摘要:

The temperature dependence of the13C kinetic isotope of the α-carbon in benzyl bromide (1) and in 1-bromo-1-phenylethane (2) has been measured for reaction with alkoxide ion. For these bimolecular displacements, a relatively large temperature effect was found, comparable to that reported for other SN2 processes. A reexamination of the reaction of2with EtO−has shown an earlier value fork12/k13to be in error.

ISSN:0008-4042    

DOI:10.1139/v68-303

出版商:NRC Research Press    

年代:1968

数据来源: NRC

摘要:

The infrared frequencies and apparent half band widths of the O—H stretching band of a series of 2,6-dimethyl-4-substituted phenols and a series of 2,6-dichloro-4-substituted phenols have been measured in carbon tetrachloride solution. The slopes of the Hammett plots for the frequencies and half band widths of both these series are compared with those calculated from published data for 2,6-di-t-butyl-4-substituted phenols and 3- or 4-substituted phenols. Significant differences are found in ρ obtained from the frequency data for the four series. The 2,6-dimethyl-4-substituted phenols, unlike the unhindered phenols, are found to parallel the 2,6-di-t-butyl-4-substituted phenols in having a negative ρ for the frequency data and a negative ρ for the half band width correlation. It is concluded that the negative ρ from the half band widths of 2,6-di-t-butyl-4-substituted phenols is primarily a result of electronic rather than steric factors.

ISSN:0008-4042    

DOI:10.1139/v68-304

出版商:NRC Research Press    

年代:1968

数据来源: NRC

摘要:

not available

ISSN:0008-4042    

DOI:10.1139/v68-305

出版商:NRC Research Press    

年代:1968

数据来源: NRC

摘要:

Nine new β,β-diarylhydracrylic acids are reported from the condensation of monosubstituted benzophenones with ethyl bromoacetate in Reformatsky reactions. The reaction of 4-nitrobenzophenone which fails to go into classical Reformatsky reactions can be accomplished in excellent yield by the two-step process; however, 2-nitrobenzophenone fails to react under any conditions.In the case of 2-chlorobenzophenone in benzene–toluene, the hydracrylic acid is not isolated, but rather the unsaturated β-chlorophenyl-β-phenyacrylic acid. Diethyl ether appeared in general to be superior to benzene–toluene as a solvent for the reactions. Anisole under reduced pressure has also been used successfully in two cases.

ISSN:0008-4042    

DOI:10.1139/v68-306

出版商:NRC Research Press    

年代:1968

数据来源: NRC

摘要:

not available

ISSN:0008-4042    

DOI:10.1139/v68-307

出版商:NRC Research Press    

年代:1968

数据来源: NRC

摘要:

Certain 1,2-dithiolium salts react with primary amines in alcoholic solution to provide 1-aminopropene-3-thiones, which can be oxidized by iodine to form isothiazolium salts. These react with sulfur in pyridine to form isothiazole-3-thiones, which react with methyl iodide to form 3-methylthioisothiazolium iodides.

ISSN:0008-4042    

DOI:10.1139/v68-308

出版商:NRC Research Press    

年代:1968

数据来源: NRC

摘要:

A series of 107 1,4-naphthoquinones and related products has been synthesized to study their mode of action in bacterial growth inhibition. Theinvitroreactions of a number of these with aniline,n-butylamine, sodium methoxide, and ann-buthanethiol–triethylamine mixture have been examined. A series of epoxides of C-2 monosubstituted and C-2,C-3 disubstituted 1,4-naphthoquinones has been synthesized and their reactions with amines, thiols, and halogen acids have been studied. The ultraviolet absorption maxima of many of these quinones are also tabulated.

ISSN:0008-4042    

DOI:10.1139/v68-309

出版商:NRC Research Press    

年代:1968

数据来源: NRC

摘要:

Twelve new substituted thiosemicarbazones have been prepared from formylferrocene and 2- and 4-monosubstituted and 4,4-disubstituted thiosemicarbazides. The infrared spectra of these compounds are discussed in some detail. Copper complexes of three of them were synthesized and their structures established. They were found to be strongly paramagnetic. The electronic absorption spectra of the thiosemicarbazones and the copper complexes are reported.

ISSN:0008-4042    

DOI:10.1139/v68-310

出版商:NRC Research Press    

年代:1968

数据来源: NRC

摘要:

The configurations and conformations ofS-methyl benzothiohydroxamic acid (3) and itsS-oxo andS,S-dioxo derivatives (5) and (7) were established by means of a graphical comparison of their dipole moments with those of the correspondingp-nitro compounds.The proton magnetic resonance and infrared spectra of these compounds were also studied.It is concluded that the relative stability of stereoisomers in the series of compounds C6H5C(NOH)X seems to depend more on the electronic nature of the group X than on its steric requirements.

ISSN:0008-4042    

DOI:10.1139/v68-311

出版商:NRC Research Press    

年代:1968

数据来源: NRC

摘要:

The alkaloid ofSamaneasamanMerr. Pithecolobine is shown to be a family of closely related analogues of the general formula (13). The structure (9a) has been proved for one of these compounds.

ISSN:0008-4042    

DOI:10.1139/v68-312

出版商:NRC Research Press    

年代:1968

数据来源: NRC