ISSN:0192-0790    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

To evaluate the effect of anti-inflammatory drug therapy on ulcer healing, we studied retrospectively patient records listing the dual diagnoses of rheumatoid arthritis and peptic ulcer (1953–1975). Forty-three ulcers (23 gastric and 20 duodenal) occurred in 41 subjects. Evaluation of ulcer healing was possible in 35 patients, 27 of whom had continued on anti-inflammatory drug therapy while being treated for ulcer disease and eight who did not. In 21 of the 27 patients the ulcer healed; in six the ulcer failed to heal, including one who died from gastric carcinoma. Fourteen of the 21 patients whose ulcer healed were taking both aspirin and corticosteroids; in all eight patients who stopped taking anti-inflammatory drugs, the ulcers (eight gastric, one duodenal) healed. In six patients no evaluation was possible because the outcome of ulcer therapy was unknown. The numbers of patients not studied, unlisted or unretrieved are unknown, though probably small, and while no data are available on controls drawn from the same population or on the rates of spontaneous ulcer healing and recurrence in this population, our study nevertheless establishes that ulcer healing does occur in many patients with rheumatoid arthritis despite continued treatment with salicylate, corticosteroid, or other anti-inflammatory drugs.

ISSN:0192-0790    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

Previous reports of benign gastric ulcer with achlorhydria have recommended surgical removal of the ulcer, even though a malignant process had not been demonstrated. We report a patient with achlorhydria and a gastric ulcer who, at exploration 4 weeks after discovery, had only a healed ulcer. Its benign nature was demonstrated by endoscopic biopsies and cytology and confirmed at surgery. The patient has remained achlorhydric on follow-up and has not had further ulcers. We recommend that, after multiple endoscopic biopsies and cytology have adequately excluded a malignant process, a gastric ulcer be followed to complete healing, even in the presence of achlorhydria. If healing is incomplete by 6–12 weeks, surgical intervention should be contemplated, just as for more routine gastric ulcers.

ISSN:0192-0790    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

We approached the early diagnosis of gastric infiltrating carcinoma, scirrhous cancer, by a retrospective study of 19 patients, together with a prospective study of a single patient, by reexamination and follow-up of gastric roentgenographs and endoscopic films. This study suggests that an early feature of this type of gastric cancer might be IIc- or III+IIc-like depression in the body of the stomach, probably in the fundic region of the stomach. A shallow depression or a slight stiffness of the gastric wall may be one of the earliest roentgenographic or endoscopic findings helpful in early detection of this disease.

ISSN:0192-0790    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

We obtained cholangiographic demonstration of non-calculous acute biliary colic associated with common bile duct dilation in a 46-year-old woman with a 9-year history of postprandial right upper quadrant pain. Hepatic plexus vagectomy and cholecystectomy completely relieved her symptoms, now for a 10-year follow-up period.

ISSN:0192-0790    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

The right iliac fossasquelch sign, not previously associated with the irritable bowel syndrome, is found in over one-third of patients at diagnosis. It is found in one-quarter of patients who have not improved at follow-up, but is virtually absent in those who have improved. It is also found in patients with active regional enteritis. Fluid feces passing through bowel of decreased pliability may be the factor which allows elicitation of the sign.

ISSN:0192-0790    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

We made an observational study of traveler's diarrhea in all members of a 48-person medical seminar group during a trip to Egypt and the Nile in September 1979. In addition to comparing symptoms in those who took antibiotic prophylaxis with doxycycline and those who did not, we also took into account water and dietary restrictions. Although our study supports the use of prophylactic doxycycline, the response appears to be considerably influenced by dietary or water restrictions. This study emphasizes the need to assess diet and water intake of travelers when conducting trials of medication aimed at preventing traveler's diarrhea.

ISSN:0192-0790    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

We have seen three patients with acute ulcerative colitis after hydrogen peroxide enemas. The colitis is probably the result of the explosive entrance of gas into the loose connective tissues of the mucosa and submucosa of the rectum and sigmoid. Fortunately, it is transitory in nature, but it should be distinguished from ulcerative, ischemic, or pseudomembranous colitis.

ISSN:0192-0790    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

We describe a rare case of pancreatic pseudocyst developing in the spleen as a sequel to chronic pancreatitis in the absence of a recognizable pseudocyst in and around the pancreas. We assume that pancreatic secretions escaped through a tight adhesion between the tail of the pancreas and the splenic hilum.

ISSN:0192-0790    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

We studied a young man with persistent elevation of transaminases and indirect bilirubin following acute viral hepatitis. Liver biopsy showed chronic persistent hepatitis, and clinical evaluation was otherwise negative for significant liver disease. The indirect-reacting serum bilirubin rose after both caloric restriction and intravenous nicotinic acid, responses believed by some to be characteristic of Gilbert's syndrome. Fasting and postprandial serum bile acid conjugates were not elevated. These results suggest that “Gilbert's-like” aberrations in bilirubin metabolism may be part of the spectrum of chronic persistent hepatitis.

ISSN:0192-0790    

出版商:OVID    

年代:1981

数据来源: OVID