摘要:

The distribution of immunoglobulin (Ig)- containing cells in the gastric antral mucosa of patients with various abnormalities of the stomach was studied by fluorescent antibody techniques. IgA-containing cells comprised about 80% of all Ig-containing cells and were diffusely distributed in the interstitial spaces of gastric glands. IgA was observed in the apical portion of the cytoplasm of cells in some pyloric glands, and IgM was seen extracellularly between the epithelial cells and in the lumen. At the base of gastric cancers, adjacent to the invading cancer mass, IgG-containing immunocytes were found in intermuscular spaces, and some cells that appeared to be cancer cells reacted with anti-IgG or anti-IgM.

ISSN:0012-2823    

DOI:10.1159/000197537

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

Immunoglobulins (Igs) in gall bladder bile were measured by radial immunodiffusion, and the distribution of Ig-containing cells in gall bladder mucosa was studied by immunofluorescence. Ig-containing cells were considerably less numerous than in the alimentary tract, although as in gastrointestinal mucosa, IgA-containing cells greatly exceeded IgM- and IgGcontaining cells. The total number of immunocytes in gall bladder mucosa was not correlated with severity of cholecystitis, except for moderately increased numbers of IgM -containing cells in empyematous gall bladders. There were, however, increased numbers of IgG- and IgM-containing cells in muscle layers of severely inflamed gall bladders. Ig levels in bile were highly variable and often bore no quantitative relationship to the number of gall bladder immunocytes. This may indicate that biliary Ig concentrations are influenced by multiple factors, such as variable contributions from the liver, transudation or absorption across inflamed mucosa, or local synthesis and secretion by the gall bladder.

ISSN:0012-2823    

DOI:10.1159/000197538

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

A comparison has been made of the pattern of pancreatic enzyme activities in the duodenal juice of 32 healthy subjects, upon intravenous injection of GIH secretin (1 clinical unit/kg body weight), Farmitalia caerulein (40 ng/kg), or GIH cholecystokinin (1 Ivy dog u/kg), given alone or combined (according to 3 submaximum rapid injection schedules). Enzymatic activities were measured in 5- to 10-min duodenal aspirates. A close correlation between trypsin and chymotrypsin activities was evident under all circumstances. On the other hand there was an apparent delay in amylase and lipase responses after the bolus administration of caerulein or cholecystokinin.

ISSN:0012-2823    

DOI:10.1159/000197539

出版商:S. Karger AG    

年代:1974

数据来源: Karger

ISSN:0012-2823    

DOI:10.1159/000188180

出版商:S. Karger AG    

年代:1904

数据来源: Karger

ISSN:0012-2823    

DOI:10.1159/000188181

出版商:S. Karger AG    

年代:1904

数据来源: Karger

摘要:

The antibody titres against E. coli 0:14 were examined with an haemagglutination method in the serum of patients with ulcerative colitis and of those suffering from other diseases. No significant difference was observed between the groups of patients. These results, which contradict previously published data, do not support the view that E. coli plays an important role in the pathogenesis of ulcerative colitis.

ISSN:0012-2823    

DOI:10.1159/000197540

出版商:S. Karger AG    

年代:1974

数据来源: Karger

ISSN:0012-2823    

DOI:10.1159/000197541

出版商:S. Karger AG    

年代:1974

数据来源: Karger

ISSN:0012-2823    

DOI:10.1159/000188182

出版商:S. Karger AG    

年代:1904

数据来源: Karger

ISSN:0012-2823    

DOI:10.1159/000188183

出版商:S. Karger AG    

年代:1904

数据来源: Karger

ISSN:0012-2823    

DOI:10.1159/000197542

出版商:S. Karger AG    

年代:1974

数据来源: Karger