ISSN:0192-0790    

出版商:OVID    

年代:1988

数据来源: OVID

ISSN:0192-0790    

出版商:OVID    

年代:1988

数据来源: OVID

ISSN:0192-0790    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Campylobacter pylori clearly is a common inhabitant of the human stomach and is associated with nonautoimmune antral gastritis, chronic peptic ulceration, and non-ulcer dyspepsia. This editorial reviews whether therapy is now justified for patients with this infection. The criteria that must be fulfilled before an association can be considered to be of etiologic significance are discussed in relation toC. pyloriinfection and clinical disease. An overview of therapeutic approaches to eradicateC. pyloriis presented, emphasizing their limitations and hazards. It is concluded that prescribing treatment forC. pyloriinfection outside the setting of a controlled trial is currently not appropriate.

ISSN:0192-0790    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

The abnormalities of the esophagus and its motility in Chagas' disease are very similar to those in achalasia. But, gastrin levels in Chagas' disease are elevated, and generally the upper gastrointestinal tract, as well as the colon, are hyposensitive to this hormone. In this editorial, I discuss some of the differences in the physiology of the two disorders.

ISSN:0192-0790    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Dr. Ismar Boas (1858–1938) was the founder of the medical subspecialty of gastroenterology. In 1886, he opened in Berlin the first specialty clinic for the study of digestive diseases. In 1895, he founded the first journal devoted to gastroenterology. During his long and productive career, Boas was a pioneer in nearly all areas of his field. His most lasting scientific accomplishment is his work on occult bleeding, which first introduced the clinical importance of this abnormal finding for the early diagnosis of gastric carcinoma. Fifty years ago, in 1938, Ismar Boas killed himself as the Nazis occupied Vienna. In this article, we honor the memory of a great physician and retrace the circumstances of his death.

ISSN:0192-0790    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

We undertook a 12-year review of the elective and emergency surgery for duodenal ulcer in Queen Mary Hospital, Hong Kong, to ascertain whether the introduction of cimetidine as treatment for duodenal ulcer had led to a reduction in the number of elective and emergency operations being performed for duodenal ulcer. There was no decrease in the number of elective operations performed for duodenal ulcer. Indeed, in the same period, emergency operations for bleeding and perforated ulcers had increased.

ISSN:0192-0790    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Sixty-three consecutive reexcisions of bowel for recurrent Crohn's disease where the former excision had removed all apparent disease were studied. Nine pathologic parameters (small ulcers, granulomas, regeneration, metaplasia, sub-mucosal lymphoid follicles, transmural inflammation, large ulcers, sinuses, and strictures) were correlated to the interval of time since the former excision to document the disease progression. By regression analysis, only the presence of strictures of large ulcers correlated with time. First quartile times suggest that small ulcers and granulomas were the earliest lesions of those studied. Regeneration, metaplasia, sub-mucosal lymphoid follicles, and transmural inflammation appear to be sequelae of Ulceration. Sinuses and strictures are late complications of ulceration. The results confirm clinical, radiological, and subjective pathological impressions of the progress of the disease and suggest a central role for ulceration in this disease.

ISSN:0192-0790    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Resting energy expenditure and nitrogen balance were measured shortly after admission and shortly before discharge or colectomy in eight adult males hospitalized for active ulcerative colitis. The measured resting energy expenditure was 19% higher than that predicted by the Harris-Benedict formula (p > 0.01). Fecal and urinary nitrogen losses were 2.1 ±1.5 g/day and 13.6 ± 3.8 g/day, respectively. During the early hospitalization period, daily intakes of calories (1,826 ± 1,050 kcal) and protein (1.5 ± 0.4 g/kg) were not sufficient to maintain energy (—548 ± 964 kcal/day) and nitrogen (—1.5 ± 3.9 g/day) balances. Energy expenditure and nitrogen losses at the end of the study were similar to the values obtained on admission, but because of a voluntary increase in caloric (by 42%) and protein (by 37%) intake during the hospitalization both energy balance (+434 ± 409 kcal/day) and nitrogen balance (+4.6 ± 6.5 g/day) (p > 0.05) improved. These results suggest that, although the metabolic impact of active ulcerative colitis is mild, it does result in negative energy and nitrogen balances. Dietary intake can be voluntarily increased during hospitalization to improve energy and nitrogen equilibrium.

ISSN:0192-0790    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

We estimated the extent of the inflammatory mucosal lesion by colonoscopy and biopsy in 60 patients with their first attack of ulcerative colitis. Proctitis was found in 12, proctosig-moiditis in 19, left-sided colitis in 10, and extensive colitis in 19. Fourteen clinical variables and laboratory measurements (bowel frequency, stool consistency, rectal bleeding, fecal mucus/pus, temperature, pulse rate, white blood cell count, hematocrit, sedimentation rate, serum iron, serum albumin, serum α2-globulin, serum C-reactive protein, and seromucoids) were determined. All the variables except rectal bleeding and hematocrit were correlated (p > 0.001) with the extent of colitis. On stepwise discriminant analysis, only C-reactive protein distinguished proctosigmoiditis from more extensive disease at a level of p > 0.001; no other variables improved the discrimination. Cross-validation by the “jack-knife method” showed that 86.7% of patients were correctly classified, the errors consisting in underestimation of disease in 8/29 patients with extensive colitis.

ISSN:0192-0790    

出版商:OVID    

年代:1988

数据来源: OVID