ISSN:0098-6569    

DOI:10.1002/ccd.1810010102

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1975

数据来源: WILEY

ISSN:0098-6569    

DOI:10.1002/ccd.1810010103

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1975

数据来源: WILEY

ISSN:0098-6569    

DOI:10.1002/ccd.1810010104

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1975

数据来源: WILEY

ISSN:0098-6569    

DOI:10.1002/ccd.1810010105

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1975

数据来源: WILEY

摘要:

AbstractDuring diagnostic cardiac catheterization of 20 patients, 19 of whom had coronary artery disease (CAD), left ventricular (LV) performance was assessed by both muscle function indices and pump function indices. Muscle function indices included max dP/dt, Vpm, Vce5, and Vmax, the latter derived from both total pressure (TP) and developed pressure (DP) using catheter‐tip manometry. Pump function indices included LV ejection fraction (EF) and percent abnormally contracting segment (ACS), determined from biplane LV angiography. Muscle and pump function indices were also compared to the presence of the S3(ventricular diastolic) gallop. Correlations existed between EF and Vmax (TP), EF and Vpm, percent‐ACS and Vmax(TP), and percent‐ACS and Vpm, with r values of 0.760, 0.777, −0.884, and −0.841, respectively. Vmax(TP) and Vpm also correlated quantitatively with the presence of the S3gallop (p<0.0005). Total pressure‐derived muscle function indices appear to adequately describe mean LV performance in patients with CAD and ACS, but these muscle function indices are probably highly dependent upon the size of the myoc

ISSN:0098-6569    

DOI:10.1002/ccd.1810010106

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1975

数据来源: WILEY

摘要:

AbstractSystemic heparinization has been advocated as preventive for thrombotic and embolic complications of arterial catheterization. To test this hypothesis, 95 patients undergoing coronary angiography via the percutaneous femoral arterial approach were randomized into heparinized and nonheparinized groups.Evaluation for thrombotic and embolic complications by clinical means and noninvasive electrical impedance flow measurements in the lower limbs was performed precatheterization, postcatheterization, and at 4 and 24 hr. Clinical data reveal loss of distal leg pulses in 11% (5/47) of the nonheparinized group, with two of these individuals developing signs of claudication and requiring embolectomy. No individuals (0/48) in the heparinized group lost distal leg pulses. Immediate, 4‐hr, and 24‐hr postcatheterization bloodflow was 12%, 10%, and 12% lower, respectively, in the catheterized limb of those in the nonheparinized group. At 24 hr 52% of the nonheparinized group had bloodflow levels lower than the precatheterization levels in the right (catheterized) extremity, while 2% (2/48) of the heparinized group had a similar reduction.One possible complication of excess bleeding was noted with heparin.It is concluded that systemic heparinization is safe and can be an important adjunct in the reduction of thromboembolic complications of percutaneous coronary angiogra

ISSN:0098-6569    

DOI:10.1002/ccd.1810010107

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1975

数据来源: WILEY

摘要:

AbstractThe inotropic action of tolbutamide previously demonstrated in vitro was evaluated in 15 nondiabetic subjects during diagnostic cardiac catheterization. Following bolus injection of 250 mg of tolbutamide intravenously, a rise of serum insulin and a slight fall of serum potassium were observed. Inotropic response was determined from significant fall in PEP/LVET ratio, significant fall of left ventricular end‐diastolic pressure, shift to an augmented function curve in work‐pressure relationships, and prominent rise of dP/dt values at comparable heart rates. The inotropic effect was greatest at 5–15 min with return to near control values at 30 min. An unusually marked inotropic response was observed in one subject. While the measurable net hemodynamic effect of tolbutamide in the human heart is small, its effect on ischemic and normal areas within the heart of a diabetic patient with atherosclerosis may be different. Thus, its ultimate effect on the diseased heart may be signif

ISSN:0098-6569    

DOI:10.1002/ccd.1810010108

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1975

数据来源: WILEY

摘要:

AbstractPreliminary experience with a new flow‐directed pediatric anglography catheter in 35 infants indicates that catheterization of all cardiac chambers and both great vessels can be accomplished without risk of perforation or major arrhythmia. Antegrade access to the aorta from the left ventricle via the foramen ovale reduced the need for retrograde arterial catheterization. The maneuverability of this balloon‐tipped catheter coupled with the ability to perform safely selective anglography at any site entered establishes a unique advantage over standard cardiac catheters now in use. The success with this catheter in performing right and left heart studies and the safety in its use promise to significantly reduce the risk of mechanical and angiographic accidents during the intracardiac investigation of critically ill Infants with congenital heart dise

ISSN:0098-6569    

DOI:10.1002/ccd.1810010109

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1975

数据来源: WILEY

摘要:

AbstractAngiographically “terminal” coronary arterial branches were counted in 100 normal coronary cineangiograms to investigate the possibility that three left ventricular wall regions might be defined by identifying patterns of arterial inflow. An average of 45% of the terminal branches were counted in the anterior region supplied by the anterior descending coronary artery; 25% were counted in the lateral region supplied by diagonal and obtuse marginal arteries, and 30% were counted in the inferior region supplied by the distal circumflex and distal right arteries. Based upon the hypothesis that blood flow through an artery is directly proportional to the number of small branches into which it ramifies, this approach affords an estimate of the relative contribution by individual coronary arteries to total left ventricular perfusion. This concept could prove useful in defining a quantitative grading system of coronary arterial Inflow obstruct

ISSN:0098-6569    

DOI:10.1002/ccd.1810010110

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1975

数据来源: WILEY

摘要:

AbstractRight ventriculography was used to assess the tricuspid valve in 61 patients with systolic murmur‐click syndrome. Systolic murmurs were present in 47 cases, and 32 had clicks. Mitral valve prolapse was present in 52 patients. Late systolic prolapse of the tricuspid valve was demonstrated in 32 patients (52.4%). In 9 cases, prolapse involved the tricuspid valve alone. In the systolic murmur‐click syndrome, prolapse may involve either or both of the atrioventricular val

ISSN:0098-6569    

DOI:10.1002/ccd.1810010111

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1975

数据来源: WILEY