ISSN:0277-3740    

出版商:OVID    

年代:1987

数据来源: OVID

摘要:

Acanthamoebais a free-living ubiquitous ameba that is responsible for a small but increasing number of cases of keratitis. The infection is associated with minimal corneal trauma and soft contact lens wear. It typically presents as a unilateral central or paracentral corneal infiltrate, often with a ring-shaped peripheral infiltrate. The lesion is often confused with fungal, bacterial, or herpetic keratitis. Successful therapy hinges on early recognition and aggressive therapy with appropriate topical antiamebic medication, often in conjunction with penetrating keratoplasty. Thirty-five cases from the world literature are reviewed.

ISSN:0277-3740    

出版商:OVID    

年代:1987

数据来源: OVID

摘要:

Aniridia and the iridocorneal endothelial (ICE) syndromes both are conditions which include abnormalities of the cornea, iris, and progressive iridocorneal adhesions which may result in glaucoma. In order to investigate the similarities between aniridia and the ICE syndromes, we performed specular microscopy of the corneal endothelium in nine patients with aniridia. Morphology and density of the corneal endothelium appeared normal for age. We found no evidence of the beaten metal appearance classically seen on specular microscopy in patients with ICE symptoms. This study did not support either an anatomic or pathogenic relationship between aniridia and the ICE syndromes.

ISSN:0277-3740    

出版商:OVID    

年代:1987

数据来源: OVID

摘要:

The natural course of corneal epithelial erosions was studied retrospectively in patients who had undergone cataract extraction. Postsurgical epithelial defects occurred in 41 of 796 eyes (5.2%). No difference was noted in the incidence of corneal epithelial defects in eyes after intracapsular and extracapsular cataract extraction. Of the 41 eyes with postsurgical corneal erosion, 26 (63.4%) showed corneal epithelial defects by the fourth postoperative day. Two types of healing patterns were noticed: rapid healing, in which there was complete epithelial resurfacing within 4 days after the onset of corneal erosion, and prolonged healing, in which the period for complete epithelial resurfacing ranged from 6 days to 34 days. Since fibronectin has been reported to facilitate corneal epithelial migration and adhesion, we administered autologous fibronectin eyedrops in five cases in which corneal epithelial erosion developed after cataract surgery and epithelial defects persisted more than 7 days (except case 2). In all cases receiving fibronectin treatment, complete epithelial resurfacing occurred. In four of five eyes, fibronectin eye drops were effective in epithelial resurfacing within 3–9 days; in one eye, complete epithelial resurfacing took 23 days. The present results indicate that there are two types of epithelial erosion and that fibronectin eye drops might be one of the possible therapeutic approaches for the treatment of persistent epithelial defects. The weak adhesion of epithelial cells underlying basement membrane may be one of the causes of persistent epithelial defects after cataract surgery.

ISSN:0277-3740    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0277-3740    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0277-3740    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0277-3740    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0277-3740    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0277-3740    

出版商:OVID    

年代:1987

数据来源: OVID

ISSN:0277-3740    

出版商:OVID    

年代:1987

数据来源: OVID