ISSN:1018-8665    

DOI:10.1159/000250228

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

In 16 out of 18 patients with rosacea, mites of the species Demodex folliculorum were isolated in mostly great numbers from lesions of the facial skin. In patients with perioral dermatitis, the mite was demonstrated in 17 out of 29 patients. All patients, however, including those where no mites were found, could be completely cured by nightly application of hexachlorocyclohexane 0.25% (Jacutin®). The average treatment time was 7 weeks for rosacea and 5 weeks for perioral dermatitis. 2 patients with rosacea and 4 patients with perioral dermatitis relapsed, but cleared again after treatment was repeated. The initial flare-up of the dermatitis, which is observed regularly after starting the Jacutin-therapy, is described. Quantitative aspects of Demodex infestation and its histopathologi-cal alterations are discussed in relation to present-day knowledge

ISSN:1018-8665    

DOI:10.1159/000250229

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

In 10 cases of cutaneous lymphomas, outflow of nuclear material into the cytoplasm of tumoral cells was observed ultrastructurally. Various stages of this phenomenon could be visualized. These observations were made in various types of epidermotropic and non epidermotropic cutaneous lymphomas but they are particularly evident in Crosti’s reticulosis. These nuclear abnormalities were observed prior to any treatment; they are unrelated with tissue preparation and are very different from the well-known nuclear degeneration processes. They have been observed in various but exceptional physiological or pathological conditions, but have apparently not been noticed in earlier works on cutaneous lymphomas, except in 1 case of Crosti’s reticulosis. No prognostic implication of these images was found. Their significance is not clear, but could be related with mitotic disord

ISSN:1018-8665    

DOI:10.1159/000250230

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

A 19-year-old male had chronic mucocutaneous candidiasis with typical granuloma on the face, scalp and genital area. He had defects in cell-mediated immunity (cutaneous anergy to common antigens, but normal number of T lymphocytes and normal lymphocyte transformation with phytohemagglutinin), and there were no endocrine deficiencies. He had systemic involvement, including lungs, kidneys, liver and spleen diagnosed by radiologic studies. In the histologic findings of the skin, typical features were seen of Candida granuloma lesions, and hyphae and spores of Candida albicans also were identified in the Malpighian layer. Therapy with 5-fluorocytosine resulted in a remarkable improvement.

ISSN:1018-8665    

DOI:10.1159/000250231

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

Oxatomide was evaluated in a double-blind study of 35 patients with chronic urticaria. For 5 weeks patients received at random either 30 mg oxatomide b.i.d. or a placebo. Oxatomide significantly reduced not only the duration of the attacks but also the severity of erythema, lesions and itching. This lower level of suffering was clearly reflected by a diminished need for additional antiallergic medication. The overall response to treatment was rated excellent or good in 72% of the oxatomide-treated patients against only 23% of the controls which is a significant difference. Sleepiness was reported in 1 patient of each group.

ISSN:1018-8665    

DOI:10.1159/000250232

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

1,322 melanoma patients in the clinical stage I were followed up for at least 8 years. The females clearly predominated (sex ratio f :m = 2.2:1). Trunk melanomas prevailed in males and extremity melanomas in females. The overall survival was strikingly better in females than in males. In 936 of the patients exhibiting ‘high risk’ melanomas, tumors located on the upper extremities and on the lower extremities gave the relatively best 8-year-survival rates (60.7% resp. 62.7%). 8-year-survival rates decreased if head (52.8%) and trunk locations (40.3%) were involved. As to these anatomic sites of the primary tumor, there were no statistically relevant differences between the survival rates of the females and the males. Thus, the anatomic site of malignant melanoma is especially important for the prognosis largely explaining the sex differences of the overall survival ra

ISSN:1018-8665    

DOI:10.1159/000250233

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

In this paper, we describe a case of lichen planus of the mouth with intense melanosis, in a middle-aged white male. Due to its unusual clinical characteristics, we believe that this case represents a rare variant of lichen planus of the oral mucosa. The histopathologic findings, differential diagnosis and its possible connection with lichen planus pigmentosus of the skin are discussed.

ISSN:1018-8665    

DOI:10.1159/000250234

出版商:S. Karger AG    

年代:1981

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000250235

出版商:S. Karger AG    

年代:1981

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000250236

出版商:S. Karger AG    

年代:1981

数据来源: Karger