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1. |
Prevention of Preterm BirthNew Initiatives Based on Microbial‐Host Interactions |
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Obstetrical & Gynecological Survey,
Volume 43,
Issue 1,
1988,
Page 1-14
JAMES MCGREGOR,
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摘要:
&NA;Preterm delivery remains a preeminent problem in reproductive and pediatric care worldwide. Recent data suggest that cervicovaginal microflora and/or the inflammatory response they engender produce factors which can cause or predispose to preterm labor and rupture of membranes. Microorganisms mediating such processes may not be “recognized pathogens” and are often considered normal flora. These microorganisms may act singly, additively, or synergistically with host factors released during an induced inflammatory response. Quantitative, as well as qualitative aspects of cervicovaginal microflora may be important. Multiple cervicovaginal microorganisms produce IgA protease, neuraminidase, and mucinase which may facilitate passage of these and other agents past cervical barriers and into the lower uterine segment. Multiple microflora also produce phospholipases A2and C, each of which can locally augment production of eicosanoids within the uterus which are important in cervical ripening and labor. Similar microflora produce various proteases, including collagenase, which can focally weaken the amniochorion and predispose to premature rupture of membranes and cervical ripening. Intrauterine microorganisms induce inflammatory reaction and may engender local release of similar proteases, phospholipases, as well as platelet‐activating factor (PAF) and lymphokines which can also initiate or further potentiate labor‐inducing mechanisms. Recognition of microbe‐induced pathogenesis of some cases of preterm birth offers the hope of specific treatment and prophylaxis. In recent studies, administration of erythromycin and tocolytic agents was associated with an improved outcome in selected women with preterm labor. Further microbiological and clinical studies are ongoing. “Just why so many gravidas go into labor prematurely and hence give birth to infants who often are unable to cope with extrauterine conditions is one of the great unsolved problems of obstetrics.”(1).
ISSN:0029-7828
出版商:OVID
年代:1988
数据来源: OVID
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2. |
Development of Cervical and Vaginal Squamous Cell Neoplasia As a Late Consequence ofIn UteroExposure to Diethylstilbestrol |
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Obstetrical & Gynecological Survey,
Volume 43,
Issue 1,
1988,
Page 15-21
JACOB BORNSTEIN,
ERVIN ADAM,
KAREN ADLER‐STORTHZ,
RAYMOND KAUFMAN,
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摘要:
&NA;During the last 14 years, several articles have given contradictory reports on prevalence rates of squamous cell neoplasia of the cervix and vagina in diethylstilbestrol (DES)‐exposed progeny. In 1984, the DES‐Adenosis (DESAD) Project found that the incidence of cervical and vaginal intraepithelial neoplasia in DES‐exposed daughters was twice as high as in a comparison group of unexposed women. This was also associated with a higher rate of herpes simplex virus and human papillomavirus infections. Possible hypotheses on the etiology of the increased incidence of squamous neoplasia are discussed.
ISSN:0029-7828
出版商:OVID
年代:1988
数据来源: OVID
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3. |
A Proposed Mechanism for Premature Rupture of Membranes |
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Obstetrical & Gynecological Survey,
Volume 43,
Issue 1,
1988,
Page 22-28
NEAL LONKY,
ROBERT HAYASHI,
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ISSN:0029-7828
出版商:OVID
年代:1988
数据来源: OVID
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4. |
Precision and Accuracy of Doppler Flow MeasurementsIn VitroandIn VivoStudy of the Applicability of the Method in Human Fetuses |
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Obstetrical & Gynecological Survey,
Volume 43,
Issue 1,
1988,
Page 29-31
KNUD RASMUSSEN,
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ISSN:0029-7828
出版商:OVID
年代:1988
数据来源: OVID
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5. |
Effect of Gestational Age on Fetal and Intervillous Blood Gas and Acid‐Base Values in Human Pregnancy |
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Obstetrical & Gynecological Survey,
Volume 43,
Issue 1,
1988,
Page 32-35
PETER SOOTHILL,
KYPROS NICOLAIDES,
CHARLES RODECK,
STUART CAMPBELL,
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ISSN:0029-7828
出版商:OVID
年代:1988
数据来源: OVID
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6. |
Fetal Death following Antepartum Fetal Heart Rate TestingA Review of 65 Cases |
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Obstetrical & Gynecological Survey,
Volume 43,
Issue 1,
1988,
Page 35-37
CARL SMITH,
HOA NGUYEN,
BRUCE KOVACS,
DOROTHY MCCART,
JEFFERY PHELAN,
RICHARD PAUL,
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ISSN:0029-7828
出版商:OVID
年代:1988
数据来源: OVID
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7. |
Reporting Obstetric Ultrasound |
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Obstetrical & Gynecological Survey,
Volume 43,
Issue 1,
1988,
Page 37-38
MARGARET FURNESS,
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ISSN:0029-7828
出版商:OVID
年代:1988
数据来源: OVID
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8. |
Rubella Susceptibility and the Continuing Risk of Infection in Pregnancy |
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Obstetrical & Gynecological Survey,
Volume 43,
Issue 1,
1988,
Page 38-39
CHRISTINE MILLER,
ELIZABETH MILLER,
PAULINE WAIGHT,
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ISSN:0029-7828
出版商:OVID
年代:1988
数据来源: OVID
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9. |
Streptococcus milleriand Second Trimester Abortion |
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Obstetrical & Gynecological Survey,
Volume 43,
Issue 1,
1988,
Page 40-41
A. MACGOWAN,
P. TERRY,
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ISSN:0029-7828
出版商:OVID
年代:1988
数据来源: OVID
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10. |
Court‐Ordered Obstetrical Interventions |
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Obstetrical & Gynecological Survey,
Volume 43,
Issue 1,
1988,
Page 41-43
VERONIKA KOLDER,
JANET GALLAGHER,
MICHAEL PARSONS,
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PDF (2160KB)
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ISSN:0029-7828
出版商:OVID
年代:1988
数据来源: OVID
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