摘要:

The cytology of the cerebrospinal fluid (CSF) (obtained by suboccipital puncture) from patients after cardiac arrest was investigated by means of the cytocentrifugation method.In patients with unsuccessful resuscitation an increased number of monocytes and macrophages was found immediately after abandoned resuscitation.A pronounced increase in the number of granulocytes, monocytes, and macrophages was found in patients with poor neurologic restitution. the increase in the number of macrophages was seen immediately after cardiac arrest. the granulocyte increase was most pronounced after 24 h.The CSF from patients with full neurologic restitution after cardiac arrest showed small numbers of lymphocytes and granulocytes and an equal amount of monocytes and macrophages.The findings indicate that monocytes/macrophages appear in the cisternal fluid shortly after anoxic/ischemic damage to the brain and that the increase of macrophages and later granulocytes probably is a result of damage to brain tissue.

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1978.tb04493.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

The cell responses to different polyclonal lymphocyte activating substances were studied in 15 patients with aseptic meningitis by analysis of lymphocyte proliferation. thein vitroresponse to phytohaemagglutinin (PHA), concanavalin A (Con A) and poke weed mitogen (PWM) was investigated in blood and CSF lymphocytes simultaneously. the blood lymphocytes responded stronger than the corresponding number of CSF lymphocytes. These cells were, however, always capable of a response, suggesting that they were immunologically competent. No predominance of either PHA or Con A populations of T lymphocytes could be demonstrated in CSF compared to blood by this technique. When culture conditions were changed from the optimal cell or mitogen concentrations, the decrease in proliferation of the CSF lymphocytes was more pronounced than that of blood lymphocytes.

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1978.tb04494.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1978.tb07631.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1978.tb07632.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

One hundred patients with a 3rd ventricle width of 12 mm or more were examined for the fifth time in 1976 after an average observation period of 20.8 years. On first admission, a predominant aetiological factor was found in 27 cases. Two patients had air‐encephalogrophical findings indicating normal pressure hydrocephalus. One of these had a shunt operation, however, without improvement.Seventy‐one patients had died, 7 patients were in need of care and supervision, 11 patients were unable to work, the remaining 11 were able to work to some extent. the group studied had a significantly increased mortality rate. the causes of death were divided into three groups: 1. Probably related to the underlying brain disorder; 2. Related to those in an average Norwegian population; and 3. Minor disorder usually not leading to death.The following factors indicated a poor long‐term prognosis: 1. Serious associated disease; 2. A relatively high age; 3. Associated cardiovascular disease; 4. Marked degree of ventricular enlargement; 5. Marked enlargement of the temporal horns; 6. Many and/or marked neurological signs; and 7. Progressive intellectual deterior

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1978.tb04495.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1978.tb07633.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1978.tb07634.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1978.tb07635.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1978.tb07636.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

The occurrence of oligoclonal IgG and homogeneous free lambda light chains in the cerebrospinal fluid (CSF) of a patient with progressive rubella virus panencephalitis is reported. Fractions of oligoclonal IgG corresponding to those of the CSF occurred also in the serum.Evidence is presented that the oligoclonal IgG of serum and CSF represent rubella virus‐specific antibodies. Different populations of oligoclonal IgG appear to be associated with antibody specificities to different antigenic components of the viru

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1978.tb04497.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY