1. |
A Note from the Editors and Publishers |
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Acta Haematologica,
Volume 69,
Issue 1,
1983,
Page 1-1
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ISSN:0001-5792
DOI:10.1159/000206828
出版商:S. Karger AG
年代:1983
数据来源: Karger
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2. |
Acknowledgement |
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Acta Haematologica,
Volume 69,
Issue 1,
1983,
Page 2-2
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PDF (128KB)
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ISSN:0001-5792
DOI:10.1159/000206829
出版商:S. Karger AG
年代:1983
数据来源: Karger
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3. |
Coexistence of α-Thalassemia and a New Pyruvate Kinase Variant: PK Fukien |
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Acta Haematologica,
Volume 69,
Issue 1,
1983,
Page 3-8
Ernest Beutler,
Linda Forman,
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摘要:
A 12-year-old male of Chinese ancestry had life-long hemolytic anemia attributed to α-thalassemia. Restriction endonuclease mapping of his DNA revealed that in reality, he had three α-globin loci, but he was homozygous for pyruvate kinase deficiency. The new pyruvate kinase variant carried by this patient was characterized and designated PK Fukie
ISSN:0001-5792
DOI:10.1159/000206830
出版商:S. Karger AG
年代:1983
数据来源: Karger
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4. |
Glutathione in Neutrophils from Human Infants |
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Acta Haematologica,
Volume 69,
Issue 1,
1983,
Page 9-14
Ronald G. Strauss,
Esther L. Snyder,
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摘要:
The concentration of total glutathione (GSH + GSSG) and its depletion during oxidant stress were studied in neutrophils obtained from human neonates, their mothers and adult controls to determine if the previously reported increased susceptibility of infant neutrophils to oxidant damage could be related to glutathione deficiency. We found the basal level of glutathione to be lower and the oxidant-induced depletion of glutathione to be greater in infant neutrophils than in cells obtained from the blood of the infants’ mothers and adult controls. In studies reported earlier, neutrophils from infants were found to be deficient in the oxidant protective enzymes glutathione peroxidase and catalase. These abnormalities, in a fashion similar to that observed for patients with congenital defects of glutathione and catalase metabolism, may render infant neutrophils prone to oxidant damage and consequent dysfunctio
ISSN:0001-5792
DOI:10.1159/000206831
出版商:S. Karger AG
年代:1983
数据来源: Karger
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5. |
Hemoglobin A1in Subjects with G-6-PD Deficiency During and After Hemolytic Crises Due to Favism |
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Acta Haematologica,
Volume 69,
Issue 1,
1983,
Page 15-18
Giovanni Maria Baule,
Dionisio Onorato,
Giuseppina Tola,
Gavino Forteleoni,
Tullio Meloni,
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摘要:
HbA1 was determined in 15 G-6-PD-deficient subjects during a hemolytic crisis with hemoglobinuria due to ingestion of fresh fava beans. The same G-6-PD-deficient subjects were studied again 4 months after the crisis, when they were asymptomatic. 15 normal healthy children served as controls. A statistically significant decrease in HbA1 was observed in the favic subjects during hemolytic crises compared with their values 4 months later and those of the control group.
ISSN:0001-5792
DOI:10.1159/000206832
出版商:S. Karger AG
年代:1983
数据来源: Karger
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6. |
Autoimmune Hemolytic Anemia Due to Immunoglobulin G with Anti-SdXSpecificity |
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Acta Haematologica,
Volume 69,
Issue 1,
1983,
Page 19-22
Jorge F. Denegri,
Amin A. Nanji,
Margaret Sinclair,
Gail Stillwell,
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摘要:
We report a case of autoimmune hemolytic anemia, in a 28-year-old man with a warm-reacting IgG antibody with anti-Sdx activity. The unusual characteristics of the patient included the dramatic response to steroids and relapse after 1 year of treatment. This likely reflects the presence of an underlying autoimmune abnormality.
ISSN:0001-5792
DOI:10.1159/000206833
出版商:S. Karger AG
年代:1983
数据来源: Karger
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7. |
Coexistence of Double Gammopathy (IgM Kappa and IgM Lambda) in the Serum of a Single Individual with Chronic Lymphocytic Leukemia |
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Acta Haematologica,
Volume 69,
Issue 1,
1983,
Page 23-31
H. Schipper,
Kenneth B. Orr,
Eric J. Bow,
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摘要:
We present here a case of chronic lymphocytic leukemia in association with both IgM kappa and IgM lambda gammopathy with apparent distinct localization. Detailed case presentation is included and discussion of the immunologic and clinical implications follows.
ISSN:0001-5792
DOI:10.1159/000206834
出版商:S. Karger AG
年代:1983
数据来源: Karger
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8. |
Immunological Phenotype Related to Acid Alpha-Naphthyl Acetate Esterase and Acid Phosphatase in Childhood Acute Lymphoblastic Leukaemia |
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Acta Haematologica,
Volume 69,
Issue 1,
1983,
Page 32-35
A.J.P. Veerman,
D.R. Huismans,
C.H. van Zantwijk,
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摘要:
In 83 children with acute lymphoblastic leukaemia (ALL) the immunological phenotype of the lymphoblasts was determined using E rosetting, monoclonal anti-T cell sera, surface immunoglobulin staining and common ALL antiserum. The data were compared with acid alpha-naphthyl acetate esterase (ANAE) and acid phosphatase (AP) cytochemical data. The vast majority of T-ALL cells proved to be ANAE-negative (30/31) and AP-positive (29/31). Null-ALL was always AP-negative (12/12), the ANAE reaction was sometimes positive (4/12). In common ALL, findings ranged from negative to positive for both enzymes. Two cases of B-ALL were ANAE-negative and AP-negative. Enzyme cytochemical determinations gave thus preferential patterns, especially for T-ALL and null-ALL. In common ALL, considerable heterogeneity was found, which may be a reflection of differences in maturation between different cases of common ALL.
ISSN:0001-5792
DOI:10.1159/000206835
出版商:S. Karger AG
年代:1983
数据来源: Karger
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9. |
Acute Myelomonocytic Leukemia and the French-American-British Classification |
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Acta Haematologica,
Volume 69,
Issue 1,
1983,
Page 36-40
D. Huhn,
L. Twardzik,
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摘要:
39 patients suffering from different subtypes of monocytic (M 5) and myelomonocytic (M 4) leukemia were analyzed retrospectively. In 8 cases a ‘transitional myelomonocytic variant’ was diagnosed; the leukemic cell in these patients is marked by morphological and cytochemical signs of monocytic and granulocytic precursors. As the correct diagnosis of this special subtype may be difficult, its place within the French-American-British (FAB) classification will be discus
ISSN:0001-5792
DOI:10.1159/000206836
出版商:S. Karger AG
年代:1983
数据来源: Karger
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10. |
An Artificial Circulation for the Study of Thrombolysis |
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Acta Haematologica,
Volume 69,
Issue 1,
1983,
Page 41-46
J.E. Walker,
V. Flook,
D. Ogston,
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摘要:
The construction of an artificial circulation for the study of thrombolysis allowing variation in fluid pressure and flow rate is described. The lysis of 125I-fibrin was not influenced by variation in pressure between 10 and 30 cm H2O, but was significantly faster at a flow rate of 25 ml/min than at 40 ml/min or 10 ml/min. At equivalent concentrations as assessed on fibrin plates tissue activator induced greater thrombolysis than urokinase. Thrombolysis by both activators was diminished in the presence of plasma.
ISSN:0001-5792
DOI:10.1159/000206837
出版商:S. Karger AG
年代:1983
数据来源: Karger
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