ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1989.tb00328.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

The effectiveness, feasibility and credibility of a computer assessment package was evaluated in a group of 60 neuro‐otological outpatients. The computer system was compared with a standard questionnaire and used to elicit basic neuro‐otological information prior to clinicla interview. The majority of patients (81%) preferred computer assessment. There were no differences in attitude or difficulties between diagnostic groups. Older patients had more difficulties and took longer than younger patients. The computer system was also more efficient than the form from an information handling and administrative point of v

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1989.tb00329.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Twelve specimens of tympanosclerosis were examined. Six were immediately fixed in 3% glutaraldehyde and 6 were obtained from the departmental collection of specimens in wax blocks which had previously been examined by light microscopy. Seven specimens were demineralized. The material was examined macroscopically, by light microscopy and by scanning electron microscopy to a magnification of x 25000. The microstructure of tympanosclerosis is an irregular three‐dimensional collagen lattice, enclosing distinct, spherical, mineralized aggregates, housed in lacunar‐like spaces. This lattice is continuous with the plaque surface which is an envelope, probably of proteinaceous material. The spherical calcified aggregates were absent from the demineralized specimens. There was no structural difference in the scanning electron microscopic appearances of specimens processed conventionally in 3% glutarldehyde and those previously embedded in

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1989.tb00330.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Between 1978 and 1981, 85 patients with advanced squamous cell carcinoma of the head and neck were randomized to receive induction VBM followed by radiotherapy, or radiotherapy alone. The shortest follow‐up is thus 6 years. The median survival of patients receiveing induction chemotherapy was 46 weeks, that of the radiotherapy group alone was 75 weeks. As the two groups were not balanced despite randomization, multivariate methods (GLIM) were used to identify significant prognostic factors. These were: response to radiotherapy (P<0.001), nodal status (P<0.001), age (P<0.01), and histological grade (P<0.01). Neither treatment with, nor response to, chemotherapy had a significant effect on surviva

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1989.tb00331.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Four non‐prescription cerumenolytic agents were acquired over the counter of a high‐street chemist and evaluated along with Sodium Bicarbonate ear drops BP, olive oil, distilled water, and acetone in an in‐vitro study. Sodium Bicarbonate ear‐drops BP are used by the nurses in the department and are recommended in the British National Formulary as the most effective solution to soften cerumen prior to syringing.1Acetone was included as an effective organic solvent. The test was performed in a water bath, controlled to match the temperature of the external auditory meatus. Disintegration of the cerumen was noted over a two‐hour period. Substantial disintegration occurred with three products: Waxsol, Stores Own Brand, and distil

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1989.tb00332.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

This study was performed to examine the relationship between the pre‐operative radiographic platal airway and no peak‐peak tympanometric conversion 1 yr following adenoidectomy, adenotonsillectomy or no pharyngeal surgery performed for otitis media with effusion. A relationship between the airway in children with otitis media with effusion and matched controls is described and this is used to analyse tympanometric change in 3 airway size groups. No peak‐peak conversion was significantly greater following adenoidectomy or adenotonsillectomy compared with no pharyngeal surgery in those with small airways and tonsillectomy conferred with no additional benefit. Adenoidectomy with or without tonsillectomy is probably best avoided in children with large radiographic palatal airway measurements when planning surgical treatment for established disease, although this may ultimately be related to age at oper

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1989.tb00333.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

We present a prospective randomized study comparing two approaches for outpatient antroscopy. The traditional inferior meatus route was seen to be associated with a higher incidence of discomfort and significant complications. An alternative route via the canine fossa provided easier access, better patient tolerance and improved visualization of the antral contents. It was associated with a lower incidence of immediate complications, although there were a number of delayed symptoms, all of which were mild and transient. The canine fossa approach under local anaesthesia offers an effective and more acceptable alternative for antroscopy as an out‐patient procedur

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1989.tb00334.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

For many years it has been suggested that the subjective outcome of the operation of submucosal diathermy to the inferior turbinates (SMD) may be predicted by preoperatively testing the ability of the nasal mucosa to decongest with topical vasoconstrictor agents. This study of 22 patients undergoing SMD, confirms that the pre‐operative decongestion produced by xylometazoline is both a good subjective (P<0.001) and objective (P<0.002) predictor of outcome. If a significant reduction in nasal resistance is achieved by the application of topical decongestants, then the operation of SMD is likely to be effectiv

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1989.tb00335.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

While the origins of sudden sensorineural hearing loss remain unproven and treatment empirical, the most appropriate therapy remains a matter of controversy. In this paper we have analysed the current forms of treatment, i.e. diatrizoate meglumine, steroids and a vasodilator. The results suggest that although several related factors were shown to indicate a good prognosis regardless of the therapy, none of the currently available regimens produces consistently better results than the spontaneous recovery rate of 65% reported by Mattox&Simmons.1

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1989.tb00336.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

The peripheral blood lymphocyte counts of 333 patients with a nasopharyngeal carcinoma and 125 control subjects were compared. The mean pretreatment lymphocyte count in the patients was significantly lower than that of the normal controls (P<0.0001). Subgroup analysis of absolute lymphocyte counts in different stages of the disease revealed a stage dependent lymphopenia which became significant when the disease was stage III or over (P<0.0001). Characterization of peripheral blood lymphocyte subsets in 81 patients and 46 normal control subjects revealed a significant reduction of the absolute Pan T (T11) lymphocytes in the patients (P<0.0001). Both the absolute numbers of T helper (T4) and suppressor cells (T8) were reduced in the patients (P<0.0001 and<0.026, respectively). While the percentage of T4 was reduced (P<0.0001), the percentage of T8 was elevated (P<0.02), resulting in a reduced T4/T8 ratio (P<0.0001). The mean absolute and percentage counts of T11, T8 and B did not correlate with different stages of the disease.

ISSN:0307-7772    

DOI:10.1111/j.1365-2273.1989.tb00337.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY