ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1978.tb01041.x

年代:1978

数据来源: WILEY

摘要:

ABSTRACTThe following conclusions will be drawn from the data obtained in this study.1)Topical VA ointments which contain 5,000 IU and 10,000 IU VA respectively could not prevent n‐hexadecane‐induced epidermal proliferation and hyperkeratosis during the period studied.2)After the epidermal hypertrophy and hyperkeratosis were established, continuous application of VA ointments of 5,000 IU and 10,000 IU resulted in even greater activity of the enzymes than those observed with the control (hydrophilic ointment alone).3)Judging from the data obtained from the present study, VA ointment can be useful in the treatment of hyperkeratotic conditions characterized by the normal or decreased epidermal proliferation, because they promote the epidermal metabolic r

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1978.tb01042.x

年代:1978

数据来源: WILEY

摘要:

ABSTRACTThe killing action of near ultraviolet light emitted from a fluorescent black‐light lamp in the presence of 8‐methoxypsoralen was investigated using bacteriophage T4D and its mutants. It was found that a far ultraviolet‐sensitive mutant, T4v, was no more sensitive to the present photoreaction than the wild type. T4pxand T4ywere a little more sensitive than T4D. Contrary to the results of illumination with monochromatic light, exponential survival curves with pronounced shoulders were obtained. The reason for this finding is discussed on the basis of the mode of photorea

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1978.tb01043.x

年代:1978

数据来源: WILEY

摘要:

ABSTRACTIt was found that earthworms reacted sensitively and uniformly to ultraviolet (UV) irradiation in the levels of macroscopy, light microscopy and electron microscopy. In order to learn the probable role of superoxide radical and lipoperoxide on the mechanism of UV‐induced tissue damage, we studied the correlation of superoxide dismutase (SOD) and lipoperoxide, which was expressed as malondialdehyde content, in the UV‐irradiated earthworms.The SOD activity, which was assayed by the inhibitory effect of nitro blue tetrazolium reduction in the xanthine‐xanthine oxidase system, was initially elevated but later decreased gradually. Since this decrease preceded the UV‐induced pathological changes in the earthworm, it was hypothesized that the superoxide radical, the substrate of SOD, may be involved in this system. Lipoperoxide, however, did not increase in the same

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1978.tb01044.x

年代:1978

数据来源: WILEY

摘要:

ABSTRACTDuring an investigation of the mite fauna in Lagos, Nigeria, the following mites, namely,Dermatophagoides, Blomia, CheyletusandMesostigmataspecies were isolated.Blomiaspecies, a hitherto undocumented mite in Nigeria occurs to a marked extent in Nigerian houses. It was observed that location of houses seemed to affect the density and types of mites and that the majority of the houses were located in the damper suburbs of the city. It is suggested that in the prophylaxis of dust‐induced allergic diseases maintainance of adequate housing conditions would be of epidemiological importance. Furthermore, in the prevention of the occupational hazard of dust‐induced asthma, it is recommended that routine medical examination of prospective employees, particularly those in dust‐associated industries, should include pre‐employment allergic skin testing in order to ascertain sensitivity to industria

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1978.tb01045.x

年代:1978

数据来源: WILEY

摘要:

ABSTRACTA histochemical study of the presence of catecholamine‐containing cells (chromaffin cells) in human skin which had been treated by chromate‐bichromate solution according to Hillarp and Hökfelt then counter‐stained with various methods, was carried out.Small numbers of brown granules were disclosed in the upper part of the chromated normal dermis. They stained green with Giemsa or toluidine blue, showing similar staining properties to the adrenal medulla of rabbits treated in the same way. They were also found in large numbers in nevus pigmentosus and blue nevi, but were rarely seen in Recklinghausen's disease and atopic dermatitis.Although the above‐mentioned brown pigment is not likely to be catecholamine, other possibilities of the nature of the granules are discussed, with special reference to melanin and lipid

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1978.tb01046.x

年代:1978

数据来源: WILEY