摘要:

The hydrogenolysis and hydrolysis of α-cyanobromolycopodine to the secondary tricyclic base, α-des-dihydrolycopodine, is reported. The latter compound was converted to the methiodide in poor yield so that further degradations of the molecule through this derivative were not feasible. Hydride reductions of α-cyanobromolycopodine and some of its derivatives are recorded. The presence of a methylene group adjacent to the carbonyl group in lycopodine has been proved. Evidence is presented which suggests that the carbonyl group and the nitrogen atom are relatively close to one another in the molecule.

ISSN:0008-4042    

DOI:10.1139/v56-198

出版商:NRC Research Press    

年代:1956

数据来源: NRC

摘要:

Further evidence for the α-configuration of the hydroxyl groups in hyocholic acid is presented and several related compounds are described.

ISSN:0008-4042    

DOI:10.1139/v56-199

出版商:NRC Research Press    

年代:1956

数据来源: NRC

摘要:

Representative members of the series of ω-fluoroalkyl methanesulphonates,p-toluenesulphonates, acetates, and benzoates have been prepared, and some of their chemical, physical, and toxicological properties determined.

ISSN:0008-4042    

DOI:10.1139/v56-200

出版商:NRC Research Press    

年代:1956

数据来源: NRC

摘要:

The application of light absorption data to determine minimum interference radii of various atoms in solution is examined. Three separate methods are suggested and the relation between potential energy and interatomic distance of two non-bonded atoms is discussed. The values obtained in neutral solution are as follows: H, 0.95 ± 0.1 Å; O (in C=O), 1.0 ± 0.15 Å; and CH3, 1.7 ± 0.2 Å.

ISSN:0008-4042    

DOI:10.1139/v56-201

出版商:NRC Research Press    

年代:1956

数据来源: NRC

摘要:

The surface enthalpy of NaCl has been redetermined from heats of solution of salt samples of different specific surface areas. Special care was taken in the preparation of these samples to avoid contamination by nitrate and excess sodium. The value obtained, 276 ergs/cm.2, differs from that reported by Benson and Benson, viz. 305 ergs/cm.2, for samples containing some nitrate impurity.

ISSN:0008-4042    

DOI:10.1139/v56-202

出版商:NRC Research Press    

年代:1956

数据来源: NRC

摘要:

Basic derivatives of 6-chloroquinazoline and phthalazine have been synthesized and screened for their physiological action on the central nervous system. Sodium dialkylaminoalkoxides and the appropriate chlorobenzodiazine were brought together to yield basic ethers of 6-chloroquinazoline and phthalazine respectively. 1-(γ-Dimethylaminopropylamino)phthalazine was also prepared.

ISSN:0008-4042    

DOI:10.1139/v56-203

出版商:NRC Research Press    

年代:1956

数据来源: NRC

摘要:

Acetosyringone has been synthesized from acetovanillone, in better than a 50% yield, through conversion to 5-iodoacetovanillone followed by its interaction with sodium methoxide in the presence of copper catalyst. The previously unreported intermediate, 5-iodoacetovanillone, was characterized by methylation to 5-iodoacetoveratrone and subsequent oxidation to the known 5-iodoveratric acid.

ISSN:0008-4042    

DOI:10.1139/v56-204

出版商:NRC Research Press    

年代:1956

数据来源: NRC

摘要:

A series of 1-(β-dialkylaminoethyl)-2-imidazolidinethiones and their picrates are described. 1-(β-Diethylaminoethyl)-2-methylmercapto-2-imidazoline dihydroiodide combined with benzylamine with the evolution of methyl mercaptan to give 1-(β-diethylaminoethyl)-2-benzylamino-2-imidazoline (III). In a similar reaction β-alanine gave a product whose picrate gave analytical values in agreement with those calculated for the dipicrate of 1-(β-diethylaminoethyl)-5-keto-Δ8-hexahydro-1,4,8-pyrimidazole (IV).

ISSN:0008-4042    

DOI:10.1139/v56-205

出版商:NRC Research Press    

年代:1956

数据来源: NRC

摘要:

Graphite ferric chloride, C12FeCl3, was prepared by heating anhydrous ferric chloride with graphite at 305 °C. The purified compound containing 53% ferric chloride was not attacked by hot 6 Nhydrochloric acid and gave an X-ray diffraction pattern which was distinctly different from that of either graphite or ferric chloride. The separation of the graphite layer-planes was increased from 3.36 to 9.4 Å by the intercalation of the ferric chloride molecules.Tests for exchange between C12FeCl3and Fe+++ion were made using radioactive Fe59. In no instance was any measurable exchange observed. The compound was subjected to neutron irradiation and the Szilard–Chalmers yield of separable activity calculated and identified. The separated portion contained less than 1% of the total activity and consisted of Fe59, P32, and S35.The lack of exchange and the low Szilard–Chalmers yield are attributed to the formidable steric hindrance effects which result from the "stacked layer" structure for graphite ferric chloride.

ISSN:0008-4042    

DOI:10.1139/v56-206

出版商:NRC Research Press    

年代:1956

数据来源: NRC

摘要:

Finely divided spruce wood was heated with aqueous sodium bicarbonate and excess carbon dioxide up to 160° and about 400 p.s.i. in attempts to carboxylate the lignin according to the Kolbe–Schmitt method and to extract the product as a soluble sodium salt. Only small amounts of lignin were removed, together with larger amounts of the holocellulose. Heating the wood with anhydrous liquid ammonia up to 100° and about 900 p.s.i. extracted only small amounts of material from the softwood spruce, but 25 to 30% of the lignin was removed from the hard woods beech, birch, and maple and 52% from rye straw. The solution of ammonium chloride or sodium cyanide in the liquid ammonia increased these percentages substantially, and also the concomitant extraction of holocellulose.

ISSN:0008-4042    

DOI:10.1139/v56-207

出版商:NRC Research Press    

年代:1956

数据来源: NRC