摘要:

The infrared absorption spectrum of sedamine, an alkaloid occurring inSedumacreL., is exactly superposable on that of synthetic 1-methyl-2-(β-hydroxy-β-phenylethyl)-piperidine. The melting points of the bases and their hydrochlorides, alone and in admixture, indicate that sedamine is probably one of the optically active forms of the synthetic diastereomer.

ISSN:0008-4042    

DOI:10.1139/v51-040

出版商:NRC Research Press    

年代:1951

数据来源: NRC

摘要:

Jaborandine, the active principle ofPiperjaborandiVelloso, has been shown to be an ester ofp-aminobenzoic acid and an amino alcohol which contains a tertiary nitrogen with an N–CH3group and has the formula C11H23ON.

ISSN:0008-4042    

DOI:10.1139/v51-041

出版商:NRC Research Press    

年代:1951

数据来源: NRC

摘要:

Two new dehydrolupanines, C15H22N2O, have been prepared: (1) by the mercuric acetate dehydrogenation of the alkaloidd-lupanine, and (2) by the N-bromosuccinimide dehydrogenation ofd-lupanine. The conversion ofd-lupanine to its diastereoisonieric alkaloidd-α-isolupanine has been effected by mercuric acetate dehydrogenation followed by catalytic hydrogenation. On the basis of evidence and knowledge at present accumulated it has been possible to assign absolute stereochemical structures to a number of C15lupin alkaloids.

ISSN:0008-4042    

DOI:10.1139/v51-042

出版商:NRC Research Press    

年代:1951

数据来源: NRC

摘要:

The iminodiacetic acids have been examined as possible complexing agents in the chromatographic separation of the rare earths with cation exchange resins. The ammonium salts of these acids form complex ions involving both one and two iminodiacetate ions of increasing stability with the rare earth elements of greater atomic number. Methods greatly reducing the time and material requirements are presented for the separation of the cerium group elements with nitrilotriacetic acid.

ISSN:0008-4042    

DOI:10.1139/v51-043

出版商:NRC Research Press    

年代:1951

数据来源: NRC

摘要:

The activation energies for the exchange reactions between sodium iodide and cyclopentyl, cycloheptyl, cycloöctyl, cyclopentadecyl, and 2-heptyl iodides were all in the range 21 ± 1 kcal. per mole. For cyclohexyl iodide the value was 25.6 kcal. per mole. This difference seems to be explained from a consideration of the initial potential energies of the various rings. An inverse relation appears to exist between logPZand, the reciprocal of the number of carbon atoms in the iodides investigated, for all the iodides except cyclopentyl iodide. This might be due to a change in the number of equivalent constellations in the activated state.

ISSN:0008-4042    

DOI:10.1139/v51-044

出版商:NRC Research Press    

年代:1951

数据来源: NRC

摘要:

This reaction at 35°C. exhibits a behavior indicative of the presence of an intermediate in the reaction. Reaction of paraformaldehyde and ammonium nitrate in glacial acetic acid resulted in the isolation of hexamine dinitrate. Evidence is presented to indicate that formation of hexamine dinitrate, accompanied by the production of nitric acid, is responsible for the production of RDX in the acetic anhydride system.

ISSN:0008-4042    

DOI:10.1139/v51-045

出版商:NRC Research Press    

年代:1951

数据来源: NRC

摘要:

A series of 1-substituted-2-nitramino-2-imidazolines have been prepared and nitrated in mixed-acid and nitric acid – acetic anhydride media. These compounds gave the corresponding 1-substituted-2-nitrimino-3-nitroimidazolidines which proved to be quite stable. The hydrolysis products of some of these compounds are described.

ISSN:0008-4042    

DOI:10.1139/v51-046

出版商:NRC Research Press    

年代:1951

数据来源: NRC

摘要:

Several new substituted nitroguanidines were prepared by the reaction of amines with N-methyl-N-nitroso-N′-nitroguanidine. N-γ-Nitroxybutyl-N′-nitroguanidine was cyclized to 1-nitro-2-amino-6-methyl-Δ2-tetrahydropyrimidinium nitrate by refluxing in water.

ISSN:0008-4042    

DOI:10.1139/v51-047

出版商:NRC Research Press    

年代:1951

数据来源: NRC

摘要:

Certain dehydration and oxidation products of cholesterol were prepared for subsequent animal experimentation. The ultraviolet absorption spectra of those derivatives possessing two or more conjugate chromophores were determined spectrophotometrically over the wave length range of 220 mμ to 350 mμ. The relative coincidence of the experimental λmaxand ϵmaxvalues of cholestadiene-3, 5 and of the enol acetate of cholesten–4–one–3 is offered as support for a 3, 5-diene structure for the latter steroid in particular and for enol esters of 4,5-unsaturated 3-ketosteroids in general.

ISSN:0008-4042    

DOI:10.1139/v51-048

出版商:NRC Research Press    

年代:1951

数据来源: NRC

摘要:

The needlelike crystals which form in aerated submerged cultures of the corn smutUstilago zeae(PRL-119) were found to be aD-glucolipid, m.p. 146-7°C,(pyridine), which contained one carboxyl group, two ester groups, at least two terminal methyl groups, and twoD-glucose residues per mole. On the basis of elementary analyses, neutralization equivalent, and molecular weight estimations, the molecular formula of the material isolated was approximately C37H62−6O17. The substance was not shown to be chemically homogeneous. Conditions used in culturing the fungus in stirred fermentors to produce the crystalline metabolic product, which was termed "ustilagic acid", are described, and a procedure for the isolation of the material is given.

ISSN:0008-4042    

DOI:10.1139/v51-049

出版商:NRC Research Press    

年代:1951

数据来源: NRC