either by etiology, chronicity, age or sex.Our conclusion is that CRT is useful as a “screening” test for the presence of cerebral dysfunction and is especially sensitive to progressive diseases. Its discrimination power is equivalent to more sophisticated and complex psycholo

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1985.tb03160.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACT –The present experiment compared the effects of flupentixol (0.5 mg) and relaxation on acute laboratory pain induced by pressure. Results showed that flupentixol, in general, did not have an analgetic effect, but rather a negative effect. Relaxation with specific training for the pain site did have pain‐relieving properties, while an “unspecific relaxation” control procedure did not result in significant pain relief. Possible explanations for the unexpected negative effect of flupentixol are di

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1985.tb03161.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACT –Three patients with well‐defined clinical and radiographic lesions have been studied with somatosensory evoked potentials (SSEPs). The data indicate that the primary scalp potentials from stimulation of both the arm and leg (N̄20and P̄40) can be lost with thalamic lesions and would be consistent with these potentials being generated in either the thalamus or thalamocortical radia

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1985.tb03162.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACT –A woman aged 21 with a variant form of metachromatic leucodystrophy (MLD) combined with another form of leucodystrophy is described. The clinical symptoms were retinitis pigmentosa and progressive neurological defitics such as mental retardation, dystonia, pyramidal tract involvement and peripheral neuropathy.The biochemical findings were marked deficiency of arylsulfatase‐A and cerebrosidesulfatase in cultured fibroblasts and excretion of sulfatides in the urine. Sulfatideloading of cultured fibroblasts showed almost normal uptake and degradation of sulfatides. The patient's sister suffers from a clinically similar neurological disease, but normal activity of arylsulfatase‐A was found in her leucocytes. A severe oral‐facial dystonia in the patient was successfully controlled by

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1985.tb03163.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACT –Autonomically mediated cardiovascular responses to certain manoeuvres were studied in 20 parkinson patients, 24 h off levodopa‐decarboxylase inhibitor medication and again one h after medication. Results were compared with 15 healthy control subjects. The heart rate at rest was higher in parkinson, the respiratory sinus arrhythmia was lower, while the Valsalva ratio, the heart rate and blood pressure responses during an orthostatic test and the heart rate response to a dive reflex test were normal. These findings indicate a normal function of peripheral autonomic nerves and a possible central parasympathetic dysfunction.There were significantly attenuated responses of heart rate, blood pressure and contralateral forearm blood flow to an isometric handgrip. Since the peripheral autonomic nerves seemed to be normal, these results could be related to a reduced central command and/or diminished stimulation of postulated peripheral ergoreceptors in parkinsonism.There was no major effect on the cardiovascular responses by the acutely administered medicat

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1985.tb03164.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACT –We have examined the incidence of the Guillain‐Barré syndrome (GBS) in the county of Hordaland. We have previously reported a marked increase in the incidence of MS in the same population. 109 GBS‐patients were diagnosed in the period 1957–1982 according to the criteria of NINCDS. The annual incidence rates were stable over time with an average incidence of 1.2 per 100,000 population per year. The male/female ratio was 1.7. No statistically significant difference in incidence was found between urban and rural areas. We found an increasing incidence with age, more marked among males than among females. A predilection for GBS to occur in the colder half of the year was also found. 57% of the patients reported an antecedent infection less than 4 weeks prior to the onset of neurological symptoms. The stable incidence rates for GBS over time in contrast to an increase in the incidence of MS in the same population, indicates that different pathogenetic mechanisms are important in the two demyelinating

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1985.tb03165.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACT –In 14 normal male adults and 97 male patients having impotence alone or together with systematic and/or neuro‐psychiatric symptoms and signs, the somatosensory cerebral‐evoked potentials were obtained by glans penis stimulation (penile SEP); by peroneal nerve stimulation (peroneal SEP) and by electrically‐induced bulbocavernous (BC) reflex. In normal subjects, the configurations of both SEPs were basically similar, except that the onset of latency was 10–15 msec longer and the amplitude in the P1‐N1component was higher in penile SEP. BC‐reflex latency was abnormally prolonged, especially in diabetic impotence and in patients with cauda/conus lesions, while the abnormalities on the penile and peroneal SEP were more frequent in patients with spinal cord injuries, MS and parkinsonism. In impotent patients with epilepsy, chronic prostatitis and psychogenic problems, all the tests were gen

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1985.tb03166.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACT –A major aim of this study was to determine the diagnostic value of 4 electrophysiological tests in MS, and particularly their effectiveness in detecting signs of brainstem involvement. Therefore, auditory brainstem evoked response (ABER), somatosensory evoked response (SSER), blink reflex and electronystagmographic (ENG) investigative methods were applied to a group of 89 patients with definite, probable or possible multiple sclerosis (MS).The 4 methods yielded interdependent data, especially where the brainstem function was concerned, thus it can be concluded that a single demyelinating lesion may cause a combination of electrophysiological disorders within a small structure such as the brainstem.ENG recordings were found to reveal the highest number of asymptomatic abnormalities. The combination of ABER and ENG tests revealed electrophysiological disorders in 81% of all patients. The blink reflex and the SSER tests gave hardly supplementary informatio

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1985.tb03167.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY