| 1. |
The Situation of the Haemophiliac Yesterday and Today |
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Pathophysiology of Haemostasis and Thrombosis,
Volume 10,
Issue 1,
1981,
Page 1-11
H. Egli,
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ISSN:1424-8832
DOI:10.1159/000214421
出版商:S. Karger AG
年代:1981
数据来源: Karger
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| 2. |
The Effects of Albumin-Bound Unsaturated Fatty Acids on Platelets |
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Pathophysiology of Haemostasis and Thrombosis,
Volume 10,
Issue 1,
1981,
Page 3-13
Nina Refsum,
Carol Lowery,
Arne Nordøy,
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摘要:
Unsaturated fatty acids (FA) were bound to human albumin in a molar ratio of 2 and were then added to platelet-rich plasma (PRP), increasing the total FA concentration by 1 mM. Separate FA and FA paired with di-homo-γ-linolenic acid (DHLA) and arachidon-ic acid (AA), respectively, were incubated with PRP for 5 and 90 min, and platelet aggregation and platelet factor 3 (PF3) activity were measured. DHLA inhibited adenosine-diphos-phate- and collagen-induced platelet aggregation after 5 min, an effect which was enhanced after 90 min. The effects of AA, which stimulated platelet aggregation and increased PF3 activity, were partially counteracted by DHLA after 90 min. When linoleic acid and AA were incubated with PRP in equimolar concentrations for 90 min, an inhibition of collagen-induced platelet aggregation was observed which was not observed after incubation with these FA separately. This study indicates that exogenous albumin-bound AA and DHLA may be used directly by the platelet cyclo-oxygenase pathway before significant incorporation into the platelet phosphoüpids has occurre
ISSN:1424-8832
DOI:10.1159/000214382
出版商:S. Karger AG
年代:1981
数据来源: Karger
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| 3. |
Introduction to Conference Workshop Sessions and International Status Reports |
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Pathophysiology of Haemostasis and Thrombosis,
Volume 10,
Issue 1,
1981,
Page 12-13
Martin J. Inwood,
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ISSN:1424-8832
DOI:10.1159/000214425
出版商:S. Karger AG
年代:1981
数据来源: Karger
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| 4. |
Workshop Programme |
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Pathophysiology of Haemostasis and Thrombosis,
Volume 10,
Issue 1,
1981,
Page 14-15
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ISSN:1424-8832
DOI:10.1159/000214426
出版商:S. Karger AG
年代:1981
数据来源: Karger
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| 5. |
Workshop Participants |
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Pathophysiology of Haemostasis and Thrombosis,
Volume 10,
Issue 1,
1981,
Page 16-17
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PDF (371KB)
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ISSN:1424-8832
DOI:10.1159/000214427
出版商:S. Karger AG
年代:1981
数据来源: Karger
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| 6. |
Workshop Reports |
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Pathophysiology of Haemostasis and Thrombosis,
Volume 10,
Issue 1,
1981,
Page 18-18
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ISSN:1424-8832
DOI:10.1159/000214428
出版商:S. Karger AG
年代:1981
数据来源: Karger
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| 7. |
Introduction: Questions Regarding Comprehensive Care -A Haemophiliac Concerns |
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Pathophysiology of Haemostasis and Thrombosis,
Volume 10,
Issue 1,
1981,
Page 19-22
Donald E. Colburn,
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ISSN:1424-8832
DOI:10.1159/000214429
出版商:S. Karger AG
年代:1981
数据来源: Karger
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| 8. |
The Haematologic/Orthopedic/Physiatric Team Effort |
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Pathophysiology of Haemostasis and Thrombosis,
Volume 10,
Issue 1,
1981,
Page 23-25
H.H. Brackmann,
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ISSN:1424-8832
DOI:10.1159/000214460
出版商:S. Karger AG
年代:1981
数据来源: Karger
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| 9. |
The Role of the Nurse Coordinator |
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Pathophysiology of Haemostasis and Thrombosis,
Volume 10,
Issue 1,
1981,
Page 26-29
T. Holbrook,
C.C. Mintzer,
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ISSN:1424-8832
DOI:10.1159/000214461
出版商:S. Karger AG
年代:1981
数据来源: Karger
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| 10. |
Study of Platelet Diameter Distribution in Patients with Valvular Heart Disease and with Prosthetic Heart Valve Replacement |
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Pathophysiology of Haemostasis and Thrombosis,
Volume 10,
Issue 1,
1981,
Page 28-36
M. Dumoulin,
M. Tirmarche,
M.H. Horellou,
J. Acar,
M. Samama,
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摘要:
We have studied the platelet count and the megathrombocyte index (MI), or percentage of platelets that have a diameter greater than 2.9 μm, in 100 patients with valvular heart disease. The mean platelet count is significantly lower than in controls (p < 0.0005) and the MI is significantly increased (p < 0.01). No difference was observed in these two parameters according to the variety of the valvular heart disease. 45 of the same patients were studied after prosthetic heart valve replacement. Our results show a significant elevation of platelet count and a significant decrease of MI compared with the presurgical values in all groups except in the mitral one in which MI remains increased. This work demonstrates the presence of platelet abnormalities which reveal a compensated thrombo-cytolytic state in patients with valvular heart disease and its partial correction after aortic, but not mitral, valve replacement
ISSN:1424-8832
DOI:10.1159/000214384
出版商:S. Karger AG
年代:1981
数据来源: Karger
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