ISSN:0425-1644    

DOI:10.1111/j.2042-3306.1987.tb02566.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:0425-1644    

DOI:10.1111/j.2042-3306.1987.tb02567.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:0425-1644    

DOI:10.1111/j.2042-3306.1987.tb02568.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

SummaryProteoglycan degradation is central to the development of degenerative joint disease. Proteoglycans may be degraded by lysosomal enzymes from chondrocytes, synoviocytes or leucocytes. Collagen and matrix degradation occurs either by direct damage or due to degrading enzymes released into synovial fluid. Once the pathological sequence has begun it continues in a cyclic manner unless arrested by the ability of chondrocytes to synthesise sufficient matrix components. Treatment should ideally be directed to this end.

ISSN:0425-1644    

DOI:10.1111/j.2042-3306.1987.tb02569.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

SummaryThis study describes the development of a radioaerosol technique for horses using99mtechnetium‐DTPA (diethylene‐triaminepentacetate). In 24 normal, adult horses, very satisfactory ventilation images were obtained with the technique. Four‐minute administrations of the aerosol resulted in a mean uptake of radioactivity in the lung fields of 3.02 mCi, with mean maximum counts (±sd) of 159,800± 75,000 per camera field. The mean clearance half‐time for the99mtechnetium‐DTPA from the lung fields was 55.6 ± 14.2 mins which is very similar to figures obtained for normal human and dog lungs. The results of this study suggest that ventilation imaging with99mtechnetium‐DTPA is a clinically practical method of obtaining regional information on ventilation functio

ISSN:0425-1644    

DOI:10.1111/j.2042-3306.1987.tb02570.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

SummaryThirteen (65 per cent) of 20 horses subjected to carbohydrate overload developed Obel Grade 3 lameness within 56 h. Increases in plasma endotoxin from control levels of less than 0.1 ng/litre to values ranging from 2.4 to 81.53 ng/litre were measured in 11 (85 per cent) of 13 horses during the onset of Obel Grade 3 lameness. Obel Grade 3 lameness was associated with rises in plasma Gram‐negative endotoxin levels in 11 (92 per cent) of 12 horses. Two peak increases separated by 16 h were verified in five (45 per cent) of 11 horses that exhibited both endotoxaemia and Obel Grade 3 lameness. The first peak occurred, on average, at 32 h and (he second peak at 48 h post overload when only one peak was measured, this occurred in four horses at the average time of 24 h whereas in another three horses only a 48 h or 56 h peak was detected after carbohydrate overloa

ISSN:0425-1644    

DOI:10.1111/j.2042-3306.1987.tb02571.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:0425-1644    

DOI:10.1111/j.2042-3306.1987.tb02572.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

SummaryBlood L lactate concentration and anion gap were measured in 32 horses suspected of having metabolic acidosis. There was good linear correlation between these variables (r = 0,90791, P<0.0001) and both were good prognostic indicators. Anion gap was a good indicator of the presence but not the severity of L lactic acidosis and was a slightly better prognostic indicator. The ability to predict survival was not improved by the measurement of L lactate in addition to anion gap.

ISSN:0425-1644    

DOI:10.1111/j.2042-3306.1987.tb02573.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

SummaryIntrauterine infusion of 1 per cent oyster glycogen solution was used to induce acute endometritis in four genitally normal mares. Numbers of viable neutrophils recovered in uterine washings had increased by 1 h after infusion and remained elevated for at least 72 h. There was a significant correlation between numbers of viable neutrophils and total protein concentrations and between prostaglandin (PG)F and PGE2concentrations in washings. There was also a significant relationship between concentrations of 15‐keto‐13, 14‐dihydro PGF2αin plasma and PGF in washings. Intrauterine concentrations of PGF were influenced by cycle stage and in turn the induced acute endometritis interfered with normal ovarian function. Mares with persistent endometritis had significantly higher concentrations of PGF and total protein and percentage of neutrophils and monuclear cells in washings than normal mares. White blood cells from mares were capable of producing PGF and PGE2in

ISSN:0425-1644    

DOI:10.1111/j.2042-3306.1987.tb02574.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:0425-1644    

DOI:10.1111/j.2042-3306.1987.tb02575.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY