ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1974.tb01825.x

年代:1974

数据来源: WILEY

摘要:

ABSTRACTSkin slices containing various types of hair follicles were obtained from both the bald and hairy regions of the scalp and from the chin and the back of adult stump‐tailed macaques and from the scalp of preadolescent and infant animals. These were incubated in TC 199 containing tritiated testosterone. Testosterone and its six metabolites were extracted and isolated by thin‐layer chromatography. The amounts extracted from anagen hair sheath, anagen hair bulb, and telogen hair sheath of both terminal and vellus hair were compared.No statistically significant differences were obtained from the comparison of the means of each sample group. But the amount of 5α‐dihydrotestosterone (5‐DHT) was comparatively higher than testosterone and androstenedione in the frontal area indifferent on age differences whereas the amount of 5‐DHT was lower in the occipital and back area.These data suggest the existence of regional differences in testosterone metabolism in the scalp skin. No clue was provided to make clear the genesis of male‐pattern baldness in the stump‐

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1974.tb01826.x

年代:1974

数据来源: WILEY

摘要:

ABSTRACTHuman and dog and rabbit skin blood vessel strips give contractile responses to catecholamines, serotonin, and angiotensin II. Alpha receptors for catecholamine can be demonstrated. Species and organ variations occur in the small vessel tissue response to bradykinin (dog), histamine (rabbit) and acetylcholine (lung). A prostaglandin‐contractile activity could be demonstrated on cutaneous vessels. This activity was most marked in dog paw vessels and rarely occurred in human skin. Potentiation of catecholamine by prostaglandin E‐, A‐ and F‐ contractions could be demonstrated. The prostaglandin receptor was not blocked by alpha or beta blocking agents. The prostaglandin response was related to calcium concentration and was unrelated to exogenous or endogenous cyc

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1974.tb01827.x

年代:1974

数据来源: WILEY

摘要:

ABSTRACTA case of tick bite in a 4‐year‐old Japanese boy is reported. The parasite was identified as an adult female tick,Ixodes persulcatusSchulze, which is one of the most common ticks in Ja

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1974.tb01828.x

年代:1974

数据来源: WILEY

摘要:

ABSTRACTTopical application under occlusion of 0.1% Vitamin A Acid (VAA) in polyethylene glycol to the non‐involved skin of psoriatics and to the skin of normal controls resulted in keratolysis, acanthosis, glycogen accumulation, and increased enzyme activity, though the changes are more marked in the former. Those changes occurred during the first week of application and did not progress further, in fact continued application resulted in a biochemical return toward normal.A Koebner phenomenon was not seen and the test is therefore not useful in bringing out latent psoriasi

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1974.tb01829.x

年代:1974

数据来源: WILEY

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1974.tb01824.x

年代:1974

数据来源: WILEY