ISSN:0009-7330    

出版商:OVID    

年代:1957

数据来源: OVID

摘要:

Multipolar recording apparatus has been used to study the pattern of ventricular excitation in experimental bundle-branch block. After block, the wave of activation spreads uniformly from the contralateral ventricle across the septum to the free wall of the homolateral ventricle. Septal activation consumes more time than in the normal. Changes occur in the site and extent of early endocardial activity in the blocked ventricle. Alterations in both septal and mural depolarization contribute to QRS changes. Endocardial depolarization is described during recovery from transient bundle-branch block.

ISSN:0009-7330    

出版商:OVID    

年代:1957

数据来源: OVID

摘要:

Localized acute cardiac lesions containing fibrinoid were produced in rabbits by carotid-jugular cross circulation or temporary arteriovenous shunts, using small amounts of heparin as anticoagulant. Excessive amounts of heparin markedly reduced the incidence of fibrinoid in the lesions, which suggests that the formation of fibrinoid was inhibited or its deposition in the heart prevented. The results of the experiments suggest that the shunting procedures not only produce mechanical damage to the heart, but also participate in the production of fibrinoid or its precursors, which is deposited in localized sites of cardiac damage.

ISSN:0009-7330    

出版商:OVID    

年代:1957

数据来源: OVID

摘要:

Serum of hypercholesterolemic rabbits, when pulsated for 72 hours at pressures of 300 mm. Hg/0 mm. Hg with a pulse rate of 80 produced a birefringent deposit in excised pieces of rabbit aortae. Serum from normal rabbits did not produce this deposit. The active component or components responsible for this deposit are in the β-lipoprotein fraction of serum. The birefringent material is detectable in serum by this method before lipoid degeneration of the arterial intima becomes apparent in the sacrificed animal.

ISSN:0009-7330    

出版商:OVID    

年代:1957

数据来源: OVID

摘要:

Hypothermic animals subjected to total venous inflow occlusion and open cardiotomy develop elevations in right atrial mean pressure and postmortem evidences of myocardial failure. Acetyl strophanthidin, given before inflow stasis, prevented myocardial failure and increased survival. Myocardial failure was attributed to anoxia resulting from decreased coronary blood flow and alterations in the oxygen content of the blood supplying the myocardium. Perfusion of the coronary system with small quantities of oxygenated blood obtained from donor animals permitted open cardiotomy with survival.

ISSN:0009-7330    

出版商:OVID    

年代:1957

数据来源: OVID

摘要:

In vivo cultivated connective tissue is rich in lipids. That obtained from man and chicken has larger concentrations of neutral fat and cholesterol than connective tissue of other species. Connective tissue synthesizes cholesterol and possesses a striking avidity for retention of either endogenous or exogenous cholesterol. The fibrous portion of sponge-connective tissue of the rabbit incorporates cholesterol at a characteristic rate, indicating some inherent inter-relationship between the lipid and the scleroprotein. Marked reduction of a previously elevated serum cholesterol in the rabbit does not lower connective tissue cholesterol concentration. Connective tissue of the rabbit intima requires prolonged exposure to an elevated serum cholesterol before increased cholesterol incorporation occurs.

ISSN:0009-7330    

出版商:OVID    

年代:1957

数据来源: OVID

摘要:

When signs of cerebral ischemia were induced by the administration of hexamethonium or head-up tilting, the cardiac output was reduced in all patients. Although the level of arterial pressure during cerebral ischemia varied between 34 and 100 mm. Hg, cerebral blood flow at this time was reduced to 30.8 ± 4.6 ml./100 Gm. brain/min. Despite a reduction in cardiac output averaging 47 per cent, approximately the same percentage was diverted to the brain during cerebral ischemia.

ISSN:0009-7330    

出版商:OVID    

年代:1957

数据来源: OVID

摘要:

An evaluation of the stability and accuracy of modern physiologic pressure measuring systems is reported with a brief review of some of the problems of catheter pressure recording. Evaluation of stability consisted of measuring the drift of the baseline and of the calibration factors of the gage and amplifier combination with time and temperature change. Evaluation of the accuracy of these pressure measuring systems consisted of determining their static accuracy, their dynamic accuracy, and the pressure errors introduced by catheter accelerations and bending.

ISSN:0009-7330    

出版商:OVID    

年代:1957

数据来源: OVID

摘要:

Epinephrine overdosage in intact rabbits caused significant modifications in plasma lipid distribution and transport, and phospholipid metabolism of plasma, liver and aorta. Aortic phospholipid synthesis was accelerated shortly after epinephrine injection and persisted for 24 hours, but plasma and liver turnover rates were maximally elevated after 48 hours. Changes in plasma neutral fat concentration were paralleled by alterations in the levels of Sf12–400 lipoproteins and a relationship between Sf0–12 and plasma cholesterol levels is suggested by the data.

ISSN:0009-7330    

出版商:OVID    

年代:1957

数据来源: OVID

摘要:

Continuous testosterone propionate administration, but not pretreatment, inhibited cholesterol-induced coronary atherogenesis in pullets. This inhibition was associated with depression of the plasma total cholesterol, phospholipids. c/p ratio and turbidity. Aortic atherogenesis was not affected.

ISSN:0009-7330    

出版商:OVID    

年代:1957

数据来源: OVID