摘要:

AbstractAn inhibition enzyme‐linked immunosorbent assay using monoclonal antibodies has been used to confirm the diagnosis of IgA type multiple myeloma in a small fragment (<10 g) of cranium from a medieval female. Further testing by sodium dodecyl sulphate‐polyacrylamide gel electrophoresis and immunoblotting showed that the IgA was mainly polymeric, suggesting that the individual would have suffered from a hyperviscosity syndrome. This is the first time that immunological assays have been used to diagnose multiple myeloma in ancient human tissue and have permitted speculation on associated clinical sympt

ISSN:1047-482X    

DOI:10.1002/oa.1390040102

出版商:John Wiley&Sons, Ltd.    

年代:1994

数据来源: WILEY

摘要:

AbstractRadiologic‐pathologic correlation is employed in pre‐Columbian tibia specimens as a means of understanding the characteristic alterations induced by untreated chronic osteomyeli

ISSN:1047-482X    

DOI:10.1002/oa.1390040103

出版商:John Wiley&Sons, Ltd.    

年代:1994

数据来源: WILEY

摘要:

AbstractMicroradiographs of early French medieval skeletal material diagnosed with leprosy show specific microscopic alterations, including isolated destruction, isolated bone formation and a combination of both processes, generally referred to as concentric remodelling. New bone deposition on the tibial diaphysis appears to follow the same processes. These observations parallel Coutelier's descriptions of bone remodelling observed in cases of amputated bones from leprous patients.

ISSN:1047-482X    

DOI:10.1002/oa.1390040104

出版商:John Wiley&Sons, Ltd.    

年代:1994

数据来源: WILEY

摘要:

AbstractInfective lesions of bone in leprosy are of two types. In the rhinomaxillary syndrome, superficial infective changes in the bones of the maxilla are due to the presence ofMycobacterium leprae.Lytic foci in the medulla or the outer cortical surface may be due toMycobacterium lepraeat the site as granulomatous lesions. The most frequent infective bone changes in leprosy are, however, sequelae of regional anaesthesia and soft tissue ulceration. The bone lesions are due to pyogenic bacteria and the nature of these infective lesions is similar to that in non‐leprous conditions. The pyogenic lesions in leprosy are restricted to the bones of the hands, feet and lower leg

ISSN:1047-482X    

DOI:10.1002/oa.1390040105

出版商:John Wiley&Sons, Ltd.    

年代:1994

数据来源: WILEY

摘要:

AbstractTorsion of the femur (ante‐ or retroversion) is a normal feature of the bone. It is related to the angular difference in orientation between the proximal and distal articulations. Torsion has been studied, bothin vivoand in dry bone, using a variety of techniques, from a traditional goniometer to radiographs and tomography. Problems with the accurate measurement of the angle of femoral torsion have been encountered by many workers, resulting in a wide range of reported values. A pilot study was undertaken to attempt to demonstrate the difficulties in measuring the angle in dry bone. It was demonstrated that, using standard equipment, measurement of this angle has very poor reproducibility. Is it possible, therefore, to measure the angle of femoral torsion accuratel

ISSN:1047-482X    

DOI:10.1002/oa.1390040106

出版商:John Wiley&Sons, Ltd.    

年代:1994

数据来源: WILEY

摘要:

AbstractThe accuracy of several methods of age estimation based on developing teeth was tested on 63 individuals of known age between 0 and 5.4 years from the Spitalfields Collection. The following methods of age estimation were tested: atlas method of Schour and Massler; diagram of Gustafson and Koch; mineralization age of some deciduous and permanent teeth, Moorrees, Fanning and Hunt, a modified method of Moorreeset al.by Smith, and quantitative methods using deciduous tooth length and weight regression equations, Deutsch, Tam and Stack. Accuracy was measured as the difference between dental age from the developing teeth and actual chronological age available from parish records.Results show that the atlas and diagram methods are considerably more accurate for this population and age group than methods based on mineralization stages of formation. Accuracy for the atlas method was 0.11 (± 0.30) year and diagram method 0.10 (± 0.37) year. The accuracy for methods based on mineralization stages of formation were considerably less accurate: 0.52 (± 0.62) year for deciduous teeth, 0.57 (± 0.42) year for permanent teeth and 0.29 (± 0.39) year for the same method but modified specifically for prediction. Significant differences (P<0.01) between dental and chronological age were apparent for methods based on mineralization stages.Accuracy of the quantitative methods during the first year of postnatal growth was high, the most accurate being deciduous molar length at 0.02 (± 0.15) year.Factors influencing accuracy and the problems encountered with the methods tested are discussed. The Schour and Massler atlas remains the recommended method of dental age estimation for this age group for reasons of accuracy and

ISSN:1047-482X    

DOI:10.1002/oa.1390040107

出版商:John Wiley&Sons, Ltd.    

年代:1994

数据来源: WILEY

ISSN:1047-482X    

DOI:10.1002/oa.1390040108

出版商:John Wiley&Sons, Ltd.    

年代:1994

数据来源: WILEY

摘要:

AbstractThe observed variation in the number of cross‐striations between Striae of Retzius in a sample of teeth from juveniles buried in the crypts of a London City church is presented. Estimates of intra‐and inter‐observer error in making such cross‐striation counts are discussed, together with implications for the estimation of age from perikymata counts on the tooth

ISSN:1047-482X    

DOI:10.1002/oa.1390040109

出版商:John Wiley&Sons, Ltd.    

年代:1994

数据来源: WILEY

ISSN:1047-482X    

DOI:10.1002/oa.1390040110

出版商:John Wiley&Sons, Ltd.    

年代:1994

数据来源: WILEY

ISSN:1047-482X    

DOI:10.1002/oa.1390040111

出版商:John Wiley&Sons, Ltd.    

年代:1994

数据来源: WILEY