ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1967.tb03351.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1967.tb03352.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1967.tb03353.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

摘要:

SummaryPigs of the Hampshire and Duroc breeds were subjected to bloodtyping. An anomaly of inheritance affecting the E blood‐group system was detected in one pig among 10056 progeny from 1171 matings. AnE1E3Hampshire male was mated with anE1E1Hampshire female. The male had been exposed to 300 r of gonadal X‐irradiation. Thirteen pigs were born. Six pigs wereE1E1, six wereE1E3, and one appeared to beE1E2.The exceptional bloodtype might be a result of mutation, interallelic recombination or gene interaction. These hypotheses are discus

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1967.tb03354.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

摘要:

SummarySeven cases, in which the presence of a blood group iso‐antibody was unsuspected until several days after transfusion, are described. In one case the rapid appearance of multiple antibodies produced signs and symptoms simulating auto‐immune haemolytic anaemia. In two of the seven cases, antibodies were detectable in the pre‐transfusion serum only when cells containing a double dose of the corresponding antigen were

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1967.tb03355.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

摘要:

SummaryStudies were made on the inhibitory effects of various substances on haemagglutination due to immune adherence of sheep erythrocyte‐antibody‐complement complexes (EAC′) to human erythrocytes. Two methods of measuring inhibition were tested. The more satisfactory of these was semi‐quantitative and involved determination of the number of EAC′ complexes, formed with a fixed amount of complement, required to produce immune adherence haemagglutination in the presence and in the absence of inhibitor. Ghosts prepared by lysis of normal human erythrocytes in distilled water or by freezing and thawing inhibited immune adherence haemagglutination. Ghosts from non‐reactive animal or human erythrocytes or from papain‐treated human erythrocytes did not inhibit immune adherence haemagglutination. Ageing of erythrocytesin vitrowas accompanied by loss of inhibitory power of ghosts prepared from them. Some mucoids extracted from human erythrocytes and most samples of mucopeptides extracted from human erythrocytes were inhibitory. Comparison of the inhibitory power of ghosts and mucopeptides indicated that considerable loss of activity occurred during extraction. It is suggested that the immune adherence receptor was partially degraded during extraction and that the mucopeptides acted as ‘incomplete analogues' of the receptor. It is considered more likely that the immune adherence receptor lies in the peptide part of such material than in the carbohydrate part. Neuraminic acid had no inhibitory activity. Active inhibitors were also extracted from bovine erythrocytes and human platelets, which do not react in immune adherence. The possibility is suggested that the immune adherence receptor may be present but masked or present in incomplete form on some non

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1967.tb03356.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1967.tb03357.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1967.tb03358.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1967.tb03359.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1967.tb03360.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY