摘要:

Abstract:Use of the FA6 criteria for the diagnosis of acute erythroleukaemia (AEL). R. K. Woodruff, I. H. Bunce, S. Johnson, A. in. Paxton and J. S. malpas,Aust. N.Z. J. med., 1981, 11, pp. 1–7.The criteria proposed by the French‐American‐British (FAB) Group for the diagnosis of acute erythroleukaemia (AEL), including the requirement for ≥ 30% marrow myeloblasts, were used in a review of patients with erythroleukaemia. Ten patients with AEL were identified, and a further twelve patients with marrows suggestive of AEL but having<30% myeloblasts were classified as having refractory anemia with excess of blasts (RAEB). The AEL patients had a poor prognosis, poor response to chemotherapy, and none showed evolution to myeloblastic or monoblastic leukaemia. In contrast, the patients with RAEB appeared to survive longer, respond better to chemotherapy, and several evolved into typical myelogenous leukaemiaThe FAB criteria subdivides patients with erythroleukaemia into groups with apparent clinic pathological and prognostic differences. Further studies using these or equally strict criteria are

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03728.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Abstract:The management of ascites using the rhodiascit apparatus (“Paris Pump”). G. H. Radvan, B. A. Chapman and B. P. Billington,Aust. N.Z. J. med., 1981, 11, pp. 12–15.The Rhodiascit Apparatus (“Paris Pump”) which ultrafilters sodium and water from ascitic fluid allowing rein fusion of a protein‐rich concentrate, has been found to be a valuable procedure in the management of ascites associated with liver cirrhosis. The device was evaluated in eight patients with the aim of rapidly controlling ascites with minimum hospitalizationThe duration of the procedure varied from 8.5 to 55 hr (mean 27 hr) and resulted in a mean girth reduction of 13 cm (range 5–7 to 24 cm) and a mean weight loss of 13.6 kg (range 5 7 to 23 kg). Serum electrolytes and total protein were unchanged; a slight but insignificant rise in serum creatinine was observed. Three infective episodes occurred, but these were easily controlledThe procedure was, in general, well tolerated, inexpensive and allowed rapid relief of ascites with few

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03729.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Abstract:Presentation of unknown primary cancer with metastatic liver disease—management and natural history. R. A. Nesbit, in. H. N. Tattersall, R. in. Fox and R. L. Woods,Aust. N.Z. J. med., 1981, 11, pp. 16–19.Initial blind liver biopsy established a histological diagnosis of metastatic cancer in 27 out of 34 patients who presented with clinical signs of liver metastases and no obvious primary tumour. Twenty‐two of the patients had meta static adenocarcmoma, and a primary tumour site was identified before death in only four pa

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03730.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Abstract:Some aspects of the natural history of subarachnoid haemorrhage. D. Christie,Aust. N.Z. J. med., 1981, 11, pp. 24–27.In a population‐based stroke incidence study, 27 cases of subarachnoid haemorrhage were identified, an incidence rate of 26.4/105person years at risk. Subarachnoid haemorrhage comprises but a small part of the burden of cerebrovascular disease, but all appear to be admitted to general hospitals. The overall survival rate was 44% to six months, in those cases treated surgically the survival rate was 63%. Of more importance, by six months only 19% were free of residual handicap; in terms of this endpoint, those cases treated surgically were at no advantage as compared with those treated conservati

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03731.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Abstract:Patient initiated implantable pace makers for paroxysmal supraventricular tachycardia. J. Vohra, A. Hamer, H. Mond, G. Sloman and D. Hunt,Aust. N.Z. J. Med., 1981, 11, pp. 27–34.Seven patients with recurrent paroxysmal supraventricular tachycardia (PSVT) resistant to standard drug therapy were treated with patient initiated implantable pacemakers. All patients had required frequent hospital admissions and cardio versions prior to pace maker implantationTwo patients had Wolff‐Parkinson‐White (WPW) syndrome on their surface ECGs and five patients had no ECG evidence of pre excitation. All patients had detailed electrophysiological studies. Three patients had junctional tachycardia, one patient had reciprocating atrial tachycardia and in three, including one with normal surface ECG, retrogradely conducting accessory atrio‐ventricular connections (AAVC) formed a part of the tachycardia circuit. Initiation and termination of tachycardia were re‐checked at subsequent studiesOn the basis of these studies, two patients with WPW syndrome had right ventricular endocardial leads and custombuilt, magnet actuated pacemakers capable of delivering right ventricular coupled stimuli at fixed, present intervals of 200 and 400 ins. Both these pacemakers provided inconsistent reversions and proved unsatisfactoryIn the remaining five patients, a unipolar tined J‐shaped right atrial (RA) lead (Medtronic ‡‡ 6991) and a radiofrequency (RF) receiver (Medtronic 5998T) were implanted and enabled patients to overdrive PSVT. The follow‐up period in these patients ranged from 14 to 20 months. Several episodes of PSVT have been consistently reverted and none have required hospitalisation or cardio‐version. Two patients had transient atrial fibrillation following the application of RF pacemaker. Three have required no antiarrhythmic drugs and in two the drug therapy has been greatly reduced and simplified. The Medtronic 6991 lead provided satisfactory RA stimulation without dislodgement.In carefully selected patients with PSVT, RF pacemakers provide a usef

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03732.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Abstract:Beta adrenoreceptor‐blocking drugs once daily in essential hypertension: a comparison of propranolol, pindolol and atenolol. J. D. F. England,Aust. N.Z. J. Med., 1981, 11, pp. 35–40.Atenolol, Pindolol and Propranolol in single daily doses administered to 18 selected patients with Mild essential hypertension achieved adequate control of blood pressure. Chlorothiazide had been initially administered twice a day without full control of blood pressure and this diuretic therapy was continued unaltered throughout the studyMethacholine challenge testing of respiratory function was performed during the placebo phase and with each beta adrenoreceptor‐blocking drug. In the 18 nonasthmatic patients, the reduction in FEVl, was significant only for propranolol therapy when coinpared to placeboEach beta adrenoreceptor‐blocking drug was associated with small, but significant, increases in fasting plasma triglyceride concentrations and suppression of fasting immuno‐reactive glucagon conc

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03733.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Abstract:The antibody response to Brucella: immunoglobulin response measured by enzymelinked immunosorbent assay and conventional tests. G. L. Gilbert and L. A. Hawes,Aust. N.Z. J. Med., 1981, 11, pp 40–45.An enzyme‐linked immunosorbent assay was adapted to measure total and individual classes of brucella antibody. The results were compared with those of conventional tests for brucella antibody on the sera of a number of healthy seropositive abattoir workers and several patients with either acute or suspected chronic brucellosis. IgG was the class of brucella specific immunoglobulin most commonly detected in all groups. IgM was present in the sera of 40% of seropositive abattoir workers, all but one of the patients with recent acute brucellosis or seroconversion and none of those with suspected chronic brucellosis. Many of the abattoir workers' sera which contained brucella specific IgM gave negative results in the direct agglutination test. The presence of brucella specific lgM in the sera of these men was, in most cases, associated with no past history of acute brucellosis and a relatively short period of employment in the abattoir. It is suggested that the presence of brucella specific IgM in the serum of a person occupationally exposed to 6. abortus, probably indicates a relatively recent primary infection, either symptomatic or sub clinical and has no prognostic significance. Repeated or prolonged exposure is associated with IgG brucella antibodies, often in high titre, irrespective of symptoms. It was not possible, on the basis of any serological tests performed in this study to distinguish healthy people exposed to brucella from those with symptoms consistent with chronic brucell

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03734.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Abstract:Bile acid metabolism in mild arteriohepatic dysplasia*. D. M. Collins, F. T. Shannon and C. B. Campbell,Aust. N.Z. J. Med., 1981, 11, pp. 48–51,Arteriohepatic dysplasia is a rare congenital syndrome in which attenuated peripheral pulmonary arteries are associated with liver impairment, The earliest indication is usually persistent cholestatic jaundice in the first few months after birth. Although this is invariably associated with pruritus, bile acid kinetic studies have not been reported in such patients. This report describes a girl with a particularly mild form of the syndrome who was never observed to be clinically or biochemically jaundiced. Bile acid studies indicated that there was a defect in bile acid excretion but not in uptake or conjugati

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03735.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Abstract:Dermatomyositis and the nephrogenic hepatic dysfunction syndrome. R. G. Reiner, W. D. Parry, R. Bowey, E. Chandra and A. Kerr Grant,Aust. N.Z. J. Med., 1981, 11, pp. 52–55.Two uncommon associations of a renal malignancy occurring in an elderly male are described. A localized dermatomyositis and non‐meta static abnormal liver functions were features of this otherwise occult neop

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03736.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Abstract:A problem of management in Whipple's Disease. K. P. Lim, A. S‐Y Leong and A. Kerr Grant,Aust. N.Z. J. Med., 1981, 11, pp. 5&59.A patient with Whipple's disease did not respond to appropriate antibiotic treatment. A therapeutic response was obtained by a combination of tetracycline and prednisolo

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03737.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY