摘要:

During the last 10 years it has become apparent that hyperoxaluria often is present in malabsorptive states. This secondary hyperoxaluria could be explained by an increased uptake of dietary oxalate due to malabsorption of fatty acids and bile salts. Dietary prescriptions, including a low fat diet is advocated in the treatment of hyperoxaluria in Crohn’s disease or after small bowel resectio

ISSN:0042-1138    

DOI:10.1159/000280387

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

A study of the levels of urinary fibrinolytic degradation products was undertaken in patients with different stages of carcinoma of the prostate trying to detect latent fibrinolysis. No differences between the control group and patients with carcinoma were found. The search for a rapid screening diagnostic test for latent intravascular coagulation should be pursued in order to prevent possible bleeding complications in these patients.

ISSN:0042-1138    

DOI:10.1159/000280388

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

In 34 dogs the effect of a 90-min period of warm ischemia on renal perfusion and function was studied with and without (Sar1, He8) angiotensin II treatment. In the first 3 h after the release of renal arterial occlusion, a significant influence of the angiotensin II antagonist on changes in postischemic vascular resistance, intrarenal hemodynamics and renal function could be demonstrated, all being well preserved in the treated group.

ISSN:0042-1138    

DOI:10.1159/000280389

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

A new urodynamic technique, in which detrusor and bladder pressures are recorded with suprapubic percutaneous catheters, was used for investigation of 19 healthy female volunteers to obtain urodynamic reference values. The investigation was made in parous as well as in nulliparous women of varying ages. Apart from a significantly elevated premicturition pressure in the elderly women, neither age nor parity seemed to change urodynamic parameters. Voidings with three different, defined bladder volumes in each volunteer indicated that flow increased with a larger volume up to a certain limit (400 ml) but further increase of volume did not raise the flow. All total bladder pressures, maximum detrusor pressures, and detrusor pressures at maximum flow at micturitions were independent of bladder volumes. Micturitions were made as detrusor micturitions as all volunteers were requested not to strain at voiding. It is considered that detrusor micturitions must be the best way to obtain comparable parameters from different urodynamic investigations.

ISSN:0042-1138    

DOI:10.1159/000280390

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

Vasoseminal vesiculographies before and after ejaculation were compared in 16 cases of male sterility. In 12 cases the contrast medium was excreted into the ejaculate and the contours of the seminal vesicles were contracted after ejaculation. In 4 cases, however, there was little or no contraction of the seminal vesicles. Here the seminal tracts were considered to be abnormal and this dysfunction seems to be the cause or at least one of the cofactors responsible for sterility. The degree of excretion of contrast medium into the ejaculate seems to depend on the function of the seminal tract. Therefore, a postejaculation seminal vesiculogram is useful as a parameter for estimating the function of the seminal tract.

ISSN:0042-1138    

DOI:10.1159/000280391

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

In earlier experiments it has been shown that cellular cytotoxicity of patients with prostatic carcinoma (CaP) as measured by cytolysis of EB 33 target cells correlates with the extent of their tumor lesion: a high grade of cytotoxicity was observed only when CaP was confined to gland. In order to define a possible in vivo immunological host-tumor interaction, further characterization of the type of effector cell responsible for in vitro killing has been attempted. Effector cells could be either tumor-specific sensitized T cells, K cells, macrophages or NK cells. Antibody-dependent K-cell activity could most likely be excluded, since autologous and homologous serum did not affect the extent of EB 33 killing when added to the test medium. Further separation of effector cells by nylon wool columns resulted in increased cytolysis of EB 33 target cells. This can be due either to tumor-specific T-cell-mediated mechanisms or to an increased natural killer cell activity, as macrophages and B cells were significantly removed by this measure. Separation of T and NK cells is necessary to ascertain the effector cell responsible for the in vitro killing of tumor cells derived from human CaP.

ISSN:0042-1138    

DOI:10.1159/000280392

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

From a questionnaire survey dealing with urinary incontinence during pregnancy and after childbirth 62 women were randomly selected. These women underwent simultaneous urethrocystometry including urethral profile measurement 7–14 days after parturition. From the case history two groups of patients could be distinguished. One group consisted of women who experienced only occasionally urine leakage after delivery. Pressure recordings in these previous patients were normal, moreover the urethral closure pressure was positive, also at cough provocations. The urethral length and pressure were similar to that found in continent females. The other group of patients reported stress incontinence of a more serious and permanent nature; the symptoms did not disappear after delivery. In all these women negative urethral closure pressures were recorded at cough provocations and simultaneously leakage of urine from the urethra was observed. In addition the urethral length was shorter and urethral resting pressure lower than that recorded in the first group of patients. The reversible symptoms in the first group of women may be a consequence of the pressure exerted by the uterus upon the bladder at coughing combined with a hormonal relaxation of the urethral suspension. In the second group, the enduring symptoms suggest irreversible damage to the urethra and its suspension system during pregnanc

ISSN:0042-1138    

DOI:10.1159/000280393

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

In 70% of the patients with unilateral retentio testis the normal descended testicle shows damage in spermiogenesis too. The formation of auto-antibodies is considered as a possible cause. In rats with artificial uni- and bilateral cryptorchism, this mechanism was examined. The presence of auto-antibodies against spermatozoa could be proven by indirect immunofluorescence. After uni- and bilateral intra-abdominal displacement of the testicles, this phenomenon takes place after the 3rd month post-operatively, shows the maximum of titers after 6 months and decreases towards the 9th month post-operatively. An animal model is presented, suitable for the study of immunological processes in unilateral gonadal diseases.

ISSN:0042-1138    

DOI:10.1159/000280394

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

Benzilonium bromide (Ulcoban®) has been tried in oral administration in 10 healthy volunteers, 5 of whom got the substance in a fast-release form and 5 in a combination of fast- and slow-release preparation. Serum concentration analyses show that the subject after 1 week of treatment has a certain amount of active substance in blood 12 h after the last administration. There is an increase in serum concentration during the morning hours after administration of another dose at least 1 h before breakfast. The serum concentration is higher when the fast-release form is used. We found in the urodynamic investigation, after 1 week of treatment, an effect on detrusor pressures and urinary flow. In micturitions with a large initial bladder volume, when the patient more easily can initiate a micturition, the difference is not statistically significant. When the initial bladder filling is small, it is more difficult to initiate a micturition, and at an initial bladder volume of 200 ml the difference between micturition with and without benzilonium bromide is more marked, especially in urinary flow and detrusor pressures where the differences are statistically significant

ISSN:0042-1138    

DOI:10.1159/000280395

出版商:S. Karger AG    

年代:1981

数据来源: Karger