ISSN:0042-1138    

DOI:10.1159/000279836

出版商:S. Karger AG    

年代:1973

数据来源: Karger

摘要:

The ability to cut and cauterize tissue makes the laser beam to a new surgical instrument. It could be used routinely, if suitable instruments would be developed. Until now surgical procedures could be carried out only by means of direct beams or by means of articulated arms. Therefore, our experiments, regarding resection of spleen, liver and kidney, were carried out on rats and on a pig, by means of the direct CO2-beams. Amputation of the kidney pole without clamping the supplying vessels as well as resection of the liver could be demonstrated, whereas resection of the spleen was impossible. An important progress was made recently, when a fully mobile and usable light scalpel and an endoscopic light probe was constructed.

ISSN:0042-1138    

DOI:10.1159/000279837

出版商:S. Karger AG    

年代:1973

数据来源: Karger

摘要:

Trifluoroisopropyl-α-cyanoacrylate (MBR 4197), a new tissue adhesive, was studied in kidney pole amputations on rabbits and dogs. The amputation was performed with a cryo scalpel, and the opened calyces were sealed by a running suture. Then the wound surface was covered with the tissue adhesive and lyophilized amniotic tissue. A complete hemostasis was achieved in all experiments. The adhesive power of the acrylate was excellent. The isotope renogram revealed no disturbance of renal function. There was only a slight inflammatory reaction around the acrylate adhesive. The brittle adhesive film disintegrated into pieces after the 5th postoperative day. Although the final healing was satisfactory, a still more flexible and more rapidly resorbed adhesive is desirable

ISSN:0042-1138    

DOI:10.1159/000279838

出版商:S. Karger AG    

年代:1973

数据来源: Karger

摘要:

A new instrument for the investigation of concrements is described. In the case of contact between concrement and probe the high-scratch frequencies are amplified selectively. The instrument is very helpful in detecting concrements not only in the kidney but also in the whole urinary tract.

ISSN:0042-1138    

DOI:10.1159/000279839

出版商:S. Karger AG    

年代:1973

数据来源: Karger

摘要:

In preliminary animal experiments lyophilized dura was fixed with tissue adhesives to the abdominal muscular layer in order to achieve sutureless closures of laparotomies. If the whole surface of the dura was painted with adhesive, no organization occurred. If, however, the adhesive was applied in form of a grid, ingrowth of cells could be observed and a satisfactory closure of the laparotomies was achieved. Clinically, this method was applied for reinforcement of large incisional hernias after nephrectomy or prostatectomy. The edges of the hernias were approximated by single interrupted sutures and the commercially available dura was attached by a grid of adhesive, painted on the dry dura by a roller made of teflon.

ISSN:0042-1138    

DOI:10.1159/000279840

出版商:S. Karger AG    

年代:1973

数据来源: Karger

摘要:

In order to improve cryopreservation of whole organs, possible cryoprotective properties of various gases and gas mixtures were studied in hyperbaric kidney preservation by freezing to ––32 °C at 5–7 atü. After a 12-day storage period the canine kidneys were connected to the neck vessels of the donor and function assessed by measuring urinary output, urea clearance and creatinine clearance after recirculation. In addition, microscopic examination was performed. Using various hyperbaric gases clear differences in function and renal structure were obtained. Xenon pure and xenon/carbogen mixtures demonstrated the best

ISSN:0042-1138    

DOI:10.1159/000279841

出版商:S. Karger AG    

年代:1973

数据来源: Karger

摘要:

The regulation of body water during hypotonic expansion (0.6% NaCl; 0.32 ml/kg/min i.v.) of the extracellular space was investigated in 16 male rabbits with different creatinine clearances due to variations in salt intake. In group A (n = 6) sodium intake was 43 mEq/kg/day, in group B (n = 10) 0.6 mEq/kg/day. After 2 weeks the exogenous creatinine clearance in group A averaged 3.85 ± SD 0.62 ml/min/kg, in group B 2.52 ± SD 0.58 ml/min/kg (p 0.60), but by a different tubular reabsorption of sodium: group A: 95.1 ± SD 2.11%, group B: 89.4 ± SD 1.53% (p < 0.001). Our results suggest that a physiological mechanism controls the decreased tubular reabsorption of sodium in kidneys with reduced glomerular filtration rates during a rapid hypotonic expansion of the extracellu

ISSN:0042-1138    

DOI:10.1159/000279842

出版商:S. Karger AG    

年代:1973

数据来源: Karger

摘要:

The hematogenous and the ascending routes of infection are mainly discussed in the pathogenesis of pyelonephritis (PN). Animal experiments were initiated to study the efficiency of either route and the influence of additional factors, such as virulence of the infecting organisms, application of hormones, or mechanical lesion on the kidney. The ascending route of infection was not effective without additional facilitating factors, except for the E. coli O2 strain; due to application of hormones (estrogen, progesterone, prednisolone) PN occurred with serum resistant strains in a significant number of kidneys, but not with serum-sensitive strains. Medication of hormones or microtrauma (endovesical instillation of 1 ml of sterile saline) alone did not render the hematogenous route of infection effective, whereas the combination of both hormone and microtrauma resulted in a high incidence of renal infection. Ligature of the ureter made the kidneys equally susceptible to infection by both routes, irrespective of the virulence of the E. coli strain. It is concluded that in the pathogenesis of PN both the hematogenous and the ascending routes of infection are possible. The E. coli organisms will take the one pathway or the other depending on the infection facilitating factors that prevail in the individual case.

ISSN:0042-1138    

DOI:10.1159/000279843

出版商:S. Karger AG    

年代:1973

数据来源: Karger

摘要:

Serum and urine of hypernephroid carcinoma patients were studied by immunological, electrophoretic and gel chromatographical methods. 9 of 12 tumor urines contain up to four antigens, which could not be neutralized by normal urine and, with one exception, by normal serum. The antigens seem to be of protein nature, in agar gel electrophoresis they show up in the α2-γ-globulin range, their molecular weight is below the exclusion point of Sephadex-G 15

ISSN:0042-1138    

DOI:10.1159/000279844

出版商:S. Karger AG    

年代:1973

数据来源: Karger

摘要:

Complete unilateral ligation of the ureter causes a functional increase in the contralateral kidney by 32% as measured by the split 131J-hippuranclearance test. These values seem to be lower than those obtained after unilateral nephrectomy. Controls before and after uninephrectomy in 27 patients showed an increase of hippuran clearance by 25% not only in healthy organs but also in preoperatively damaged kidneys. Greatest functional increase was seen after removal of a pyonephrotic kidney

ISSN:0042-1138    

DOI:10.1159/000279845

出版商:S. Karger AG    

年代:1973

数据来源: Karger