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1. |
Transfer Factor in Mycosis fungoides: Three Years Experience |
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Dermatology,
Volume 160,
Issue 1,
1980,
Page 1-6
H. Zachariae,
J. Ellegaard,
E. Grunnet,
K. Thestrup-Pedersen,
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摘要:
13 patients with clinically and histologically verified mycosis fungoides were treated with transfer factor as additional therapy to the hitherto conventional treatment after this had failed. After approximately 3 years, complete remission was present in 3 patients, 4 patients were significantly improved and registered as being in partial remission, while the condition was registered as no change in 3 patients. 1 patient was found worse, 1 patient had died after discontinuation of therapy and 1 patient was out of the study. In this case treatment was withdrawn because of the development of contact urticaria to nitrogen mustard, her basic therapy. The number of T lymphocytes, which was low prior to treatment, increased to normal values during the therapeutic period. During the first year a decrease in serum IgE was noted. The results of the clinical evaluation seem to indicate that transfer factor may be of value as an additional therapeutic agent in mycosis fungoides. Controlled investigations are needed and are in progress.
ISSN:1018-8665
DOI:10.1159/000250459
出版商:S. Karger AG
年代:1980
数据来源: Karger
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2. |
Effect of Cyproterone Acetate Orally on Hair Density and Diameter and Endocrine Factors in Women with Idiopathic Hirsutism |
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Dermatology,
Volume 160,
Issue 1,
1980,
Page 7-16
J.D.R. Peereboom-Wynia,
J.C. Boekhorst,
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摘要:
The effect of oral cyproterone acetate on hair density and diameter was studied in a clinically homogeneous group of 11 women with idiopathic hirsutism. Therapy was continued for 12 cycles of treatment. Hair density and mean hair diameter on the chin and left upper leg were measured before, immediately after and 3 months after therapy. Generally, the effect of treatment consisted of a quantitative reduction of both parameters, but the effect was not permanent after termination of therapy. Concurrently, the possible influence on plasma androgen was studied. No significant differences were found between the concentrations of plasma testosterone, dehydroepiandrosterone and androstenedione before and after treatment.
ISSN:1018-8665
DOI:10.1159/000250460
出版商:S. Karger AG
年代:1980
数据来源: Karger
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3. |
HLA Antigens in Atopic Dermatitis |
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Dermatology,
Volume 160,
Issue 1,
1980,
Page 17-20
Schultz Larsen,
N. Grunnet,
P. Vase,
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摘要:
The HLA antigens in a family with atopic dermatitis were studied. All family members with atopic dermatitis had haplotype A2, Bw35, Cw4. It has been recently demonstrated that HLA type Bw35 is found with an increased frequency in atopic dermatitis. There appears to be an inconsistent and weak correlation between atopic dermatitis and HLA-A, HLA-B and HLA-C loci.
ISSN:1018-8665
DOI:10.1159/000250461
出版商:S. Karger AG
年代:1980
数据来源: Karger
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4. |
Epidermal Ridge Disarrangement and Hamman-Rich Syndrome |
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Dermatology,
Volume 160,
Issue 1,
1980,
Page 21-24
D. Aderka,
M. Eldar,
Y. Shoenfeld,
M. David,
E. Feuerman,
B.M. Katzenelson,
J. Pinkhas,
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摘要:
A patient with Hamman-Rich syndrome and palmo-plantar disarrangement of the epidermal ridges is reported. The significance of this association is discussed.
ISSN:1018-8665
DOI:10.1159/000250462
出版商:S. Karger AG
年代:1980
数据来源: Karger
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5. |
Circulating Immune Complexes in Systemic Scleroderma and Generalized Morphea |
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Dermatology,
Volume 160,
Issue 1,
1980,
Page 25-30
Sean O’Loughlin,
Gerhard Tappeiner,
Robert E. Jordon,
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摘要:
There is growing evidence that pathologic changes in the vascular system are implicated in the pathogenesis of systemic scleroderma. It has been suggested that immune complex deposition may be responsible for such changes. We measured circulating immune complexes in 10 patients with severe systemic scleroderma, 1 of whom had clinical evidence of renal disease, and in 3 patients with generalized morphea. None of the patients had significantly elevated levels. Our findings suggest that although circulating immune complexes are of diagnostic and prognostic value in other collagen vascular diseases, they do not play a major role in the pathogenesis of systemic scleroderma in patients who lack clinical evidence of renal disease.
ISSN:1018-8665
DOI:10.1159/000250463
出版商:S. Karger AG
年代:1980
数据来源: Karger
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6. |
Lepromatous Leprosy and Contact Dermatitis |
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Dermatology,
Volume 160,
Issue 1,
1980,
Page 31-36
J. Jerez,
E. Quintanilla,
D. Martin-Gil,
C. Ayesa,
A. Oehling,
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摘要:
The rare association of lepromatous leprosy and allergic contact dermatitis due to chromium in cement was confirmed clinically and biologically in a male patient. The apparent lack of influence of lepromatous leprosy on the development and maintenance of this dermatitis dependent upon cell-mediated immune mechanisms is discussed.
ISSN:1018-8665
DOI:10.1159/000250464
出版商:S. Karger AG
年代:1980
数据来源: Karger
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7. |
A Peculiar Case of Sporotrichosis |
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Dermatology,
Volume 160,
Issue 1,
1980,
Page 37-40
Hiroshi Hachisuka,
Yoichiro Sasai,
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摘要:
A case of localized cutaneous sporotrichosis is reported. The lesion was granulomatous, without lymphatic metastasis. Histological examination revealed numerous spores and asteroid bodies. Sporotrichin reaction was negative, but after treatment with potassium iodide became positive. The peculiar features of this case seem to be due to some disturbances of cellular immunity.
ISSN:1018-8665
DOI:10.1159/000250465
出版商:S. Karger AG
年代:1980
数据来源: Karger
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8. |
Dermatitis herpetiformis and Vitiligo |
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Dermatology,
Volume 160,
Issue 1,
1980,
Page 41-44
Poul Ølholm-Larsen,
Gunnar Kavli,
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摘要:
A 36-year-old woman developed vitiligo in areas with active dermatitis herpetiformis. Both diseases have been associated with autoimmune disorders. However, in the present case the vitiligo is believed to be an isomorphic reaction to the dermatitis herpetiformis lesions.
ISSN:1018-8665
DOI:10.1159/000250466
出版商:S. Karger AG
年代:1980
数据来源: Karger
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9. |
Woringer-Kolopp Disease |
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Dermatology,
Volume 160,
Issue 1,
1980,
Page 45-56
A. Aliaga,
J.A. Bombi,
E. Barbera,
J.M. Fortea,
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摘要:
For the purpose of describing a new case of the Woringer-Kolopp disease, we are up-dating the problem and its classification and contributing clinical, histopathological, and ultrastructural facts which show that this is a lymphoma of the T cells and therefore should be classified along with the mycosis fungoides and the Sézary syndrome. The identification test of the lymphocytes and the ultrastructural study bring to light new facts of this disease
ISSN:1018-8665
DOI:10.1159/000250467
出版商:S. Karger AG
年代:1980
数据来源: Karger
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10. |
Scopulariopsis onychomycosis Treated with Natamycin |
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Dermatology,
Volume 160,
Issue 1,
1980,
Page 57-61
Per Onsberg,
Dorrit Stahl,
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摘要:
7 patients with Scopulariopsis brevicaulis onychomycosis of the toe-nails were treated locally with 1% natamycin in 60% dimethylsulphoxide. After 3–5 months treatment the fungus could no longer be isolated from the nails, and at follow-up 15 months after the completion of the treatment, 2 patients reported permanent improvement of the nails and 3 a complete cure. In 1 patient the treatment was ineffectiv
ISSN:1018-8665
DOI:10.1159/000250468
出版商:S. Karger AG
年代:1980
数据来源: Karger
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