ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

摘要:

The clinical reactions and immunologic responses to twoHaemophilus influenzaetype b capsular polysaccharide vaccines were studied in 24− to 36-month-old children. A candidate vaccine (Connaught) induced ≥ 1.0 μg/ml of antipolysaccharide antibody in 37 (61.7%) of 60 infants 24 to 26 months of age; this compared with 8 (38.1%) of 21 infants 24 to 36 months of age given a licensed vaccine (Praxis). Reactions to both vaccines within 24 hours of administration were minimal; a smaller percentage of recipients of the candidate vaccine were asymptomatic (P< 0.05). The lower levels of antibody production than previously reported may necessitate a reevaluation of current recommendations.

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

摘要:

We reviewed the charts of 59 pediatric and adult patients hospitalized because of animal bites (46 dog bites, 10 cat bites, 3 monkey bites). The bites of 40 of the 59 patients were infected at the time of admission. Gram-stained specimens correctly predicted the infecting bacteria in only 5 of 20 cases. Eighty-three percent of the bacterial isolates were penicillin-susceptible. Before admission 14 patients had received outpatient antibiotic prophylaxis and the infections in 11 of these 14 patients were caused by bacteria susceptible to the prophylactic antibiotic. Complications were more common if antimicrobial therapy had not been altered according to susceptibility testing results. Of the 59 patients 19 were admitted immediately after being bitten because of severe uninfected bites. Of these 19 patients 18 received prophylactic antibiotics and none developed a serious complication.

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

摘要:

Aspirates from bite wounds in 39 children (21 with animal bites and 18 with human bites) were cultured for aerobic and anaerobic bacteria. Aerobic bacteria only were recovered in 7 (18%) wounds, anaerobic bacteria only in 3 (8%) and mixed aerobic and anaerobic bacteria in 29 (74%). A total of 59 isolates was recovered from animal bites (2.8/specimen): 37 aerobes (1.8/specimen); and 22 anaerobes (1.0/specimen). A total of 97 isolates were recovered from human bites (5.4/specimen): 44 aerobes (2.4/specimen); and 53 anaerobes (3.0/specimen). The most frequent isolates in both types of wounds wereStaphylococcus aureus, anaerobic cocci andBacteroidesspp. Present only in animal bites werePasteurella multocida, Pseudomonas fluorescensand M-5. Present only in human bites were Group A streptococci. Eighteen beta-lactamase-producing organisms were isolated in 16 wounds. This study demonstrates the polymicrobial aerobic-anaerobic nature of human and animal bite wounds.

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

摘要:

There is little information available regarding the impact of varicella among healthy children. A group of 137 households, identified by the County of Los Angeles Department of Health Services, were interviewed by telephone and yielded 247 cases of varicella. There were no hospitalizations for complications. Rates for physician visits and telephone calls to health care providers were 0.5 and 1.0 per case, respectively. School days lost by cases and work days lost by well adults in the households were 8.7 and 0.5 per case, respectively. Varicella had a measurable impact of economic significance on our survey population. Our observations need to be extended and included in cost-benefit analyses of varicella vaccine.

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID

摘要:

The ability of the Streptozyme® test to identify significant antibody rises in 46 patients with streptococcal pharyngitis was comparable to, but no greater than, that of the antistreptolysin O or antideoxyribonuclease B test and inferior to that of the combined use of both the antistreptolysin O and antideoxyribonuclease B tests. Serum specimens were also simultaneously analyzed with three different lots of Streptozyme® reagent. Lot-to-lot variation in the reagent resulted in a significant difference in antibody titer for 18 (19%) of the 92 sera tested. Differences among the three lots also produced variation in determining whether a significant rise in titer had occurred from the acute phase to the convalescent phase serum for a given patient. These observations raise concerns about the standardization of the Streptozyme® reagent and document the need for precise identification and quantitation of the streptococcal antigens used in this product.

ISSN:0891-3668    

出版商:OVID    

年代:1987

数据来源: OVID