摘要:

Chronical course, splenomegaly and pancytopenia are characteristic for hairy cell leukemia. The main feature are so-called hairy cells in peripheral blood. This cells were investigated by cytological, cytochemical, histological and electron microscopical methods. Special cytoplasmic inclusions seem to be specific for this cell type.

ISSN:0001-5792    

DOI:10.1159/000208149

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Phagocytic activity of leukaemic blasts in 20 adults and 16 children suffering from acute leukaemia was studied in vitro by the use of ferrioxidsaccharate. Most frequently phagocytosing blasts were encountered in myelomonocytic leukaemias. The morphological character of positive blasts resembled often that of monocytoid cells. In lymphoblastic and reticular leukaemias phagocytic ability of blasts was an exceptional finding.

ISSN:0001-5792    

DOI:10.1159/000208150

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

In Hodgkin’s disease, blood cultures showed a close relationship between the rate of biastic transformation of PHA-stimulated lymphocytes and the number of macrophages appearing in unstim ulated cultures. Despite individual variations, in single cases the yield of macrophages agreed closely with the lymphocyte transformation rate. Results arediscussed in connection with hypothesis on the origin of macrophages in cultur

ISSN:0001-5792    

DOI:10.1159/000208151

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Blood lymphocytes of normal individuals and of patients with chronic lymphocytic leukemia were evaluated for their blastogenic response to insoluble PHA. In at least preferential stimulation of normal B-lymphocytes was observed, whereas leukemic lymphocytes were almost insensitive. This result supports the hypothesis of a functionally defective B-lymphocyte population in chronic lymphocytic leukemia.

ISSN:0001-5792    

DOI:10.1159/000208152

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Peripheral lymphocytes of 16 patients with chronic lymphatic leukemia were studied for B and T cell markers with peroxidase-labelled anti-immunogloulin antisera and complement and spontaneous rosetting techniques. Increased numbers of B cells and normal numbers of T cells were noted. A significant observation was the presence of a large proportion of circulating lymphocytes without the conventional markers for T and B cells. This finding is correlated with clinical features.

ISSN:0001-5792    

DOI:10.1159/000208153

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Previously we showed that von Willebrand patients could be separated into 2 groups on the basis of ristocetin-induced platelet aggregation and factor VIII (antigen and activity). Ristocetin-induced platelet aggregation and factor VIII exhibited a positive correlation. This paper deals with 5 out of 31 examined von Willebrand patients in which ristocetin-induced platelet aggregation was not in correlation either with factor VIII activityor antigen. The importance of these findings is discussed.

ISSN:0001-5792    

DOI:10.1159/000208154

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

In a 53-year-old female patient, a tumor localized in the nasopharyngeal cavity together with hematologic features of acute paramyeloblastic leukemia were observed. More than 70% blast cells contained giant intracytoplasmic inclusions which have been found to be strongly pyroninophilic. The electron-microscopic study revealed big agglomerations of ribosomal RNA inside of pseudofibrillar structures of the cytoplasma. The possibility of a new nosological entity should be envisaged.

ISSN:0001-5792    

DOI:10.1159/000208155

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Haemoglobin Stanleyville II has been found several times in individuals from Central Africa.S This paper now reports its discovery in Alsace, in a family of long-standîng local ancestry

ISSN:0001-5792    

DOI:10.1159/000208156

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Homozygous haemoglobin LeporeBoston disease is described in an Iranian 16-year-old boy presenting the clinical manifestations of β-thalassaemia major. The parents were related (cousins), and both carriers of Leporetrait. It seems that the symptoms are milder in this casethan what reported before

ISSN:0001-5792    

DOI:10.1159/000208157

出版商:S. Karger AG    

年代:1975

数据来源: Karger