摘要:

The purpose of this investigation was to evaluatethe effect of non‐surgical periodontal treatment and adjunctive systemic minocycline therapy on the level of neutral protease activity in whole saliva of adults with periodontitis. A test group of 21 adult patients with moderate to severe periodontitis was compared to a control group of 5 adults with healthy periodontium. Four test groups were examined: 1) scaling and root planing (SRP), probing depth = 4 to 5 mm; 2) SRP, PD ≥ 6 mm; 3) SRP and adjunctive systemic minocycline therapy, PD = 4 to 5 mm; and 4) SRP and adjunctive systemic minocycline therapy, PD ≥ 6 mm. Clinical parameters and levels of neutral protease in whole saliva were assessed at baseline and on the sixth week after the non‐surgical periodontal treatment. Neutral protease activity was measured by spectrofluorimetric method. Statistical tests of Mann‐Whitney and Spearman Rank correlation coefficient were used in the evaluation of the mean values of measurements. The mean values of protease activity were significantly higher in the test groups than in the control group at baseline. Six weeks after non‐surgical therapy, patients with 4 to 5 mm probing depth had approximate values of protease activity comparable to the control group. Hence it can be argued that these patients did not need minocycline HCL as an adjunctive therapy. However, non‐surgical therapy had limited effects on both clinical parameters and enzyme activities for subjects with ≥ 6 mm probing depth; on the other hand, gingival inflammation and enzyme activities were reduced significantly by the usage of minocycline as adjunctive therapy in these patients. According to our results, neutral protease activity in saliva is related to probing depth and gingival bleeding index, and not related to age and epithelial cell number. For these reasons, systemic minocycline therapy might be useful as an adjunct to non‐surgical therapy in the presence of deep pockets, especially for reinfected cases. Further investigations are needed to confirm this suggestion.J Periodontol 1996;67:1–6.

ISSN:1049-8885    

DOI:10.1902/jop.1996.67.1.1

出版商:Wiley    

年代:1996

数据来源: WILEY

摘要:

Twelve patients with bilateral comparablegingival recessions were treated using a split mouth design, to compare the relative success of root coverage by two regenerative procedures. The areas of recession treated were Class I or II according to Miller's classification and caused either an esthetic problem and/or root sensitivity. The symmetrical defects, on the maxillary canines, 4 mm or deeper, were randomly assigned in each patient to surgical procedures with either a bioresorbable matrix barrier (test) or a non‐resorbable expanded polytetrafluoroethylene membrane (control). Gingival recession, clinical attachment level, probing depth, and extension of keratinized tissue were measured at baseline and at 6 months postsurgically. Both procedures resulted in significant root coverage (P<0.0001) and attachment gain (P<0.0001). The gingival recession decreased from 4.75 ± 0.22 mm to 0.83 ± 0.24 mm and from 4.75 ± 0.22 mm to 0.75 ± 0.22 mm, corresponding to a mean root coverage of 82.4% and 83.2%, at the test and control sites respectively. The average clinical attachment gain was 4.33 ± 0.44 mm at the test sites compared to 4.42 ± 0.48 mm for the non‐resorbable barrier. No significant changes were found for probing depth and keratinized tissue. Data analysis did not demonstrate any significant difference between the two procedures for any of the variables included. However, a questionnaire given to each patient revealed the single‐step surgery to be the patients' choice.J Periodontol 1996;67:7–14.

ISSN:1049-8885    

DOI:10.1902/jop.1996.67.1.7

出版商:Wiley    

年代:1996

数据来源: WILEY

摘要:

This communication reports5casesof cervical and 1 apical cemental tears. The diagnosis of the cervical tears was made by a characteristic feature which presented radiographically as a prickle‐like body. The fragment of cementum could be detached by root planing or during periodontal surgery and uneventful healing was obtained following these procedures. The process of aging in addition to continuous occlusal strain may lead to this phenomenon. Cervical cemental tear may be one of the contributing factors in the progress of adult periodontitis.J Periodontol 1996;67:15–20.

ISSN:1049-8885    

DOI:10.1902/jop.1996.67.1.15

出版商:Wiley    

年代:1996

数据来源: WILEY

摘要:

The overgrowth‐affected gingivaof patients treated with cyclosporin A after kidney transplant was examined with ultrastructural and histochemical methods to evaluate the involvement of connective tissue. Gingival overgrowth has the same clinical signs as local edema. The ultrastructural study showed that the dimensional increase was largely due to increased production of amorphous ground substance by fibroblasts, possibly resulting from an increased release of histamine by mast cells. The histochemical data revealed that the affected tissues contained higher levels of glycosaminoglycans and that cyclosporin A induced comparably high levels of glycosaminoglycans in in vitro cultures of fibroblasts obtained from normal gingiva. The combination of ultrastructural and histochemical data, therefore, strongly suggests that the response of the connective tissue in gingival overgrowth cannot be ignored and may be the main cause of the observed pathological condition.J Periodontol 1996;67:21–27.

ISSN:1049-8885    

DOI:10.1902/jop.1996.67.1.21

出版商:Wiley    

年代:1996

数据来源: WILEY

摘要:

There is concern with decreasedair quality and potential aerosol contamination in the dental operatory. This problem has been addressed by the Centers for Disease Control and Prevention, which recommends that all sources of blood‐contaminated splatter and aerosols be minimized. One of the major sources of potential aerosol contamination in the dental setting is the ultrasonic sealer. This study looks at the use of a high volume evacuator attachment for the ultrasonic sealer handpiece. Artificial teeth were mock‐scaled for 1 minute with and without the evacuator attachment. The mock scaling was performed within a plastic enclosure that had a 1 cm grid laid out on 4 sides. Scaling was performed 10 times each by 2 operators. An erythrosin solution was used for the ultrasonic sealer coolant with a coolant volume of 17.5 ml/min. The number of squares containing a red erythrosin spot were counted and considered to represent aerosol contamination. The high volume evacuator attachment produced a 93% reduction in the number of contaminated squares (chi squared significant atP<0.05). There was no increase in heat transfer to a tooth analogue when the high volume evacuator attachment was used with the ultrasonic sealer as compared to the sealer without the evacuator attachment. It is felt that the high volume evacuator attachment is capable of significantly reducing the amount of aerosol contamination produced within the test system without increased heat transfer to the tooth.J Periodontol 1996;67:28–32.

ISSN:1049-8885    

DOI:10.1902/jop.1996.67.1.28

出版商:Wiley    

年代:1996

数据来源: WILEY

摘要:

This study was performedto determine the type of periodontal pathology found in a group of HIV+ patients and its relation to serum levels of CD4. The sample consisted of 101 individuals: intravenous drug users (84%), homosexuals (7%), and heterosexuals (10%). Each patient was examined clinically and radiographically. Periodontal clinical parameters included gingival index and probing depth and loss of attachment on four sites per tooth. Severity of disease was defined as the most severe lesion found: gingivitis, or early, moderate, or advanced periodontitis. CD4 counts were determined on 64 of these patients. Associations between severity of the disease and gender and CD4 counts were analyzed using the Mantel Haenszel chi square test, while associations between severity and age and CD4/CD8 ratio were analyzed using the Kruskal‐Wallis test. No disease was found in 14.8% of the sample, gingivitis was found in 21.8%, early periodontitis in 43.6%, moderate periodontitis in 10.9%, and advanced periodontitis in 8.9%. Linear gingival erythema (LGE) was seen in 17.8% of all patients and necrotizing periodontitis (NUP) in 4.9%. No statistically significant differences were observed between the severity of the disease and CD4 counts.J Periodontol 1996;67:33–36.

ISSN:1049-8885    

DOI:10.1902/jop.1996.67.1.33

出版商:Wiley    

年代:1996

数据来源: WILEY

摘要:

langerhans' cells(LCs)are intraepithelialimmunocompetent cells. Changes in the number of LCs occur in inflammatory and autoimmune diseases. In this study, the number of gingival LCs in patients with type I diabetes mellitus was compared with those of normal individuals using immunohistochemical methods. Gingival biopsies were obtained from 20 type I diabetics and 10 healthy individuals. Anti‐CD1 positive LCs formed an intraepithelial network and showed a marked increase in type I diabetics. This increase was not related to diabetic age. The number of LCs was proportional to the density of subepithelial inflammatory cells. Our findings suggest that LCs may play a role in the development of diabetic gingivitis.J Periodontol 1996;67:37–40.

ISSN:1049-8885    

DOI:10.1902/jop.1996.67.1.37

出版商:Wiley    

年代:1996

数据来源: WILEY

摘要:

This pilot study was undertakento determine the effect of x‐ray beam alignment and spatial resolution on quantification of alveolar bone using radiometric techniques. Six (6) dry mandibles were radiographed at 70 kVp, 10 mA, 0.6 seconds using D‐speed film, with a bone chip (2.64, 4.10, or 6.07 mg) present or absent at 7 x‐ray beam alignments (0°, 2° horizontal, 2° vertical, 4° horizontal, 4° vertical, 6° horizontal, 6° vertical). This resulted in 28 radiographs per mandible. Radiographs were digitized using 50‐ and 200‐μm pixel spatial resolution. Image gray levels were standardized using a simple look‐up table shift. Regions of interest (ROIs) were positioned on the alveolar bone where the bone chips had been placed. Cumulative percent histograms (CPH) were calculated for those ROIs. Regression analysis was used to evaluate the relationships between CPH changes and bone chip size as x‐ray beam angulation and spatial resolution was varied. The resulting R2values for angulation ranges of 0° to 1.4°, 1.5° to 2.4°, and 2.5° to 5.5° were: 0.983, 0.941, 0.891 for 50‐μm pixel images and 0.869, 0.909, and 0.774 for 200‐μm pixel images. We conclude that 50‐μm pixel spatial resolution is apparently superior to 200‐μm pixel images if radiometric data is to be evaluated. With 50‐μm pixel spatial resolution, alignment variations up to 5° may be acceptable in clinical studies, depending on the magnitude of bone change that is to be detected.J Periodontol 1996;67:41–45.

ISSN:1049-8885    

DOI:10.1902/jop.1996.67.1.41

出版商:Wiley    

年代:1996

数据来源: WILEY

摘要:

Adenomatoid odontogenic tumors(AOT)make up3% of odontogenic tumors. This tumor, most commonly found in the maxillary arch, mimics a follicular cyst associated with an impacted tooth. This, is a case report of an AOT found in a 14‐year‐old female undergoing active orthodontic therapy. The surgical removal of the lesion resulted in the exposure of a large bony cavity surrounding the maxillary left canine. Placement of freeze‐dried bone and coverage with an expanded polytetrafluoroethylene membrane resulted in rapid and complete healing of the lesion and restoration of osseous support.J Periodontol 1996;67:46–50.

ISSN:1049-8885    

DOI:10.1902/jop.1996.67.1.46

出版商:Wiley    

年代:1996

数据来源: WILEY

ISSN:1049-8885    

DOI:10.1902/jop.1996.67.1.63

出版商:Wiley    

年代:1996

数据来源: WILEY