摘要:

Aretrospective analysiswas carried out to determine the frequency and onset of endodontic complications occurring in 52 patients treated for advanced periodontal disease. Comparisons were made between teeth which, following periodontal treatment, were used as abutments in fixed prosthetic reconstructions and nonabutment teeth. The study included 672 teeth with initially vital pulps (255 abutment teeth and 417 nonabutment teeth). The observation period varied from 4 to 13 years with a mean of 8.7 years. Pulpal necrosis including periapical lesions developed with a significantly higher frequency in abutment teeth than in nonabutment teeth (15% vs. 3%). The majority of these lesions did not appear until several years following the completion of active treatment. Conceivable reasons for the development of pulpal necrosis in teeth subjected to combined periodontal and prosthetic treatment are discussed.

ISSN:1049-8885    

DOI:10.1902/jop.1984.55.2.63

出版商:Wiley    

年代:1984

数据来源: WILEY

摘要:

Systemic administration of gold saltsfor treatment of arthritis is thought to limit tissue destruction through alteration of inflammatory cell function. The present study ascertained if gold salts could modify the tissue destruction associated with an experimental marginal periodontitis. Therapeutic levels of serum gold salts were established in four squirrel monkeys (experimental) by intramuscular injection of Myochrisine (gold sodium thiomalate 25 mg/ml) at 5 mg/kg/body weight at 4‐day intervals for 12 days. Marginal periodontitis was then induced around mandibular bicuspids by tying plaque retentive ligatures at the gingival margins. Periodontitis was induced around corresponding teeth in four control animals which had not received gold salts. Serum levels of gold salts were maintained in experimental animals, and all animals were killed 2 weeks after induction of periodontitis. Progression of periodontitis was evaluated histometrically on step‐serial sections, and the results analyzed statistically. Specimens from gold‐receiving animals had significantly smaller areas of infiltrated supracrestal connective tissue, and less loss of connective tissue attachment and coronal alveolar bone. Quantitation of total plaque around the ligatures showed no differences; however, there was less plaque located apical to the ligatures in gold‐receiving specimens. Although the study design did not permit identification of the relative importance of cellular or microbial factors, it was concluded that administration of systemic gold salts was associated with significantly less periodontal destruction.

ISSN:1049-8885    

DOI:10.1902/jop.1984.55.2.69

出版商:Wiley    

年代:1984

数据来源: WILEY

摘要:

Aprevious study showedthat the systemic administration of soluble gold salts (gold sodium thiomalate) resulted in significantly less periodontal destruction after 2 weeks of experimentally induced periodontitis. In order to provide information on the possible mechanisms of action of gold salts in the experimental periodontitis situation, the present study analyzed and compared the characteristics of the inflammatory cell populations in animals receiving gold salts with those present in animals which had not received gold salts. Maxillary gingival biopsy specimens were obtained from the buccal aspect of ligatured teeth after 2 weeks of experimental periodontitis. Cell populations were characterized and enumerated, on 1‐micron sections, in an epithelial and superficial connective tissue zone, and a deep connective tissue zone. Significantly fewer inflammatory cells were present in experimental (gold receiving) specimens, and this reduction was due primarily to fewer polymorphonuclear leucocytes (PMNs). No significant reduction occurred in any other inflammatory cell‐type. The reduction in number of PMNs in experimental specimens was associated with a decreased number of morphologically altered, degenerating fibroblasts in the connective tissue compared to the PMN‐dominated lesion of control specimens. Mechanisms whereby gold salts can reduce Chemotaxis and functional capabilities of inflammatory cells are discussed.

ISSN:1049-8885    

DOI:10.1902/jop.1984.55.2.78

出版商:Wiley    

年代:1984

数据来源: WILEY

摘要:

Pockets were surgically createdin the two upper external incisors of four beagle dogs, and a copper band adapted to prevent reattachment. After 4 weeks the copper bands were removed, the teeth scaled and root‐planed and crowns placed on both experimental teeth in such a way that one of them was forced bucally when the teeth occluded. An orthodontic appliance anchored in bands cemented to the cuspid teeth brought the tooth back to its original position when disclusion occurred. Experimental time was 12 weeks. Clinical indices and bacterial samples for darkfield examination were taken at baseline and weekly thereafter. The dogs were fed a diet that favored plaque accumulation and no oral hygiene was performed. Surgically created pockets initially became populated by cocci (65%‐75%) and small amounts of motile bacteria (12%‐15%) including 3% to 4% spirochetes. In 4 weeks the percentage of cocci declined steadily (42%‐45%) and motile bacteria increased to 37% to 43% with spirochetes representing 24% to 27%. After scaling and root planing, the number of cocci increased again and motile bacteria declined although the baseline values were not reached. This decline persisted for 2 weeks after scaling. Repopulation of the pocket in traumatized and nontraumatized teeth followed the same initial pattern, taking again 5 weeks to return to prescaling levels. No difference was found between traumatized and nontraumatized teeth. Clinical measurements, however, revealed a statistically greater loss of attachment in traumatized teeth as compared with nontraumatized teeth.

ISSN:1049-8885    

DOI:10.1902/jop.1984.55.2.86

出版商:Wiley    

年代:1984

数据来源: WILEY

摘要:

Recent studies havedemonstrated an association ofEubacteriumsp. with the subgingival microflora of patients with chronic periodontitis. One species,Eubacterium brachy, was evaluated to determine the possible mechanisms by which this microorganism may contribute to this disease. An extracellular antigen was identified in the culture supernatant which reacted with antibodies in human sera. This antigen was isolated by methanol precipitation and purified by gel filtration. The purified extracellular antigen was reactedin vitrowith45CaCl2‐labeled fetal rat bone in a bone resorptive bioassay. This antigen was shown to have a molecular weight of 170,000, to share a line of identity with a sonicated preparation ofE. brachywhole cells and to result in increased45CaCl2release from fetal rat bones when cultures were exposed to the purified extracellular antigen at concentrations of 10 to 53μg/ml.

ISSN:1049-8885    

DOI:10.1902/jop.1984.55.2.93

出版商:Wiley    

年代:1984

数据来源: WILEY

摘要:

An odontogenic keratocystwhich was in a lateral periodontal location is reported. The histology of the odontogenic keratocyst is compared with that of the lateral periodontal cyst. The importance of correctly diagnosing the odontogenic keratocyst is stressed, especially in view of its high recurrence rate and its possible association with the basal cell nevus syndrome.

ISSN:1049-8885    

DOI:10.1902/jop.1984.55.2.98

出版商:Wiley    

年代:1984

数据来源: WILEY

摘要:

Standard wounds of simpleincision and trauma were made in the gingivae of monkeys. The healing from the 1st to the 21st day was described clinically, his'tologically, physically and biochemically. There were no major clinical differences, but both atraumatic and traumatic wounds have reactions in the periodontium to be considered in postoperative care.

ISSN:1049-8885    

DOI:10.1902/jop.1984.55.2.103

出版商:Wiley    

年代:1984

数据来源: WILEY

摘要:

Neutropenia is a transientor chronic blood disorder characterized by a decrease in the number of circulating polymorphonuclear leukocytes (PMNs). Neutrophils are a major cellular defense against infection, and depletion of these cells is potentially fatal. Stomatitis and gingivitis frequently are seen in patients with neutropenia. Therefore, the diagnosis of severe oral pathoses of obscure origin must include a differential white blood cell count. The importance of the dentist's role is dramatically illustrated in the rare case reported here, since the oral condition was the reason for this patient's definitive blood work‐up. The report illustrates the importance of the laboratory assessment in dental patients with unusual periodontal destruction or other inexplicable oral changes.

ISSN:1049-8885    

DOI:10.1902/jop.1984.55.2.114

出版商:Wiley    

年代:1984

数据来源: WILEY